Comparison of the efficacy of metronidazole and metronidazole plus probiotics capsule in the treatment of bacterial vaginosis among non-pregnant patients seen at the outpatient department of a tertiary hospital: A single blind randomized controlled trial / Philippine Journal of Obstetrics and Gynecology

BACKGROUND: Bacterial vaginosis (BV) is the most prevalent cause of symptomatic vaginitis. In the Philippines, prevalence of BV is at 28.16%. The mainstay for the treatment of BV is Metronidazole. Although antibiotic therapy has been shown to eliminate BV associated organisms, there is extremely high recurrence rate.OBJECTIVE: To compare the efficacy of metronidazole and metronidazole plus lactobacilli tablet in the treatment of bacterial vaginosis among non-pregnant patients seen at the outpatient department of a tertiary medical center.METHODOLOGY: The population included non-pregnant women ages 15 t0 44 years old, with bacterial vaginosis diagnosed by Amsel's criteria and Nugent's scoring. The participants were randomly assigned to their treatment group, one is Metronidazole only and other received Metronidazole plus Lactobacillus tablet. All participants followed up on day 8,15,22 and 56 from initiation of treatment resolution or persistence of symptoms and collection of vaginal specimen for gram stain and inquire on adverse effects.RESULTS: On day 8 treatment, there were significantly more participant in the metronidazole plus probiotic arm with an estimated lactobacilli count of more than 30/hpf as comapred to metronidazole alone. On day 15 post treatment, there was no statistically significant difference with the estimated Gardnerella vaginalis count, lactobacilli count, presence or absence of malodorous vaginal discharge between the metronidazole plus probiotic and the metronidazole alone arm. With metronidazole plus probiotic group, the proportion of women with less than 30 per hpf Gardnella vaginalis count and absent foul smelling vaginal discharge were accounted among 100% of the participants from day 8 to 56 post treatment. The early reduction in the causative agent and symptoms can be attributed to an increase in the estimated lactobacilli count sustained until 56 days post treatment metronidazole plus probiotic. However, from day 15 to 22 and 56 post- treatment, the proportion of participants who had a nugent's score of less than 4 were greater for both the metronidazole plus probiotic (100%) and metronidazole alone (95%) arm, when compared to day 8 post-treatment. This finding for the metronidazole plus probiotic group is due to sustained reduction in the Gardnella vaginalis count and increase in lactobacilli counts. Potentially , the metronidazole plus probiotic treatment was found to be more favorable in sustaining the normal flora and probiotic can be used as an adjunct may enhance the efficacy of metronidazole in the treatment of BV.CONCLUSION: Metronidazole plus probiotic and metronidazole only treatment are comparable in treating bacterial vaginosis. In terms of restoring and maintaining the normal flora, metronidazole plus probiotic appears to be more significantly efficacious. Probiotic in the form of lactobacilli is a promising adjunct to enhance the efficacy of metronidazole in the treatment of bacterial vaginosis.

Comparison of the efficacy of metronidazole and metronidazole plus probiotics capsule in the treatment of bacterial vaginosis among non-pregnant patients seen at the outpatient department of a tertiary hospital: A single blind randomized controlled trial / Philippine Journal of Obstetrics and Gynecology

