frequency of malignancy in nodular goiter - a single center study

To find out the frequency of malignancy in nodular goiters. A total of 204 cases were studied in the department of ENT and Head and Neck surgery, Hayatabad Medical Complex, Peshawar. The duration of this descriptive study was from June 1, 2008 to May 31, 2010. After taking informed consent, a detailed history was obtained. Clinical and laboratory investigations were carried out as an aid to diagnosis and determine the patients' fitness for surgery. Patients with nodular goiters were categorized into two categories i.e., Solitary thyroid nodule and multinodular goiter. Surgically resected thyroid specimens were examined histopathologically. The data was analyzed using SPSS 16.0 for windows to determine the frequency of malignancy in nodular goiter. Ages of the patients ranged from 17 to 84 years with a mean age of 37 +/- 12.48 years. The male to female ratio was 1:3:5. 18.14% cases presented as solitary thyroid nodules [STN] and 81.86% as multinodular goiters [MNG]. Out of the total 83.82% cases were benign and 16.18% cases were malignant. The prevalence of malignancy in multinodular goiter was 14.37% and in the solitary thyroid nodules as 24.32%. Papillary carcinoma was the commonest malignancy followed by follicular carcinoma. The prevalence of cancer is significant in nodular goiters and these malignant tumours are usually of the papillary type. Solitary thyroid nodules have more chances of being malignant than multinodular goiter

Recurrent laryngeal nerve injury; a risk in thyroid surgery

Aim of this study was to find out the frequency of recurrent laryngeal nerve injury in different types of thyroid surgery. An experimental study. The study was carried out at Combined Military Hospital, Rawalpindi from January 2001 to July 2002. Seventy two patients were included in this study. Case selection was done by non probability convenient sampling from surgical out patient department. Age of patients ranged between 15 years to 73 years. Mean age was 36.5 years with maximum prevalence in the range of 31-40 years [31.5%] Male to female ratio was 1:1.7. All patients were evaluated clinically and were advised preoperative routine investigation. All patients had voice analysis along with indirect laryngoscopic examination preoperatively. The commonest presenting complaint in 72 patients was lump front of neck in 69 [95.8%] patients, 48[66.7%] patients were having nontoxic goiter, 15 [20.8%] patients were having toxic goiter and 9 [12.5%] patients were having malignant goiter. Out of all thyroidectomies performed 48 [66.7%] were sub total, 18 [25%] lobectomy with Isthmusectomy, 5 [6.9%] were near total and 1 [1.4%] was total thyroidectomy. Temporary recurrent laryngeal nerve injury occurred in 2 [2.8%] cases. Permanent injuries to recurrent laryngeal nerve occurred in 2 [2.8%] cases, one patient had vocal cord paralysis and other developed vocal cord paresis which improved partially with time. Recurrent laryngeal nerve injury is a potentially dangerous and a serious complication of thyroid surgery. The overall percentage of injury to recurrent laryngeal nerve in thyroid surgery in this study was 4 [5.6%] cases

Resultados del tratamiento quirúrgico en el bocio endémico / Results of surgical treatment of endemic goiter

Se realiza un análisis del resultado terapéutico en la cirugía del bocio endémico sobre 77 historias clínicas actualizadas. Se obtienen conclusiones relacionadas con el procedimiento quirúrgico más adecuado, como es la lobectomía subtotal bilateral y la conveniencia de la biopsia por congelación en toda operación sobre la glándula tiroides, con el propósito de pesquisar el carcinoma oculto o inadvertido