ABSTRACT
The Global Burden of Disease Study 2010 listed schistosomiasis among the leading 100 causes of death in Brazil, responsible for 3.6% of the estimated total of deaths globally. Eye and adnexa are very rarely affected by schistosomiasis mansoni, with limited documentation of ocular pathology in this setting. This short communication reports ocular histolopathological findings in a murine model of neuroschistosomiasis mansoni. Lesions were found in the bulbar conjunctiva, lacrimal gland, choroid and corneoscleral limbus.
Subject(s)
Animals , Male , Mice , Schistosomiasis mansoni/parasitology , Eye Infections, Parasitic/parasitology , Neuroschistosomiasis/parasitology , Schistosoma mansoni/isolation & purification , Schistosomiasis mansoni/physiopathology , Schistosomiasis mansoni/pathology , Brazil , Eye Infections, Parasitic/physiopathology , Eye Infections, Parasitic/pathology , Neuroschistosomiasis/physiopathology , Neuroschistosomiasis/pathology , Disease Models, AnimalABSTRACT
A neurorretinite subaguda difusa unilateral (DUSN) é uma forma de uveíte que pode potencialmente levar à cegueira. No Brasil e em outras partes da América do Sul, a neurorretinite subaguda difusa unilateral cada vez mais é considerada uma causa importante de uveíte posterior em crianças e em adultos jovens e saudáveis. Se diagnosticada e tratada ainda em fase inicial, permite uma resolução dos sintomas com melhora da acuidade visual. Caso progrida para a fase tardia, poderá acarretar uma perda visual significativa. Nesse estudo, por meio de uma revisão da literatura, descreve-se as principais características desta doença, incluindo os seguintes aspectos: histórico, etiologia, fisiopatologia, quadro clínico, diagnóstico, diagnóstico diferencial e tratamento.
Diffuse unilateral subacute neuroretinitis (DUSN) is a form of uveitis that can potentially lead to blindness. In Brazil and other parts of South America, diffuse unilateral subacute neuroretinitis is an important cause of posterior uveitis in children and healthy young adults. If diagnosed and treated in early stage, allows a resolution of symptoms with improvement of visual acuity. If the disease progresses to the late stage, can result in significant visual loss. In this study, through a literature review, we describe the main characteristics of this disease, including the following aspects: history, etiology, physiopathology, clinical features, diagnosis, differential diagnosis and treatment.
Subject(s)
Animals , Humans , Eye Infections, Parasitic , Retinitis , Diagnosis, Differential , Eye Infections, Parasitic/diagnosis , Eye Infections, Parasitic/physiopathology , Eye Infections, Parasitic/therapy , Larva , Retinitis/diagnosis , Retinitis/physiopathology , Retinitis/therapy , Uveitis/diagnosis , Visual AcuityABSTRACT
Os autores fazem uma revisäo da Síndrome da Imunodeficiência Adquirida em seus aspectos gerais. Focalizam as infecçöes oportunistas, relacionando-as com a contagem dos linfócitos T circulantes, e as afecçöes malignas associadas à doença. Chamam a atençäo para a evoluçäo e os aspectos clínicos para a menor incidência de manifestaçöes oculares
Subject(s)
Humans , Adolescent , Child , Adult , Eye Manifestations , Herpes Zoster Ophthalmicus/physiopathology , Eye Infections, Fungal/physiopathology , Eye Infections, Parasitic/physiopathology , AIDS-Related Opportunistic Infections/physiopathology , Lymphoma/physiopathology , Sarcoma, Kaposi/physiopathology , Acquired Immunodeficiency Syndrome/complicationsABSTRACT
To develop a method to analyse pupillary disturbances in patients with chronic Chagas disease in an endemic area, ten chagasic and ten normal subjects were matched according to sex, age and race. Pupillary diameter and area were determined using projection and topography techniques and compared between groups. Both pupils were visualised simultaneously. In each case three photographs were taken under standardised illumination. The first photo was obtained without medication, the second, 30 minutes after instillation of 0,1 per cent pilocarpine and the last 30 minutes after instillation of 3 per cent phenylephrine (60 minutes after pilocarpine). Pupils of chagasic patients had a statistically significant greater initial diameter and area, irregularity of the pupil border, greater percentual reduction in diameter and area after pilocarpine 0.1 per cent and greater percentual increase in diameter and area after 3 per cent phenylephrine eyedrops. The method developed for this study was considered satisfactory. The results suggest ocular autonomic nervous system disturbances in chagasic patients.
Subject(s)
Female , Humans , Male , Chagas Disease/complications , Eye Infections, Parasitic/physiopathology , Miotics/pharmacology , Phenylephrine/pharmacology , Pilocarpine/pharmacology , Pupil/drug effects , Chronic Disease , Chagas Disease/physiopathology , Pupil/physiologyABSTRACT
La toxocariasis es una parasitosis de distribución mundial que afecta principalmente a niños y adolecentes. El globo coular es afectado en su segmento posterior, existiendo varias presentaciones clínicas. Este trabajo describe retrospectivamente 4 pacientes con un diagnóstico clinico y serológico de toxocariasis ocular. Los pacientes fueron tratados médicamente con albendazol y prednisona. El tratamiento quirúrgico consistió en vitrectomía y membranectomía. Los resultados visuales dependieron del sitio y tipo de lesión encontrada en la retina que condicionó la posibilidad de tratamiento quirúrgico, y no del tipo de evolución de la enfermedad.
Subject(s)
Humans , Male , Female , Adult , Larva Migrans, Visceral/physiopathology , Larva Migrans, Visceral/therapy , Toxocariasis/physiopathology , Toxocariasis/parasitology , Eye Infections, Parasitic/physiopathology , Eye Infections, Parasitic/parasitology , Prednisone/administration & dosage , Prednisone/therapeutic use , Mebendazole/administration & dosage , Mebendazole/therapeutic useABSTRACT
Os autores apresentam um caso de infestaçäo presumida do globo ocular humano por larva de mosca. Foi caracterizado pela migraçäo da larva através do espaço sub-retiniano, produzindo alteraçöes oftalmoscópicas e angiofluoresceínicas que se acredita serem secundárias à oftalmoniíase intra-ocular sub-retiniana
Subject(s)
Humans , Male , Child , Eye Infections, Parasitic/physiopathology , Myiasis/pathology , Muscidae/parasitologyABSTRACT
We report three cases of spontaneous extrusion of cysticercosis. In two cases, it got extruded from the orbit and in one case from the subconjunctival space. Extrusion of cysticercosis was associated with improvement in clinical signs and symptoms.