ABSTRACT
Se presentó un caso raro de ganglioneuroblastoma sacro en un paciente de 32 años de edad, con evolución tórpida. Se presentan datos clínicos, estudios imaginológicos e histológicos. Se realiza revisión del tema
This is a uncommon case of sacral ganglioneuroblastoma in a patient aged 32 with a torpid evolution. Clinical data, imaging and histological studies are showed. A review of this subject is carried out
Subject(s)
Humans , Ganglioneuroblastoma/pathology , Abdominal Neoplasms , Neuroblastoma/surgery , Sacrum/physiopathology , Tomography/methodsABSTRACT
Los tumores neuroblásticos son tumores del sistema nervioso periférico. Algunos inmaduros como el neuroblastoma tienen comportamiento muy agresivo, mientras otros como el ganglioneuroma son considerados benignos. Por su variada sintomatología, al neuroblastoma se le denomina "el gran simulador" y es caracterizado como enigmático. El dolor es la principal manifestación, así como también la distensión abdominal y la palpación de una masa abdominal.
Subject(s)
Humans , Female , Child , Ganglioneuroblastoma/surgery , Ganglioneuroblastoma/diagnosis , Ganglioneuroblastoma/pathology , Pancreatic Neoplasms/diagnosis , Abdominal Pain/etiology , Neoplasm Staging , Neuroblastoma/classification , Neuroblastoma/genetics , Neuroblastoma/pathologyABSTRACT
OBJECTIVE: To report a case of ganglioneuroblastoma of cerebellum, with emphasis to the neuroimaging and pathological findings. CASE REPORT: A one year and eight-month-old girl presented with a two-month history of hypoactivity and tremor in the legs. The MRI showed an enhancing cerebellar mass hypointense on T1 and hyperintense on T2-weighted images. The patient underwent a craniotomy with resection of the lesion. The histological and immunohistochemical studies defined the diagnosis of ganglioneuroblastoma. CONCLUSION: The MRI findings of our case showed no features which could help in the differentiation between ganglioneuroblastoma and the other common types of posterior fossa neoplasms in the pediatric population.
OBJETIVO: Relatar um caso de ganglioneuroblastoma no cerebelo, com ênfase aos achados de imagem e patologia. RELATO DO CASO: Paciente feminino de um ano e oito meses apresentou-se com hipoatividade e tremor nas pernas há dois meses. A RM demonstrou uma massa cerebelar hipercaptante, com hipossinal em T1 e hipersinal em T2. A paciente foi submetida a craniotomia com ressecção da lesão. Os exames histológicos e imuno-histoquímicos definiram o diagnóstico de ganglioneuroblastoma. CONCLUSÃO: Os achados de RM deste caso não demonstraram padrões que pudessem auxiliar na diferenciação entre ganglioneuroblastoma e os demais tumores que comumente acometem a fossa posterior de crianças.
Subject(s)
Female , Humans , Infant , Cerebellar Neoplasms/pathology , Cerebellum/pathology , Ganglioneuroblastoma/pathology , Craniotomy , Cerebellar Neoplasms/surgery , Diagnosis, Differential , Ganglioneuroblastoma/surgery , Infratentorial Neoplasms/pathology , Magnetic Resonance ImagingABSTRACT
Four cases of neuroblastomas, two cases of ganglioneuroblastomas and one case of ganglioneuroma diagnosed by fine needle aspiration cytology (FNAC) are presented. Five tumors were in the retroperitoneum and two tumors occurred in the posterior mediastinum. Complete clinical history, physical examination, radiological investigation, laboratory parameters, cytological study of multiple slides aided with special stains and cell block preparation of aspirated material helped in diagnosis of these tumours. Cytohistopathological correlation was carried out from surgically resected specimens and from autopsy studies.