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1.
RFO UPF ; 28(1)20230808. ilus, tab
Article in Portuguese | LILACS, BBO | ID: biblio-1523685

ABSTRACT

Angioleiomioma (AL) é um tumor benigno de origem perivascular que raramente é observado na cavidade oral, principalmente em localizações como a gengiva. Devido sua apresentação clínica inespecífica, os ALs podem mimetizar outras lesões orais, como tumores benignos de glândulas salivares e lesões reacionais, como o granuloma piogênico. O presente artigo objetiva relatar um caso raro de AL localizado em gengiva, em uma paciente de 19 anos. Clinicamente, a lesão apresentava-se como um tumor assintomático, oval, pedunculado, bem definido, com superfície lisa, consistência fibrosa e cor eritematosa, semelhante a um granuloma piogênico, Uma biópsia excisional foi realizada e o fragmento foi encaminhado para análise histopatológica, que revelou uma proliferação vascular de diversos calibres, contendo paredes musculares espessas e proliferação muscular adjacente, além de infiltrado inflamatório, predominantemente crônico, hemácias extravasadas e área de ulceração, consistente com o diagnóstico de AL inflamado. A histopatologia desempenha um papel importante no diagnóstico final de lesões raras e com características clínicas inespecíficas. A excisão cirúrgica da lesão é o tratamento de escolha mais eficaz para os ALs orais. (AU)


Angioleiomyoma (AL) is a benign tumor of smooth muscle of perivascular origin that is rarely seen in the oral cavity, mainly in locations like the gingiva. Due to their nonspecific clinical presentation, ALs can mimic other oral lesions, such as benign salivary gland tumors and reactional lesions, as a pyogenic granuloma. We reported a case of an AL located in the gingiva in a 19-year-old female patient. In clinical terms, the lesion was presented as an asymptomatic, oval, pedunculated, well-defined nodule with a smooth surface, fibrous consistency and erythematous color, similar to a pyogenic granuloma. An excisional biopsy was performed and the fragment was sent for histopathological analysis that revealed a vascular proliferation of different calibers, containing thick muscle walls and adjacent muscle proliferation, in addition to an inflammatory infiltrate, predominantly chronic, extravasated red blood cells and an area of ulceration, consistent with the diagnosis of inflamed AL. The histopathology plays an important role in the final diagnosis of rare lesions and with nonspecific clinical characteristics. The surgical excision of the lesion is the most effective treatment of choice for oral ALs. (AU)


Subject(s)
Humans , Female , Adult , Gingival Neoplasms/diagnosis , Gingival Neoplasms/pathology , Angiomyoma/diagnosis , Angiomyoma/pathology , Immunohistochemistry , Granuloma, Pyogenic/diagnosis , Granuloma, Pyogenic/pathology , Diagnosis, Differential
2.
Arch. pediatr. Urug ; 93(1): e305, jun. 2022. ilus
Article in Spanish | LILACS, UY-BNMED, BNUY | ID: biblio-1383646

ABSTRACT

El épulis congénito es una patología neonatal muy rara. Se trata de un tumor benigno pediculado de la mucosa de los maxilares, más frecuentemente localizado en maxilar superior en relación 2-3/1. Se describe el caso de un recién nacido de sexo femenino, de término, adecuado, vigoroso. Se constata al nacimiento la presencia de un épulis congénito que causa alteraciones de la succión. Se realiza intervención quirúrgica temprana, con resolución de la patología sin complicaciones.


Congenital epulis is a very rare neonatal pathology. It is a benign pedunculated tumor of the jaw mucosa, most frequently located in the upper jaw in a 2-3 / 1 ratio. The case of a newborn, female, term, adequate, vigorous is described. Noting at birth a congenital Epulis that causes suction alterations. Early surgical intervention is perfomed with resolution of the pathology without complications.