BACKGROUND: Bacterial vaginosis (BV) is the most prevalent cause of symptomatic vaginitis. In the Philippines, prevalence of BV is at 28.16%. The mainstay for the treatment of BV is Metronidazole. Although antibiotic therapy has been shown to eliminate BV associated organisms, there is extremely high recurrence rate.OBJECTIVE: To compare the efficacy of metronidazole and metronidazole plus lactobacilli tablet in the treatment of bacterial vaginosis among non-pregnant patients seen at the outpatient department of a tertiary medical center.METHODOLOGY: The population included non-pregnant women ages 15 t0 44 years old, with bacterial vaginosis diagnosed by Amsel's criteria and Nugent's scoring. The participants were randomly assigned to their treatment group, one is Metronidazole only and other received Metronidazole plus Lactobacillus tablet. All participants followed up on day 8,15,22 and 56 from initiation of treatment resolution or persistence of symptoms and collection of vaginal specimen for gram stain and inquire on adverse effects.RESULTS: On day 8 treatment, there were significantly more participant in the metronidazole plus probiotic arm with an estimated lactobacilli count of more than 30/hpf as comapred to metronidazole alone. On day 15 post treatment, there was no statistically significant difference with the estimated Gardnerella vaginalis count, lactobacilli count, presence or absence of malodorous vaginal discharge between the metronidazole plus probiotic and the metronidazole alone arm. With metronidazole plus probiotic group, the proportion of women with less than 30 per hpf Gardnella vaginalis count and absent foul smelling vaginal discharge were accounted among 100% of the participants from day 8 to 56 post treatment. The early reduction in the causative agent and symptoms can be attributed to an increase in the estimated lactobacilli count sustained until 56 days post treatment metronidazole plus probiotic. However, from day 15 to 22 and 56 post- treatment, the proportion of participants who had a nugent's score of less than 4 were greater for both the metronidazole plus probiotic (100%) and metronidazole alone (95%) arm, when compared to day 8 post-treatment. This finding for the metronidazole plus probiotic group is due to sustained reduction in the Gardnella vaginalis count and increase in lactobacilli counts. Potentially , the metronidazole plus probiotic treatment was found to be more favorable in sustaining the normal flora and probiotic can be used as an adjunct may enhance the efficacy of metronidazole in the treatment of BV.CONCLUSION: Metronidazole plus probiotic and metronidazole only treatment are comparable in treating bacterial vaginosis. In terms of restoring and maintaining the normal flora, metronidazole plus probiotic appears to be more significantly efficacious. Probiotic in the form of lactobacilli is a promising adjunct to enhance the efficacy of metronidazole in the treatment of bacterial vaginosis.

Frecuencia de infecciones vaginales y lesiones intraepiteliales en las usuariasde los laboratorios clínicos de DinámicaIPS de la ciudad de Medellín (Colombia), 2005-2010: estudio descriptivo / Frequency of vaginal infections and intraepithelial lesions in a female population sample of Dinámica IPS, a clinical laboratory in Medellin, attended between 2005 and 2010

Determinar la frecuencia de infecciones vaginales y lesiones intraepiteliales en los resultados de laboratorio de las usuarias de los laboratorios clínicos de Dinámica IPS de la ciudad de Medellín, atendidas entre el 2005 y el 2010. Materiales y métodos:estudio descriptivo transversal con fuentes secundarias de los resultados de pruebas realizadas a usuarias de Dinámica IPS atendidas en el periodo de estudio, en el que se evaluaron variables como la edad y los resultados de citología vaginal (n= 261 789),Gram (n= 70 447) y directo de flujo vaginal (n= 89 527). Se excluyeron registros con información incompleta. Se realizó análisis estadístico con medianas y proporciones.Resultados: del total de muestras analizadas por citología vaginal (n=261 789), el 1,99% correspondían a lesiones escamosas, de éstas el 0,038% corresponde a muestras positivas de cáncer de cuello uterino confirmada por patólogo; el 8,01% corresponde a lesiones intraepiteliales de alto grado y el 36,13% a lesiones escamosas de bajo grado.En el examen de flujo vaginal por directo se encontraron 14 803 pruebas positivas(16,51%) para vaginitis por hongos, 19 079 (21,31%) para vaginosis bacteriana y 414(0,46%) para vaginitis por Trichomona; en el Gram se observó que el desequilibrio de la flora normal generado por Gardnerella ocupan la mayor frecuencia con 19 186 resultados positivos (27,23%). Conclusiones: los datos encontrados con relación a las frecuencias de lesiones escamosas intraepiteliales y de infecciones vaginales guardan relación con lo reportado en la literatura nacional; sin embargo, para los casos de atipia en células escamosas de significado no determinado se encuentra variación, probablemente por las características mismas de este tipo de atipias...

