ABSTRACT
AbstractBACKGROUND:Onychomycosis is a fungal infection of the nails caused in most cases by dermatophytes Trichophyton rubrum and Trichophyton mentagrophytes. Despite numerous available antifungal drugs for therapy of this infection, the cure rate is low, with high rates of relapse after treatment and side effects.OBJECTIVES:To present a new option for the treatment of onychomycosis, in search of a more effective and rapid method than conventional ones.METHODS:Patients underwent two sessions of CO2 fractional laser 10.600nm associated with photodynamic therapy. Mycological and digital photography were performed before and after the treatment.RESULTS:McNemar test with continuity correction and degrees of freedom = 1: for clinical cure rate, 13.06, with p=0.00005; for mycological cure, 17.05, with p=0.00005; 72% felt fully satisfied with the procedure.CONCLUSIONS:The use of fractional CO2 laser 10.600nm associated with photodynamic therapy can be effective in the treatment of onychomycosis, decreasing the risk of systemic lesions that may be triggered with prolonged use of oral antifungals.
Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Foot Dermatoses/therapy , Hand Dermatoses/therapy , Lasers, Gas/therapeutic use , Onychomycosis/therapy , Photochemotherapy/methods , Combined Modality Therapy/methods , Patient Satisfaction , Reproducibility of Results , Treatment OutcomeABSTRACT
Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Young Adult , Dermatology/statistics & numerical data , Foot Dermatoses/epidemiology , Hand Dermatoses/epidemiology , Onychomycosis/epidemiology , Onychomycosis/therapy , Brazil/epidemiology , Comorbidity , Exercise/physiology , Foot Dermatoses/diagnosis , Foot Dermatoses/microbiology , Foot Dermatoses/therapy , Hand Dermatoses/diagnosis , Hand Dermatoses/microbiology , Hand Dermatoses/therapy , Onychomycosis/diagnosis , Prevalence , Risk FactorsSubject(s)
Humans , Female , Middle Aged , Foot Dermatoses/therapy , Laser Therapy , Onychomycosis/therapy , TrichophytonABSTRACT
A tungíase é uma infestação zooantropofílica causada pela Tunga penetrans. É endêmica na América Latina e no Caribe. Ocorre, principalmente, em comunidades carentes e sem saneamento básico e em indivíduos que visitam áreas contaminadas. O local mais comum de penetração do ectoparasita é a região periungueal dos pés. Os autores mostram a ocorrência de uma forma disseminada num habitante da zona rural.
Tungiasis is a zoophilic and anthropophilic infestation caused by Tunga penetrans. It is endemic in Latin America and in the Caribbean. It occurs mainly in impoverished communities that have no access to basic sanitation and in individuals that visit contaminated areas. The most common penetration site of this ectoparasite is the periungueal region of the feet. The authors present its disseminated form occurring in a patient inhabiting a rural area.
Subject(s)
Adult , Humans , Male , Foot Dermatoses/diagnosis , Tungiasis/diagnosis , Foot Dermatoses/therapy , Tungiasis/therapyABSTRACT
A infecçäo dos pés é um dos principais e mais comuns problemas da diabetes mellitus. Cerca de 25 por cento dos pacientes sofrem deste mal durante a vida. Esta crônica e comprometedora complicaçäo da diabetes mellitus causa considerável sofrimento, mudanças no estilo e qualidade de vida do paciente, impedimento de suas funçöes normais, morbidade e, finalmente, em alguns casos, amputaçäo. Medidas terapêuticas correntes, juntamente com o manuseio adequado de todos os fatores de risco fisiopatológicos e complicaçöes, auxiliaräo a reduzir a taxa de incidência de infecçäo do pé diabético, assim como os custos de tratamento, hospitalizaçäo e amputaçäo, além de diminuir o sofrimento do paciente e produzir a melhoria de suas condiçöes gerais
Subject(s)
Humans , Diabetes Mellitus/complications , Diabetes Mellitus/physiopathology , Foot Dermatoses/etiology , Skin Ulcer/etiology , Amputation, Traumatic , Arthritis, Gouty/diagnosis , Diagnosis, Differential , Foot Dermatoses/microbiology , Foot Dermatoses/prevention & control , Foot Dermatoses/therapy , Joint Diseases/diagnosis , Risk Factors , Skin ManifestationsABSTRACT
A study to assess the effect of soap soaks and plain water soaks on the dry anaesthetic sole of 15 leprosy patients bearing multiple fissures and callouses is reported. A callous scraper devised by us was found effective. It is recommended that a hypotonic keratolytic solution such as toilet soap or plain water be used for soaking which has the effect of softening the keratin. It may be better to use soap solution for this purpose.