A epúlide congênita é uma patologia neonatal muito rara. É um tumor pedunculado benigno da mucosa dos maxilares, mais frequentemente localizado no maxilar superior na proporção de 2-3/1. Descreve-se o caso de um recém-nascido, do sexo feminino, a termo, adequado, vigoroso. Verificando ao nascimento uma Epúlide congênita que causa alterações na sucção. A intervenção cirúrgica precoce é realizada com resolução da patologia sem complicações.


Subject(s)
Humans , Male , Infant, Newborn , Gingival Neoplasms/surgery , Gingival Neoplasms/diagnosis , Gingival Neoplasms/pathology
3.
Chinese Journal of Stomatology ; (12): 410-414, 2022.
Article in Chinese | WPRIM | ID: wpr-935881

ABSTRACT

To provide references for the diagnosis and treatment of congenital granular cell tumor (CGCT), by comprehensive analysis of the clinical data, histopathological and immunohistochemical results. Patients with CGCT were involede, from March 2015 to November 2020, at the Department of Oral and Maxillofacial Surgery of the First Affiliated Hospital of Zhengzhou University. A total of 6 children, aged 3-16 days, 1 male and 5 female, 5 maxillary and 1 mandibular, with maximum tumor diameter of 6-70 mm, were included. The lesions of CGCT were single and connected to the alveolar ridge by a pedicle. The surface of the tumor was covered with a vascular network, and two cases had ulcers on the surface of the tumor. All 6 cases had the tumor removed surgically and there was no recurrence or metastasis in the follow-up visit. Although CGCT is rare, it is a benign tumor and generally does not recur or metastasize after surgery, and has a good prognosis. The prenatal imaging, clinical manifestations after delivery, pathological characteristics and immunohistochemical analyses may provide reference for early diagnosis and treatment of CGCT.


Subject(s)
Child , Female , Humans , Male , Pregnancy , Diagnosis, Differential , Gingival Neoplasms/surgery , Granular Cell Tumor/surgery
4.
Rev. ADM ; 78(5): 258-263, sept.-oct. 2021. ilus, tab
Article in Spanish | LILACS | ID: biblio-1344709

ABSTRACT

Introducción: La displasia epitelial oral (DEO) es la presencia de alteraciones celulares y tisulares, lo que puede significar una etapa anterior al desarrollo del cáncer. Múltiples marcadores han sido considerados para estimar su potencial neoplásico y evolución a carcinoma, incluyendo a la molécula p53, se considera como participe de diversos fenómenos de la homeostasis celular. Objetivo: Determinar la relación entre la inmunoexpresión de p53 DO-7 y PAb 240 con el grado de severidad de la displasia epitelial oral. Material y métodos: Se analizaron nueve muestras de DEO (tres para cada grado de severidad). La inmunoexpresión de p53 tipo silvestre (DO-7) y forma mutada (PAb 240), fue determinada a través de ensayo de inmunohistoquímica por peroxidasa. Se obtuvieron la media y desviación estándar y se realizó la prueba χ2 (p < 0.05). Resultados: La edad media fue de 65.7 ± 11.4 años, la zona anatómica con mayor presencia de DEO es el borde lateral de la lengua. Ocho de nueve muestras fueron positivas para DO-7 y solo dos para PAb 240. Conclusiones: Nuestros resultados indican que, aunque la expresión de p53 DO-7 podría estar relacionada parcialmente con la patogénesis de la displasia epitelial, no todas las displasias presentaron la forma mutada de p53 (PAb 240). Lo cual coincide con el comportamiento biológico incierto de las displasias al poder permanecer sin cambios, involucionar o transformarse


Introduction: Oral epithelial dysplasia (OED) is the presence of cellular and tissue alterations, which may mean a stage prior to the development of cancer. Multiple markers have been considered to estimate its pathogenic potential and evolution to neoplasms, including the p53 molecule, considered as participating in various phenomena of cellular homeostasis. Objective: To determine the relationship between the immunoexpression of p53 DO-7 and PAb 240 with the degree of severity of oral epithelial dysplasia. Material and methods: Nine OED samples were analyzed (three for each degree of severity). The immunoexpression of wild-type p53 (DO-7) and mutated form (PAb 240) was determined through a peroxidase immunohistochemical assay. The mean and standard deviation were obtained, and χ2 test (p < 0.05) were performed. Results: The mean age was 65.7 ± 11.4 years, with a greater presence of OED in the anatomical area of the lateral side of the tongue. Eight out of nine samples were positive for DO-7 and only two for PAb 240. Conclusions: Our results indicate that, although the expression of p53 DO-7 could be partially related to the pathogenesis of epithelial dysplasia, not all dysplasias presented the mutated form of p53 (PAb 240), which coincides that not all dysplasias have a potential for malignant transformation and that could be related to other oncogenic mechanisms (AU)


Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Aged , Precancerous Conditions , Immunohistochemistry , Genes, p53 , Gingival Neoplasms , Tongue Neoplasms , Pilot Projects , Carcinogenesis , Observational Study , Mexico
5.
West China Journal of Stomatology ; (6): 718-725, 2020.
Article in Chinese | WPRIM | ID: wpr-878401

ABSTRACT

Pregnancy epulis is a tumor-like lesion with high prevalence in China. The local lesion, the general condition of the pregnant patient, and the complications during treatment should be taken into consideration when making a treatment plan for pregnancy epulis. In this study, three representative pregnancy epulis cases were presented, and related studies at home and aboard were reviewed to summarize the etiology, differential diagnosis, treatment, and prevention of pregnancy epulis and share the clinical experience in the treatment of pregnancy epulis.


Subject(s)
Female , Humans , Pregnancy , China , Diagnosis, Differential , Gingival Diseases/diagnosis , Gingival Neoplasms , Prevalence
6.
Int. j. odontostomatol. (Print) ; 13(2): 230-234, jun. 2019. graf
Article in English | LILACS | ID: biblio-1002310

ABSTRACT

ABSTRACT: Oral melanoma (OM) is an extremely rare and aggressive malignancy. A 67-year-old patient presented with complains of a slightly symptomatic spot in the mouth since the past 2 years. Extraoral examination revealed left cervical lymphadenopathy, and intraoral examination a blue-black multinodular sessile mass, with irregular margins, involving the attached gingiva of teeth 27 and 28, extending to vestibular sulcus and hard palate, measuring approximately 3.5 cm. The lesion presented focal areas of ulceration. Panoramic radiograph did not show bone involvement. The main diagnostic hypothesis was oral melanoma. Microscopic findings of the incisional biopsy revealed a proliferation of densely pigmented pleomorphic cells, invading the subepithelial connective tissue in sheets or nests showing an organoid pattern. Immunopositivity for S-100, Melan-A and HMB-45 confirmed the diagnosis of melanoma. The patient was referred to an oncology hospital in which multiple metastases were detected, and the patient was subjected to palliative care. Herein we report an OM in advanced clinical stage, and discuss the clinical, morphological and immunohistochemical diagnostic criteria with emphasis on the importance of early diagnosis.


RESUMEN: El melanoma oral (MO) es una malignidad extremadamente rara y agresiva. Un paciente de 67 años acudió a consulta con la queja de una mancha intraoral ligeramente sintomática, presente desde hace dos años. Al examen clínico extraoral, se encontró adenopatía cervical del lado izquierdo, y al examen intraoral, se observó una masa sésil multinodular de color negro azulado, focalmente ulcerada, con bordes irregulares, afectando la encía de los dientes 27 y 28, extendiéndose hasta el surco vestibular y el paladar duro, midiendo aproximadamente 3,5 cm. La radiografía panorámica no mostró involucramiento óseo. La principal hipótesis diagnóstica fue MO. Los hallazgos microscópicos de la biopsia incisional revelaron una proliferación de células pleomórficas densamente pigmentadas, invadiendo difusamente el tejido conectivo en forma de sábanas o nidos con patrón organoide. La positividad inmunohistoquímica para S-100, Melan-A y HMB-45 confirmó el diagnóstico de melanoma. El paciente fue referido a un hospital oncológico, en el cual se le detectaron múltiples metástasis y fue sometido a cuidados paliativos. Este es el reporte de un caso de MO diagnosticado en estado avanzado, en el que se discuten los criterios clínicos, morfológicos e inmunohistoquímicos para su diagnóstico, haciendo énfasis en la importancia del diagnóstico temprano.