Characteristic of bacterial flora from the uterus in HanWoo cattle / 대한수의학회지

Uterine sterilization is important for improving fertility in cattle. This study compared bacterial flora in the uterus between healthy and repeat breeder cows (RBCs). The uterine flushing of six heifers, 13 healthy HanWoo cows and eight RBCs (HanWoo) were sampled, and 15 frozen semen samples were selected. Overall, 35 bacteria were identified from in HanWoo uterine flushing and semen. The bacterial genera identified from HanWoo uterine flushing were Alloiococcus, Bacillus, Enterobacter, Enterococcus, Erysipelothrix, Gardnerella, Granulicatella, Kocuria, Pantoea, Pasteurella, Rothia, Serratia, Sphingomonas, Staphylococcus, Stenotrophomonas and Streptococcus. The bacterial genera identified from HanWoo semen were Bacillus, Escherichia, Kocuria, Oligella, Pseudomonas, Serratia, Sphingomonas, Staphylococcus, Stenotrophomonas and Streptococcus. The prevalence and presence of the identified bacteria between healthy cows and RBCs differed significantly. Further studies are needed to determine the role of these bacteria in the uterus of HanWoo cattle with reproductive disorder.

Detection of Trichomonas vaginalis, Gardnerella vaginalis, and Candida Species in Affirm VPIII, Papanicolaou Smear Test and Gram Stain / 대한임상미생물학회지

BACKGROUND: Infectious vaginitis is caused primarily by three different groups of microbial pathogens (Trichomonas vaginalis, Candida spp., and Gardnerella vaginalis). The objective of this study was to compare the Affirm VPIII assay using a DNA hybridization technique with the Papanicolaou (Pap) smear test and the Gram stain in the detection and identification of these three organisms. METHODS: A total of 300 vaginal samples were collected from women that were either symptomatic for vaginitis or asymptomatic women that were being seen for routine obstetric or gynecological care. The presence of T. vaginalis, Candida spp., and G. vaginalis was evaluated by using the Affirm VIII assay (Becton Dickinson, USA), Pap smear test, and Gram stain method, respectively. RESULTS: With the Affirm VPIII assay, 1 (0.3%) patient tested positive for T. vaginalis, 99 (33.0%) patients were positive for G. vaginalis, and 18 (6.0%) were positive for Candida spp. The detection rates of Trichomonas infection, bacterial vaginosis and candidiasis by the Pap smear test and Gram stain method were 0.7% versus 0%, 16.3% versus 35.7%, and 1.7% versus 9.7%, respectively. The differences between the detection rates of the above three organisms between the Pap smear test and the Gram stain method were statistically significant (p<0.05). CONCLUSION: The Affirm VPIII assay was more sensitive than the Pap smear test and more specific than the Gram stain method for the detection and identification of these three organisms. In addition, the results of the Affirm VPIII assay are quick to obtain and are simple and easy to interpret.

Isolation and Antimicrobial Susceptibility of Microorganisms from Milk Samples of Jindo Dogs (Canis familiaris var. jindo) / 대한수의학회지

Lack of hygiene and puerperal mastitis are common causes of bacterial diseases in nursing neonates. The aim of this study was to isolate microorganisms from milk samples of healthy female Jindo dogs with suckling puppies and to investigate antimicrobial susceptibility against the isolated bacteria. Milk samples were collected from 120 udders of 12 lactating Jindo dogs that were 2~4 years old without any clinical diseases including mastitis. Bacteria were isolated from 64 milk samples (53.3%), either singly (76.6%) or in combination (23.4%). Staphylococcus (S.) spp. was the most common microorganisms (74.7%) isolated from canine milk, followed by Haemophillus spp. (10.9%), Streptococcus spp. (9.6%), Gardnerella spp. (2.4%) and Moraxella spp. (2.4%). The most frequently isolated organism was S. warneri (31.3%). Antimicrobial susceptibility of these bacteria was tested with 17 antimicrobial agents by Kirbyand Bauer standardized disc diffusion method. Results indicated that bacteria isolated from healthy canine milk were mostly susceptible to amoxicillin-clavulanic acid, cephalothin and ceftiofur, but were resistant to erythromycin, neomycin and tetracycline.

