1.
Indian Heart J
;
1997 Mar-Apr; 49(2): 152-4
Article
in English
| IMSEAR
| ID: sea-3248
ABSTRACT
This study included 54 unselected patients with rheumatic heart disease (RHD) with or without history of rheumatic fever and 224 control subjects, all Kashmiris. HLA-A19 was increased in 42.59 percent of patient population as against 23.66 percent of controls, with a relative risk of 2.39. HLA-DR4 was positive in 56 percent of patients as against 31.69 percent in controls with a relative risk of 2.74. DQ3 was also present in 72 percent of patient population as against 50.7 percent of controls. These findings suggest a genetic predisposition to rheumatic fever/RHD. More family studies are warranted.
Subject(s)
Adult , Chronic Disease , Female , Gene Frequency , HLA Antigens/immunology , HLA-A Antigens/immunology , HLA-B Antigens/immunology , HLA-C Antigens/immunology , HLA-DQ Antigens/immunology , HLA-DR Antigens/immunology , Humans , India , Male , Middle Aged , Rheumatic Heart Disease/ethnology
2.
Rev. mex. reumatol
;
8(2): 112-6, mar.-abr. 1993. ilus, tab
Article
in Spanish
| LILACS
| ID: lil-138998