Subject(s)
Humans , Aged , Gingival Neoplasms/diagnosis , Melanoma/diagnosis , Prognosis , Gingival Neoplasms/etiology , Gingival Neoplasms/diagnostic imaging , Delayed Diagnosis , Melanoma/diagnostic imaging , Microscopy
7.
Rev. Fundac. Juan Jose Carraro ; 23(43): 14-18, 2019. ilus
Article in Spanish | LILACS | ID: biblio-1050064

ABSTRACT

El Cáncer Oral ocupa el sexto lugar entre los distintos tipos, y el 90% corresponde al Carcinoma de células escamosas de cavidad oral. Esta patología tiene una distribución mundial desigual. En Latinoamérica las incidencias más altas se reportan en Argentina, Sur de Brasil y Uruguay. La localización del tumor, el estadio clínico en que es diagnosticado, el tipo de tratamiento, entre otras variables, influyen en la supervivencia de los pacientes. Los distintos autores indican que en un alto porcentaje son diagnosticados en estadios avanzados lo que conlleva a una reducción evidente de la posibilidad de subsistir. Se presenta el caso clínico de un paciente sexo masculino de 75 años de edad que consulta por lesión tumoral en encía con 60 días de evolución. Se describen manifestaciones clínicas, radiológicas e histopatológicas. Se concluye en la necesidad de la detección y manejo oportuno por parte de odontólogos y médicos de ésta nosología (AU)


Subject(s)
Humans , Male , Aged , Gingival Neoplasms/radiotherapy , Carcinoma, Squamous Cell , Diagnosis, Differential , Argentina , Schools, Dental , Biopsy , Gingival Neoplasms/drug therapy , Diagnostic Imaging , Risk Factors , Combined Modality Therapy
8.
Int. j. odontostomatol. (Print) ; 12(2): 117-120, jun. 2018. graf
Article in English | LILACS | ID: biblio-954251

ABSTRACT

ABSTRACT: The appearance of mixed odontogenic tumors into the oral cavity is a rare event. It is considered that some mixed tumors are only a stage in the complete development of a hamartomatous formation such as ameloblastic fibroodontoma and odontoma. Both pathologies share in common cellular elements which at one point makes them indistinguishable from each other. We present the case of a 21 year old patient who showed a mandibular growth whose histological elements present characteristics of both pathologies. The treatment was surgical excision of the lesion. There were no complications or recurrences to periodic reevaluation.


RESUMEN: La aparición de tumores odontogénicos mixtos en la cavidad oral es un evento raro. Se considera que algunos tumores mixtos son solo una etapa en el desarrollo completo de una formación hamartomatosa como el fibro-odontoma ameloblástico y odontoma. Ambas patologías comparten elementos celulares comunes que en un punto los hacen indistinguibles entre sí. Presentamos el caso de un paciente de 21 años que mostró un crecimiento mandibular cuyos elementos histológicos presentan características de ambas patologías. El tratamiento fue la escisión quirúrgica de la lesión. No hubo complicaciones o recurrencias a la reevaluación periódica.


Subject(s)
Humans , Young Adult , Gingival Neoplasms/pathology , Odontoma/pathology , Odontogenic Cyst, Calcifying/pathology , Gingival Neoplasms/surgery , Radiography , Odontoma/surgery , Odontogenic Cyst, Calcifying/surgery , Fibroblasts
9.
Autops. Case Rep ; 8(1): e2018009, Jan.-Mar. 2018. ilus, tab
Article in English | LILACS | ID: biblio-905473

ABSTRACT

Odontomas are odontogenic tumors composed of a mixture of dental tissues. They are very common hamartomas of the jaws. However, their peripheral or gingival counterparts are extremely uncommon. The objective of this article is to report a rare case of gingival complex odontoma in an 11-year-old patient, and also to review all published cases of this type of lesion.