Prevalencia de microorganismos asociados a infecciones vaginales en 230 mujeres gestantes y no gestantes sintomáticas del Centro de Salud La Milagrosa en el municipio de Armenia (Colombia) / Prevalence of micro-organisms associated with vaginal infections in 230 symptomatic expectant and non-expectant women at La Milagrosa health center in Armenia, Colombia

Objetivos: determinar la prevalencia de los agentes etiológicos de las infecciones vaginales en mujeresembarazadas y no embarazadas sintomáticas del centro de salud “La Milagrosa”, de Armenia (Quindío,Colombia), en un periodo comprendido entre noviembre y diciembre de 2007 y enero de 2008.Materiales y métodos: estudio de prevalencia. Se tomaron muestras en 230 pacientes que consultaron por síntomas asociados a infección vaginal en el centro de salud “La Milagrosa”. A todas las pacientes se les tomó muestras de flujo vaginal parala medición del pH, test de amina, identificación microscópica de células clave (células epiteliales que contienen bacterias, indicando la presencia deGardnerella), Trichomonas vaginalis, levaduras e hifas. Se hicieron cultivos en agar sangre, Sabouraud y Mac Conckey y se realizó la técnica de tinción de Gram. Los datos fueron analizados en el programaEpi Info versión 6.Resultados: la principal causa de infección fue cocobacilos gram variable tipo Gardnerella (39 por ciento), seguida de Candida spp (6,5 por ciento y Trichomonas vaginalis (5,7 por ciento). Conclusiones: en pacientes sintomáticas de flujo vaginal se encontró mayor prevalencia de vaginosis bacteriana.

Objective: determining the prevalence of infectious agents responsible for vaginal infections in symptomaticwomen at La Milagrosa primary health center in Armenia (Quindío, Colombia), between November and December 2007 and January 2008.Materials and methods: a cross sectional study was carried out on 230 patients who consulted for vaginal discharge and symptoms. A sample of vaginal discharge was obtained from each patient. Each sample was analysed for pH, amines test, identification of clue cells containing bacteria as an indicator for Gardnerella infection, Trichomonasvaginalis and the presence of hifae or yeasts. All samples were also cultured on blood agar, Sabouraud and Mac Conckey media and Gram stained. Thedata was organised on an Excel spreadsheet and analysed using Epi Info software (version 6).Results: Gardnerella had the highest infectious agent prevalence (39 percent), followed by Candida spp (6.5 percent)and Trichomonas vaginalis (5.7 percent).

A Case of Neonatal Sepsis with Meningitis due to Gardnerella vaginalis / 대한주산의학회잡지

Gardnerella vaginalis is a normal component of the vaginal flora and is one of the organisms associated with bacterial vaginosis. It is rarely involved in neonatal infection. Although it is possible that G. vaginalis plays an etiologic role in bacteremia, facial cellulitis and abscess, conjunctivitis, infected cephalhematoma, scalp abscess, respiratory disease and meningitis in newborns, G. vaginalis is an uncommon pathogen of neonatal sepsis and meningitis. We report a 3,830 g term neonate with sepsis and meningitis due to G. vaginalis and review the characteristics of neonatal G. vaginalis infection reported in the literatures.

Drug-resistant Profiles of Clinical Isolates of Gardnerella vaginalis on Columbia Agar Base Supplemented with Human Erythrocyte Lysate and Horse Serum / 감염과화학요법

BACKGROUND: To the best of our knowledge, there has been no any report on the antibiotic susceptibility profile of Gardnerella vaginalis, determined in domestic area by the agar dilution method. Therefore, we studied on 49 strains of G. vaginalis by the agar dilution method. METHODS: One standard strain (ATCC 14018) and Forty-eight strains isolated from patients with increased vaginal discharge were included in this study. Columbia agar base containing 1% proteose peptone No. 3 was supplemented with horse serum (5%) and human erythrocyte lysate (5%) which was prepared by a new method, and this medium was used for the antibiotic susceptibility test. RESULTS: The MICs90 of clindamycin and ciprofloxacin were 0.3 g/mL and 0.6 g/mL, respectively. Amoxicillin, cefazolin, doxycycline, and erythromycin were hardly effective against most strains of G. vaginalis (NCCLS, U.S.A., 2001). Especially, MICs90 of both metronidazole and tinidazole were 80 g/ mL under micro-aerobic condition of 5% O2. CONCLUSION: For the treatment of Bacterial vaginosis, it is suggested that clindamycin or ciprofloxacin should be combined with vaginal tablet or gel of metronidazole rather than single administration of metrondazole or tinidazole.

