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1.
National Journal of Andrology ; (12): 733-736, 2006.
Article in Chinese | WPRIM | ID: wpr-343531

ABSTRACT

The steroidogenic acute regulatory (StAR) protein is an essential component in the regulation of steroid biosynthesis in adrenal and gonadal cells. The StAR protein has a high tissue specificity, located on the mitochondrial membranes of some relative cells. It regulates the transfer of cholesterin from extracellular into intracellular and plays a dominant role in steroidogenic synthesis. Recent studies have also shown that the transcription and expression of StAR are modulated not only through the cAMP-PKA dependent pathway, but also by multiple hormones and cytokines, which contributes to the regulation of cholesterin synthesis.


Subject(s)
Animals , Humans , Mice , Rats , Cholesterol , Metabolism , Cholesterol Side-Chain Cleavage Enzyme , Metabolism , Ethisterone , Metabolism , Gene Expression Regulation , Mitochondria , Metabolism , Phosphoproteins , Genetics , Physiology
2.
Rev. argent. coloproctología ; 2(3): 144-50, sept. 1988.
Article in Spanish | LILACS | ID: lil-213981

ABSTRACT

Se hace una revisión bibliográfica de la patología en general para presentar un caso de endometrosis de ano en una paciente con antecedentes de una episiotomía lateral derecha, operada en dos oportunidades por presentar abcesos perianales; una tercera intervención por fístula perianal. El tratamiento fue quirúrgico y se realizó resección amplia del tumor localizado en ano con reparación esfintérica. Los resultados postoperatorios fueron satisfactorios. El informe histopatológico fue el de una endometrosis de ano.


Subject(s)
Humans , Female , Adult , Anus Neoplasms , Anus Neoplasms/classification , Anus Neoplasms/diagnosis , Anus Neoplasms/surgery , Anus Neoplasms/therapy , Endometrium/pathology , Rectal Fistula/surgery , Rectal Fistula/complications , Perineum/pathology , Androgens/therapeutic use , Ethisterone/therapeutic use , Infertility, Female/etiology
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