Subject(s)
Humans , Female , Child , Gingival Neoplasms/complications , Odontogenic Tumors/complications , Odontoma/complications
10.
Rev. Hosp. Ital. B. Aires (2004) ; 37(4): 146-148, dic. 2017. ilus
Article in Spanish | LILACS | ID: biblio-1095758

ABSTRACT

El linfoma difuso de células B grandes (LDCBG) es el linfoma más frecuente. La presentación clínica puede ser nodal o extranodal y sus síntomas dependen de la localización tumoral; en la mayoría de los casos están asociados a algún tipo de inmunodeficiencia. Referiremos un caso de LDCBG de presentación atípica en una localización muy infrecuente. Es importante tener en cuenta estas situaciones, ya que pueden simular otros procesos patológicos, retrasando así su correcto diagnóstico y por lo tanto un adecuado tratamiento. (AU)


Diffuse large cell lymphoma B (LDCBG) is the most common type of lymphoma. It´s clinical presentation can be nodal or extranodal and it's symptoms depend where the tumor is located and whether is associated or not with an immunodeficiency disease. We present an atypical presentation of a LDCBG in a very unusual location. It´s important to consider these kind of appearance, as they can mimic other oral pathological processes, delaying their correct diagnosis and therefore an appropriate treatment. (AU)


Subject(s)
Humans , Male , Aged , Lymphoma, Non-Hodgkin/diagnosis , Gingival Neoplasms/diagnostic imaging , Lymphoma, Large B-Cell, Diffuse/diagnosis , Lymphoma, Non-Hodgkin/classification , Lymphoma, Non-Hodgkin/etiology , Mouth Neoplasms/diagnosis , Lymphoma, Large B-Cell, Diffuse/therapy , Lymphoma, Large B-Cell, Diffuse/diagnostic imaging , HIV Seronegativity/immunology , Herpesvirus 4, Human/immunology , Oral Ulcer/pathology , Mouth Mucosa/pathology
11.
Int. j. odontostomatol. (Print) ; 11(2): 178-181, June 2017. ilus
Article in Spanish | LILACS | ID: biblio-893248

ABSTRACT

El Fibroma Odontogénico Periférico fue definido por la OMS en el año 2005 como una neoplasia benigna rara constituida por tejido fibroso maduro y una cantidad variable de epitelio odontogénico inactivo. Dada su presentación clínica, localización y baja prevalencia suele ser mal diagnosticado como una lesión reaccional. Se presenta un caso clínico de fibroma odontogénico periférico tratado mediante remoción quirúrgica y se realiza una revisión de la bibliografía respecto a la patología con el propósito de esclarecer algunos aspectos de esta lesión, además de incluirla dentro de los posibles diagnósticos diferenciales de lesiones reaccionales gingivales. El objetivo del siguiente artículo es presentar un caso clínico de FOP tratado mediante remoción quirúrgica y aportar en el diagnóstico diferencial de las lesiones reaccionales gingivales.


Peripheral odontogenic fibroma was described by the World Health Organization (WHO) in 2005, as a rare benign tumor containing mature fibrous connective tissue with a varying amount of inactive odontogenic epithelium. Though its clinical presentation, localization and low prevalence, it tends to be misdiagnosed as a reactive lesion. We present a case report of a Peripheral Odontogenic Fibroma treated by surgical resection and a narrative review of the literature with the purpose of clarifying different aspects of this lesion besides considering it as a possible differential diagnosis of reactive gingival lesions. The purpose of this article is to present a case report of peripheral odontogenic fibroma treated by surgical resection. Also to contribute to the differential diagnosis of gingival reactive lesions.