Drug-resistant Profiles of Clinical Isolates of Gardnerella vaginalis on Columbia Agar Base Supplemented with Human Erythrocyte Lysate and Horse Serum / 감염과화학요법

BACKGROUND: To the best of our knowledge, there has been no any report on the antibiotic susceptibility profile of Gardnerella vaginalis, determined in domestic area by the agar dilution method. Therefore, we studied on 49 strains of G. vaginalis by the agar dilution method. METHODS: One standard strain (ATCC 14018) and Forty-eight strains isolated from patients with increased vaginal discharge were included in this study. Columbia agar base containing 1% proteose peptone No. 3 was supplemented with horse serum (5%) and human erythrocyte lysate (5%) which was prepared by a new method, and this medium was used for the antibiotic susceptibility test. RESULTS: The MICs90 of clindamycin and ciprofloxacin were 0.3 g/mL and 0.6 g/mL, respectively. Amoxicillin, cefazolin, doxycycline, and erythromycin were hardly effective against most strains of G. vaginalis (NCCLS, U.S.A., 2001). Especially, MICs90 of both metronidazole and tinidazole were 80 g/ mL under micro-aerobic condition of 5% O2. CONCLUSION: For the treatment of Bacterial vaginosis, it is suggested that clindamycin or ciprofloxacin should be combined with vaginal tablet or gel of metronidazole rather than single administration of metrondazole or tinidazole.

Diagnosis of Bacterial Vaginosis with Relation to Isolation of Gardnerella vaginalis

Among 104 patients who visited a local clinic with increased, bad-smelling vaginal discharge, twenty-nine women (27.9%) were found to have bacterial vaginosis (BV) according to the Amsel's composite clinical criteria (homogeneous thin gray discharge, positive amine test, vaginal pH over 4.5, positivity of clue cell by Gram stain). The specificity, sensitivity and positive and negative predictive values of the Amsel's composite clinical criteria were estimated in relation to the G. vaginalis isolation rate. Fifty-two strains of G. vaginalis (50%) were isolated from vaginal swabs taken from 104 patients. The sensitivities of clue cells and G. vaginalis isolation were both 96.6% (28) in the 29 BV patients. The specificities of clue cells and the presence of G. vaginalis were 85.3% and 68.0%, respectively. But the sensitivity, specificity, and positive and negative predictive values of the combination of clue cells and morphotype of G. vaginalis were 93.1%, 92.0%, 81.8% and 97.2%, respectively. The sensitivity, specificity and positive and negative predictive values of amine test were 89.7%, 98.7%, 96.2% and 94.9% in the 29 BV patients. Among 52 strains of G. vaginalis, 34 strains (87.2%) were isolated from the 39 clue cell positive samples and the remaining 18 (27.7%) from the 65 clue cell negative cases. Twenty-four strains (92.3%) were isolated from 26 amine test positive samples and the remaining 28 (35.9%) from 78 amine test negative cases. According to these results, it seems that the amine test is a useful test for the diagnosis of BV. However, we propose the combination criteria of clue cells and G. vaginalis morphotype in vaginal discharge should give more objective results than the amine test for the diagnosis of BV. The sensitivity and specificity of vaginal pH over 4.5 were 86.2% and 57.3%, and those of homogeneous discharge 93.1% and 65.3%, respectively. These two criteria were not as specific as clue cells and amine test for the diagnosis of BV. These results suggest that BV could be diagnosed more simply and precisely with the finding of clue cells spotted with Gram variable polymorphic bacteria by means of Gram stain of vaginal wall swabs.

Colpocitologia em ambulatório de ginecologia preventiva / Colpocytology in a preventive gynecological ambulatory

