ABSTRACT
Focal nodular hyperplasia (FNH) is a benign condition of the liver often discovered incidentally on radiological investigation. Although FNH is a well-described lesion in the literature considerable diagnostic problems regarding this entity still remains. We report a case of multiple FNH in a 23-year-old male patient detected as an incidental finding in autopsy. On gross examination FNH was not suspected because of the multiple lesions and the lack of central scar which is characteristically described in FNH. The diagnosis was established on histopathology after examination of multiple sections of the lesions.
Subject(s)
Autopsy , Focal Nodular Hyperplasia/diagnosis , Focal Nodular Hyperplasia/pathology , Histocytochemistry , Humans , Incidental Findings , Liver/pathology , Male , Microscopy , Reticulin/analysis , Silver Nitrate , Staining and Labeling/methods , Young AdultABSTRACT
Focal Nodular Hyperplasia is a benign lesion of the liver, which usually presents with one or two localizations. We report the uncommon case of a 51-year-old female who presents with right upper quadrant pain that worsened in the previous month, without association with feeding. Four hepatic lesions were evidenced at Computerized tomography, the largest being of 8 cm in diameter, of atypical behavior. She was submitted to hepatic segmentectomy of the segment III. The pathologic diagnosis returned focal nodular hyperplasia mixed hyperplastic and adenomatous sub-type. The patient had a good postoperative evolution and is in ambulatory follow-up.
Subject(s)
Female , Humans , Middle Aged , Focal Nodular Hyperplasia/pathology , Adenoma/pathology , Focal Nodular Hyperplasia/classificationABSTRACT
No abstract available.
Subject(s)
Adult , Humans , Male , Contrast Media , Focal Nodular Hyperplasia/pathology , Liver/pathology , Magnetic Resonance Imaging , Tomography, X-Ray ComputedABSTRACT
Fibrolamellar hepatocellular carcinoma (FLC) is a rare histologic variant of hepatocellular carcinoma that appears most commonly in teenagers and young adults. The diagnosis is often made incidentally and surgical resection is the only curative treatment. Here we report two cases of incidental FLC involving a 19 year-old male, initially diagnosed with screening abdominal ultrasound, and a 14 year-old female that presented with abdominal pain. Diagnostic workup consisted of abdominal PET/CT and MRI Imaging studies and tissue diagnosis was confirmed with percutaneous liver biopsy. Both patients were treated with radical liver resection/tumor excision. However, tumor recurrence was observed in both during short-term follow-up. The male patient was treated successfully with surgical treatment however the female patient succumbed top regression of disease.
Subject(s)
Adolescent , Female , Humans , Male , Young Adult , Carcinoma, Hepatocellular/surgery , Liver Neoplasms/surgery , Biopsy , Carcinoma, Hepatocellular/pathology , Fatal Outcome , Focal Nodular Hyperplasia/pathology , Focal Nodular Hyperplasia/surgery , Liver Neoplasms/pathology , Lymph Nodes/pathology , Neoplasm Recurrence, Local , Tomography, X-Ray Computed , Young AdultABSTRACT
An 8-year-old boy was admitted because of recurrent fever for 1 month with increased CRP and ESR. Ultrasound reviewed multiple, small, hypo-echoic, rounded and wedge-shaped nodules with diffuse blood flow in spleen and enlarged abdominal lymph nodes. The spleen was enlarged and no echoic space was found in the largest lesion on 5th day. After a positive mycoplasma pneumoniae (MP) IgM was reported on 6th day, azithromycin was used intravenously. The temperature returned to normal and CRP and ESR improved in a short period. The lesions and lymphadenopathy disappeared and MP IgM antibody became negative 6 months later.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Azithromycin/therapeutic use , Blood Sedimentation , C-Reactive Protein/analysis , Child , Focal Nodular Hyperplasia/pathology , Humans , Immunoglobulin M/analysis , Male , Pneumonia, Mycoplasma/blood , Spleen/pathology , Splenic Diseases/pathology , Tomography, X-Ray ComputedABSTRACT
Nodular regenerative hyperplasia of the liver [NRHL] is characterized by hepatocellular nodules without fibrous septa between the nodules, and has been described in association with certain diseases. The NHRL should be considered in a liver mass and coexisting portal hypertension. We described the case of a 33-year-old Iranian man with NRHL in association with essential thrombocythemia
Subject(s)
Humans , Male , Liver Diseases/pathology , Focal Nodular Hyperplasia/pathology , Hypertension, Portal/complications , Thrombocythemia, Essential/etiology , Focal Nodular Hyperplasia/etiology , Comorbidity , Collagen Diseases , Felty Syndrome , Heart Failure , Metabolic DiseasesABSTRACT
No abstract available.