Subject(s)
Humans , Female , Middle Aged , Gingival Neoplasms/surgery , Gingival Neoplasms/diagnosis , Odontogenic Tumors/surgery , Odontogenic Tumors/diagnosis , Tooth Resorption/etiology , Gingival Neoplasms/pathology , Odontogenic Tumors/pathology , Diagnosis, Differential , Fibroma
12.
Rev. Nac. (Itauguá) ; 7(2): 37-39, dic 2015.
Article in Spanish | LILACS, BDNPAR | ID: biblio-884777

ABSTRACT

RESUMEN El épulis congénito del recién nacido es un tumor benigno, pediculado, de consistencia firme y tamaño variable, poco frecuente, de presentación bucal que tiene predilección por el sexo femenino. Se localiza habitualmente en la zona anterior y superior del maxilar superior. En caso de ser de gran tamaño puede interferir en la alimentación y dificultar la alimentación del neonato. La resección quirúrgica es el mejor tratamiento. El presente trabajo expone un caso y hace una revisión de la literatura.


ABSTRACT The congenital epulis of the newborn is a benign tumor, pedunculated, with a hard consistency and variable size rare, oral and of presentation that has a predilection for females. It is usually located in the anterior and superior maxilla. In case of big size it can interfere with feeding and can cause difficult neonatal feeding. Surgical resection is the best treatment. In this paper we presents a case and a review of the literature.


Subject(s)
Humans , Female , Infant, Newborn , Gingival Neoplasms/surgery , Gingival Neoplasms/congenital , Granuloma, Giant Cell/surgery , Granuloma, Giant Cell/congenital
13.
Archives of Orofacial Sciences ; : 34-40, 2015.
Article in English | WPRIM | ID: wpr-628605

ABSTRACT

Congenital epulis is a fairly rare soft tissue tumour occurring exclusively on the alveolar ridge of newborns. The exact origin of congenital epulis is still debatable. The objective of the study is to determine the clinicopathological features and immunohistochemical findings of congenital epulis. A retrospective study was carried out to determine the clinicopathological features of congenital epulis, diagnosed histologically in the main oral histopathology laboratory in Malaysia from 1967 to 2014. Immunostaining using vimentin, muscle specific actin, smooth muscle antigen, desmin, S100, CD34, CD68 and CD1a was carried out. Twelve cases of congenital epulis were reviewed. All of the patients were females and the presentation age ranged from 2 to 90 days. The patients comprised of 6 Malays, 3 Chinese, 2 Indians and 1 Orang Asli. Most of the cases (n=7) involved the maxillary ridge and presented as pedunculated well-defined lumps (n=8). Excisional biopsy was performed in all cases. Via immunohistochemistry, vimentin expression was observed in all cases; but negative for CD34, muscle specific actin, smooth muscle antigen, and desmin. CD1a and S100 positivity was seen in five cases. The interstitial cells were highlighted by CD68. Although congenital epulis has been first described 130 years ago, the exact nature of its histogenesis remains a mystery.


Subject(s)
Gingival Neoplasms
14.
West China Journal of Stomatology ; (6): 107-108, 2015.
Article in Chinese | WPRIM | ID: wpr-261127

ABSTRACT

Myeloid sarcoma (MS) is a localized extramedullary mass of immature granulocytic cells. MS may be found in any location, but intraoral occurrence is rare. This report presents a case of MS in the gingiva.


Subject(s)
Humans , Gingiva , Gingival Neoplasms , Sarcoma, Myeloid
15.
Article in English | IMSEAR | ID: sea-156561

ABSTRACT

Congenital epulis (CE) or “Granular cell epulis” also previously termed as “Neumann’s tumor” is a benign growth arising from the mucosa of the gingiva, typically seen as a mass protruding from the infant’s mouth, often interfering with respiration and feeding. These tumors generally present as a single mass arising from the upper alveolus. We report a rare case of two congenital epulides arising from the maxillary and mandibular alveolus in a day old female infant, which was surgically excised, allowing for early initiation of breast feeding. The tumor cells stained negative for S100 protein hence differentiating from other granular cell tumors. The clinical presentation, differential diagnosis in regard to the various neonatal oral swellings and the management of CE has been discussed.


