ABSTRACT
From January 2000 to May 2001 causes of infertility were studied for 250 couples, 193 [77.2%] of whom had primary infertility and 57 [22.8%] had secondary infertility. Male infertility was found in 36.8% of cases. The most common cause of female infertility was ovulation disorders [41%] while tubal obstruction contributed to only 5% of cases. Only 15% of the couples had unexplained infertility. Galactorrhoea and/or increased serum prolactin was seen in 60% of cases. Ultrasonographic detection of mature follicles was consistent with the results of cervical mucus study and endometrial biopsy in 90% of cases
Subject(s)
Adolescent , Adult , Female , Humans , Male , Middle Aged , Age Distribution , Anovulation/complications , Biopsy , Cohort Studies , Galactorrhea/complications , Hyperprolactinemia/complications , HysterosalpingographyABSTRACT
In this report we describe a 37 year old lady who was demonstrated to have hyperprolactinemia causing amenorrhea-galactorrhea syndrome. Computerized tomography scan done twice did not reveal any sellar or suprasellar abnormality and there was no clinical or biochemical evidence of primary hypothyroidism. She had regression of galactorrhea, resumed regular menstrual cycles, and conceived twice on bromocriptine therapy. Following her second delivery she noticed spontaneous remission of galactorrhea and, prolactin levels estimated multiple times were normal.
Subject(s)
Adult , Amenorrhea/complications , Female , Galactorrhea/complications , Humans , Hyperprolactinemia/complications , India , Remission, SpontaneousABSTRACT
Se estudia la historia clínica de 9 pacientas interesadas en la procreación. Todas ellas presentaban un nivel de prolactina elevada, infertilidad conyugal y alteración en los ciclos menstruales; casi todas (8/9), perturbación en la lactopoyesis. Se evalúan los resultados obtenidos con el uso oral de Parlodel, complementado con inductores de la ovulación; y se menciona la restricción que existe en nuestro medio para realizar los diferentes procedimientos diagnósticos orientados a definir la etiología del cuadro clínico antes indicado
Subject(s)
Humans , Female , Hyperprolactinemia/drug therapy , Bromocriptine/therapeutic use , Galactorrhea/complications , Infertility, Female/diagnosis , Menstruation Disturbances/complications , Hyperprolactinemia/complications , Lactation DisordersABSTRACT
A hiperprolactemia é um dos sinais mais associados aos problemas de esterilidade feminina e de disfunçäo ovarianas, acarretando quadros de amenorréia, de anovulaçäo, de opsomenorréia e de ciclo eumenorréico com alteraçäo na fase lútea. Säo analisados 48 casos selecionados nas clínicas particulares dos autores, distribuídos de acordo com as drogas de prolactina. Há 11 casos de hiperprolactinemia por iatrogenismo. O sintoma mais constatado na hiperprolactinemia foi a anovulaçäo. Este achado esteve presente em 48% de todas as pacientes. O motivo mais freqüente da consulta foi a esterilidade primária, que respondeu por mais de 50% do contingente total, englobando amenorréia, opsomenorréia e ciclo eumenorréico. Em mais de 50% das vezes, o resultado da dosagem da prolactina esteve compreendido entre 26 e 55ng.ml de plasma. Apenas 27% das pacientes conseguiram engravidar, provavelmente pela associaçäo de outros fatores. Nem todas as mulheres com hiperprolactinemia säo portadoras de galactorréia. Em nossos casos ela foi detectada em 77% das pacientes. Amenorréia secundária deve sempre servir de motivaçäo para diagnosticar hiperprolactinemia. Foram analisadas as condutas clínicas e qualificadas as formas de tratamento à base de brommocriptina