ABSTRACT
Trichophyton violaceum, a less common and geographically restricted infection is reported in a 18-day-old neonate. The diagnosis was made by potassium hydroxide of skin scraping examination and confirmed by culture. The patient was treated successfully with miconazole nitrate application. A large family with crowded living was considered the main predisposing factor.
Subject(s)
Antifungal Agents/administration & dosage , Extremities/microbiology , Face/microbiology , Female , Humans , India , Infant, Newborn , Miconazole/administration & dosage , Tinea/diagnosis , Tinea Capitis , Trichophyton/growth & developmentABSTRACT
The subcutaneous tissue of the hamster cheek pouch, a site of immunologic privilege, has been used to investigate the potential infectivity of different types of parasites. It has been demonstrated that the implantation of fragments of lesions induced by the fungus Lacazia loboi, the etiologic agent of Jorge Lobo's disease, into the subcutaneous tissue of the hamster cheek pouch resulted in parasite multiplication and dissemination to satellite lymph nodes16. Here we describe the evolution of lesions induced by the inoculation of the isolated fungus into this immunologically privileged site. The morphology of the inflammatory response and fungal viability and proliferation were evaluated. Inoculation of the fungus into the cheek pouch induced histiocytic granulomas with rare lymphocytes. Although fungal cells were detected for a period of up to 180 days in these lesions, the fungi lost viability after the first day of inoculation. In contrast, when the parasite was inoculated into the footpad, non-organized histiocytic lesions were observed. Langhan's giant cells, lymphocytes and fungal particles were observed in these lesions. Fungal viability was observed up to 60 days after inoculation and non-viable parasites were present in the persistent lesions up to 180 days post-inoculation. These data indicate that the subcutaneous tissue of the hamster cheek pouch is not a suitable site for the proliferation of Lacazia loboi when the fungus isolated from human tissues is tested.
Subject(s)
Animals , Male , Cricetinae , Blastomyces/immunology , Blastomycosis/immunology , Granuloma/pathology , Blastomyces/isolation & purification , Random Allocation , Cheek/microbiology , Cheek/pathology , Extremities/microbiology , Extremities/pathology , Granuloma/immunology , Granuloma/microbiologyABSTRACT
Se presenta un paciente de 69 años de edad con cuadro clínico e histopatológico compatible con piodermitis vegetante. Las lesiones de 2 años de evolución se localizan en extremidades superiores. En los exámenes bacterilógicos por puncón se aisló en dos oportunidades Stafilococus aureus. Se destaca la buena, pero lenta respuesta a la terapéutica antimicrobiana
Subject(s)
Humans , Male , Aged , Amoxicillin-Potassium Clavulanate Combination/therapeutic use , Extremities/microbiology , Skin Diseases/diagnosis , Skin Diseases/enzymology , Skin Diseases/therapy , Staphylococcus aureus/isolation & purification , Arm/pathologyABSTRACT
Neste trabalho, os autores estudam a localizaçäo de lesöes únicas de hanseníase, em 317 pacientes paucibacilares, registrados no ambulatório do CMS Jorge Saldanha e no Hospital Estadual de Curupaiti, ambos localizados em Jacarepaguá, Rio de Janeiro. A localizaçäo preferencial das lesöes, sua relaçäo com sexo e idade e os possíveis fatores de interferência nesta distribuiçäo na populaçäo estudada säo discutidos. Estes achados säo comparados com os resultados obtidos em pesquisas similares, realizadas por outros autores no contimente asiático e africano
Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Extremities/microbiology , Foot Dermatoses/microbiology , Hand Dermatoses/microbiology , Leprosy/transmission , Mycobacterium leprae/pathogenicity , Brazil , Leg Dermatoses/microbiologyABSTRACT
A case report is described here of an axillary pseudo-aneurysm associated with brachial plexus lesion, caused by a gun shot injury. Clinical Doppler, electrophysiological and neuro-vascular reconstruction in one stage with restoration of substantial functions in the upper limb