Subject(s)
Gingival Neoplasms/congenital , Gingival Neoplasms/diagnosis , Gingival Neoplasms/therapy , Granuloma, Giant Cell/congenital , Granuloma, Giant Cell/diagnosis , Granuloma, Giant Cell/therapy , Humans , Infant
16.
Int. j. odontostomatol. (Print) ; 8(1): 147-151, Apr. 2014. ilus
Article in English | LILACS | ID: lil-711560

ABSTRACT

Peripheral ossifying fibroma (POF) is a relatively uncommon gingival growth that is considered to be reactive in nature and appear secondary to irritation or trauma. It presents as an exophytic growth with smooth surface. POF in older age group, observance of calcification in radiograph of excised specimen, pathologic migration, mobility and size greater than 2 cm is an occasional entity. The article presents such a rare case of POF in a 60-year-old female patient which was treated by surgical excision. This case contradicts the logic that this lesion occurs in teenagers and in second and third decades of life


El fibroma osificante periférico (FOP) es un crecimiento gingival poco común, considerado reactivo por su naturaleza y en general se manifiesta secundario a una irritación o trauma y se presenta como un crecimiento exofítico de superficie lisa. En grupos de mayor edad, el FOP muestra calcificación radiográfica, migración patológica, movilidad y un tamaño mayor de 2 cm, es de carácter ocasional. Se presenta un caso raro de FOP en una paciente de 60 años que fue tratado mediante excisión quirúrgica. Este caso, contradice su lógica de aparición en adolescentes o adultos entre la segunda y tercera década de la vida


Subject(s)
Humans , Female , Middle Aged , Bone Neoplasms/surgery , Bone Neoplasms/diagnosis , Gingival Neoplasms/surgery , Gingival Neoplasms/diagnosis , Fibroma, Ossifying/surgery , Fibroma, Ossifying/diagnosis , Calcinosis
17.
International Journal of Oral Science ; (4): 185-187, 2014.
Article in English | WPRIM | ID: wpr-358148

ABSTRACT

Spindle cell lipoma (SCL) is a benign lipomatous neoplasm typically located in the posterior neck and back of older males. It presents as a well-circumscribed mass in the buccal mucosa, tongue, floor of the mouth or hard palate. There are only two case reports of SCL in the gingiva and alveolar ridge. Here, we report a case of SCL in the mandibular mucogingival junction of a 68-year-old male. Clinical, histopathological and immunohistochemical findings are presented. Although oral SCL is rare, it should be considered in the differential diagnosis of spindle cell neoplasms occurring in the oral cavity.


Subject(s)
Aged , Humans , Male , Adipocytes , Pathology , Antigens, CD34 , Diagnosis, Differential , Follow-Up Studies , Gingival Neoplasms , Pathology , Lipoma , Pathology , Mandible , Proto-Oncogene Proteins c-bcl-2 , S100 Proteins
18.
Singapore medical journal ; : e152-5, 2014.
Article in English | WPRIM | ID: wpr-244789

ABSTRACT

Sarcomatoid carcinoma is a rare, malignant biphasic neoplasm with an epithelial and a spindle cell component. Primary sarcomatoid carcinomas arising from mandibular gingiva are known to be extremely rare, with only one case reported to date. Herein, we discuss the radiographic and computed tomographic appearances and pathological features of primary mandibular sarcomatoid carcinoma, which was confirmed by clinicopathology, in a 72-year-old man. In addition, we present a brief review of the relevant literature.


Subject(s)
Aged , Humans , Male , Bone and Bones , Diagnostic Imaging , Carcinoma , Pathology , Carcinoma, Small Cell , Pathology , Carcinosarcoma , Pathology , Gingiva , Pathology , Gingival Neoplasms , Pathology , Mandibular Neoplasms , Pathology , Sarcoma , Pathology , Tomography, X-Ray Computed
19.
Chinese Journal of Stomatology ; (12): 652-656, 2014.
Article in Chinese | WPRIM | ID: wpr-360477

