ABSTRACT
The visual results of laser photocoagulation for subfoveal choroidal neovascular membrane (CNVM) has not always been satisfactory. The surgical removal of the neovascular membrane may be another treatment option. To investigate the prognosis and risk factors of this surgery, we analyzed the results of surgical removal of subfoveal CNVM (23 eyes), subfoveal hemorrhage with CNVM (6 eyes), and subfoveal hemorrhage alone (6 eyes). The mean follow-up period was 17.7 months (range 2 to 47 months). The mean preoperative membrane size was 0.89 disc diameter and the mean postoperative retinal pigment epithelial (RPE) defect size was 1.33 disc diameter. Visual improvement was observed in 13 out of the 23 eyes (56.5%) with sufoveal CNVM, four out of the six eyes (66.6%) with subretinal hemorrhage and CNVM, and five out of the six eyes (83.3%) with subretinal hemorrhage only. The visual outcome of subfoveal CNVM surgery was related to the presence of a subfoveal RPE defect (p = 0.005) rather than to the size of the RPE defect. No recurrence of neovascular membrane was observed during the follow up period. In conclusion, surgical removal may be a good alternative treatment for subfoveal CNVM.
Subject(s)
Female , Humans , Male , Choroidal Neovascularization/surgery , Choroidal Neovascularization/diagnosis , Choroidal Neovascularization/complications , Comparative Study , Fluorescein Angiography , Fovea Centralis/surgery , Fovea Centralis/pathology , Fundus Oculi , Laser Coagulation , Middle Aged , Pigment Epithelium of Eye/pathology , Prognosis , Retinal Hemorrhage/surgery , Retinal Hemorrhage/diagnosis , Retinal Hemorrhage/complications , Retrospective Studies , Risk Factors , Visual AcuityABSTRACT
Apresentam uma revisäo atualizada de 5 dos principais temas em investigaçäo, em retina e vítreo. Eles säo: cirurgia subfoveal, transplante do epitélio pigmentar da retina, endofotocoagulaçäo sub-retiniana, fator de crescimento transformador ß2 e ativador do plasinogênio tissular