OBJETIVOS: Avaliar os resultados de colpocitologia oncótica de mulheres atendidas em ambulatório de ginecologia preventiva (Hospital das Clínicas da Faculdade de Medicina da Universidade de Säo Paulo). MÉTODOS: Foram estudadas 6821 mulheres submetidas a exame clínico e ginecológico com realizaçäo de colpocitologia oncótica pela técnica de Papanicolaou. Estas mulheres foram consideradas conforme a faixa etária em três grupos: abaixo de 40 anos, entre 41 e 60 anos e acima de 60 anos. RESULTADOS: Amaioria das mulheres reconhecem tanto a necessidade da colpocitologia como sua periodicidade, principalmente entre as mais jovens. As mulheres acima de 60 anos eram as que mais referiam (54,1 por cento) näo conhecer a necessidade da colpocitologia oncótica, nem sua periodicidade (58,8 por cento); o grupo que melhor referia conhecimento da necessidade e periodicidade da colpocitologia oncótica foi o de mulheres entre 40 e 60 anos. O material foi considerado insuficiente para análise em 15,1 por cento ou inadequado em 1,1 por cento, sendo os resultados: classe I (21,7 por cento), II (59,9 por cento), III (2,0 por cento), IV (0,1 por cento) e V (0,1 por cento). Näo houve diferença significativa em relaçäo à distribuiçäo dos casos de neoplasia intraepitelial (NIC) entre as faixas etárias. O achado microbiológico mais freqüente foi Gardnerella sp. (8,6 por cento). Presença de papilomavírus humano (HPV) foi significativamente menor nas mulheres acima de 60 anos. CONCLUSÖES: O diagnóstico de alteraçöes colpocitológicas relacionadas a neoplasias foi de 2,2 por cento com detecçäo de Gardnerella sp. como o agente microbiológico mais prevalente por este método. A distribuiçäo de infecçäo pelo HPV mostrou declínio com o aumento da faixa etária. As mulheres mais velhas foram as que menos apresentavam conhecimento sobre a realizaçäo de colpocitologia

Correlation of Diagnostic 4 Signs, Bacterial Vaginosis and Gardnerella vaginalis Isolation and Drug - resistant Profiles of Clinical Isolates

No Abstract Available.

Correlation of Diagnostic 4 Signs, Bacterial Vaginosis and Gardnerella vaginalis Isolation and Drug - resistant Profiles of Clinical Isolates

No Abstract Available.

Vaginosis bacteriana

Se denomina vaginosis bacteriana al flujo vaginal sin signos de inflamación clínica y ausencia notoria de leucocitos, hongos y parásitos como causantes de este síndrome, sin identificarse una bacteria específica. Se caracteriza por la disminución de lactobacilos aerobios, el aumento de los anaerobios (bacteroides, peptoestreptococos y mobiluncus) y anaerobios obligados como la Gardnerella y Mycoplasma; es decir es un trastorno polimicrobiano con disminución de la acidez vaginal. La mayor prevalencia y concentración de Garderella vaginalis encontrada en este síndrome, hace pensar en su posible participación pero no cómo único agente. Por otro lado, la vaginosis bacteriana afecta a mujeres en edad reproductiva...

Genital infections among women using various contraceptive methods in Basra, Iraq

A survey of women with abnormal vaginal discharge was conducted among patients attending an obstetrics and gynaecology clinic at Basra Hospital, Basra, Iraq, from September 1995 to June 1996. Out of 260 women examined, 250 [96.2%] were found to be infected with sexually transmitted and other genitourinary diseases, with a 16.2% incidence of multiple infections. This study compares the rate of infection by age group and contraception methods used. Significant findings include a 25.0% occurrence of Candida spp. among women using oral contraception and higher occurrence of Gardnerella sp. and Klebsiella spp. for women using an IUD as compared to nonusers

Detección oportuna de cáncer de cervix en mujeres indígenas, en el área rural de Guasuntos, Chimborazo 1997 / Opportune detection of the cancer of cervix in indigenous women, the rural area of Guasuntos, Chimborazo 1997