ABSTRACT

<p><b>OBJECTIVE</b>To examine the cytokeratin expression in cervical lymph nodes of patients with mandibular gingival squamous cell carcinoma and its clinical significance.</p><p><b>METHODS</b>The data of 42 cases with mandibular gingival squamous cell carcinoma after operation from July 2009 to December 2012 were included. Forty-two patients (male = 27, formale = 15) were included, with a mean age of 54.1 years (range 27-77). The lesions were staged (stage I:9, stage II:16, stage III:6, stage IV:11). The cervical lymph nodes were examined by immunohistochemistry and HE. The cytokeratin expression in the lymph nodes was analyzed.</p><p><b>RESULTS</b>The rates of lymph nodes metastasis detected by routine HE staining, serial sections HE staining and IHC were 8.0% (47/585), 9.6% (56/585) and 12.8% (75/585), respectively. There was significant difference (χ(2) = 7.17, P < 0.01) in the diagnosis of lymph nodes metastasis between IHC and routine HE staining, There was no significant difference between IHC and serial HE staining (χ(2) = 3.10, P > 0.05). Metastasis occurred mainly in the Level I, II and III. Nineteen lymph nodes in 12 patients were found micrometastasis with IHC. Serial sections and routine HE staining did not find micrometastasis.</p><p><b>CONCLUSIONS</b>CK markers is sensitive in detecting lymph node metastasis of mandibular gingival squamous cell carcinoma.</p>


Subject(s)
Adult , Aged , Humans , Male , Middle Aged , Carcinoma, Squamous Cell , Metabolism , Gingiva , Gingival Neoplasms , Metabolism , Immunohistochemistry , Keratins , Metabolism , Lymph Nodes , Lymphatic Metastasis , Mandible , Neck , Neoplasm Staging , Staining and Labeling
20.
Braz. dent. j ; 24(4): 420-427, July-Aug/2013. tab, graf
Article in English | LILACS | ID: lil-689823

ABSTRACT

Central giant cell granuloma (CGCG) is a benign jaw lesion predominantly found in the mandible of young female patients with a variable clinical behavior. Although surgical management is regarded as the main treatment modality for this lesion, the use of intralesional injections of steroids has been recently advocated for its treatment. In addition to this conservative management, the use of fine needle aspiration cytology (FNAC) for diagnosing CGCGs has been proven a safe and efficient approach, especially useful in cases with lesions located in esthetic regions. Herein, it is described a case of CGCG extending to the overlying gingiva of a 15-year-old male patient diagnosed by FNAC and subsequently treated with intralesional injections of a solution of triamcinolone acetonide and ethanolamine oleate that led to an important clinical remission, allowing a more conservative surgical procedure for preservation of gingival esthetics. Therefore, both procedures can be considered as management options for CGCG of the jaws.


O granuloma central de células gigantes (GCCG) é uma lesão benigna dos maxilares predominantemente encontrada na mandíbula de pacientes jovens do sexo feminino com um variado comportamento clínico. Apesar de o manejo cirúrgico representar a principal modalidade terapêutica para esta lesão, o uso de injeções intralesionais de esteróides tem sido recentemente proposto para seu tratamento. Além do manejo conservador, o uso da punção aspirativa por agulha fina (PAAF) para o diagnóstico do GCCG tem sido comprovado ser uma abordagem segura e eficiente, especialmente útil em casos de lesões localizadas em regiões estéticas. Descrevemos aqui um caso de GCCG estendendo-se para a gengiva adjacente em um paciente do sexo masculino, 15 anos de idade, diagnosticado por meio da PAAF e subsequentemente tratado com injeções intralesionais de uma solução de acetato de triancinolona e oleato de etanolamina que levou a uma importante remissão clínica, permitindo a realização de uma abordagem cirúrgica conservadora preservando a estética periodontal. Por este motivo, ambos os procedimentos podem ser considerados opções de manejo para o GCCG dos maxilares.


Subject(s)
Adolescent , Humans , Male , Biopsy, Fine-Needle , Gingival Neoplasms/drug therapy , Gingival Neoplasms/pathology , Granuloma, Giant Cell/drug therapy , Granuloma, Giant Cell/pathology , Oleic Acids/administration & dosage , Triamcinolone Acetonide/administration & dosage , Injections, Intralesional
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