Se estudiaron 45 (12,5xcto) mujeres de la población rural de Guasuntos, al momento del estudio ninguna se encontraba embarazada ni tampoco había tomado ACO ni otro medicamento durante las últimas semanas, 51,2xcto no refirió sintomatología, 35(77,7xcto) fueron multíparas, 8(17,7xcto) menopáusicas, 4(9xcto) estaban en etapa de lactancia y 3 (6,6xcto) eran portadoras de T de Cu. La mayor parte de las pacientes presentó Clase II Inflamatoria, siendo mas frecuente el tipo moderado (75,7xcto) y en la edad de 20 a 29 años, de ellas 17 se encontraban asintomáticas y 25 fueron multíparas. El agente infeccioso más frecuente fue Cándida 20xcto, seguido de Gardnerella 17,7xcto y Tricomona 2,2xcto. La candidiasis fue más frecuente en el grupo de edad de 20 a 29 años y en las personas en etapa de lactancia. Apenas 2(4,4xcto) presentaron Clase III tipo Displasia leve, ellas se encontraban en el grupo de edad de 40 a 49 años, fueron multíparas, menopáusicas, infectadas por Gardnerella y asintomáticas. Se concluye que la sintomatología de estos procesos depende del grado de inflamación y que la multiparidad sumada a las normas de higiene inadecuadas, son el factor común que predispone a la Cervico-vaginitis y a la Displasia en las mujeres campesinas, de ahí que se requiere de ampliación de la cobertura del programa de DOC, pues consideramos que ellas tienen gran predisposición y que en algún momento de su vida presentarán alguna de estas anormalidades.

Incidencia de enfermedades infecciosas cervico-vaginales en el cantón Cevallos Tungurahua, mayo, 1996 septiembre, 1997

Estudio realizado en 140 mujeres del cantón Cevallos, parroquias y unidades que acudieron al Centro de Salud Area No. 9 a realizarse el examen de papanicolaou con el objetivo de prevenir el cánce cervico uterino, en el período de mayo 1996 a septiembre de 1997. Los resultados de citología son: inflamación en el 100 por ciento, con incremento de flora bacteriana, además se encuentra gérmenes específicos como: Gardnerella en un 25,7 pro ciento leptotrix en 17,8 por ciento, hongos en 14 por ciento, trichomonas en 5,7 por ciento candidiasis 3,5 por ciento metaplasia 1,4 por ciento, displasia 0.7 por ciento. Con el estudio realizado concluimos que la mayoría de las pacientes presentan una alta incidencia de flujo vaginal y prurito diagnóstico a través de la clínica y el papanicolaou y el citobactereológico debiéndose tomarse en cuenta para el tratamiento.

La gardnerellose bacterienne chez l'homme et chez la femme : traitement par l'association Amoxicilline-Metronidazole (Ospamox-Supplin) : etude preliminaire

20 Camerounais (10 femmes et 10 hommes; tous circoncis) en periode d'activite sexuelle presentant une vaginose bacterienne ont ete par l'association Amoxicilline-Metronidazole; pendant 10 jours. De bons resulats ont ete et ceci recurrences; 2 semaines apres la fin du traitement; ce resultat; malgre la taille de l'echantillon; suggerant la superiorite de ce schema therapeutique par rapport aux traitements actuels (Metronidazole seul ou Clindamycine). Enfin les troubles de l'erection semblent presque toujours associes a cette affection chez l'homme

Pesquisa de lesiones de cuello uterino por citología en población femenina del área rural de los Distritos Sanitarios Lagunillas y El Vigía del Estado Mérida / Cytological search for cervical uterine lesions in a female population from the rural area of the Sanitary Districts of Lagunillas and El Vigia, Merida, Venezuela

Con el propósito de determinar la incidencia de lesiones de cuello uterino en población femenina del área rural (Lagunillas y El Vigía, Estado Mérida, Venezuela), se realizó toma de muestra citológicas en 256 pacientes, con aplicación de una encuesta socio-sanitaria. El promedio de edad de las pacientes fue de 30 años, de las cuales 47.2 por ciento correspondió a casadas, 73 por ciento presentó grado de educación bajo; 77,6 por ciento ingreso mensual menor de cinco mil bolivares, predominando como ocupación oficios del hogar. La actividad sexual tiende a ser precoz, con promedio de 17.4 años; el 75.4 por ciento informó sobre un sólo compañero sexual, 74,8 por ciento de uso de algún método anticonceptivo y 45.3 por ciento de multiparidad. La actividad se realizó basicamente en consultas de planificación familiar en las que la sintomatología más frecuente fue el flujo vaginal. Los reportes citológicos revelaron diversa patología cérvico-uterina con predominio de los patógenos Candida, Gardnerella y Tricomona, además, cuatro de neoplasia intra-cervical, en edades comprendidas entre 23 y 53 años. Este hallazgo demuestra la necesidad de instituir la pesquisa como rutina dentro de las acciones preventivas que se cumplen en las instituciones de salud del área rural