Síndrome de larva migrans visceral y absceso hepático: Reporte de un caso / Visceral larva migrans syndrome and hepatic abscess: A case report

La infección por T oxocara canis o catis es una zoonosis diseminada en el ser humano. La toxocariasis puede coexistir con otras parasitosis endémicas. El hombre actúa como huésped no natural y adquiere la infección a través de la ingesta de huevos del geohelminto. Estos pueden localizarse en la tierra, los patios y los juegos de los niños, y son eliminados, principalmente, por perros o gatos. Existen distintos espectros en la presentación clínica; algunos de ellos son toxocariasis ocular, larva migrans visceral, toxocariasis encubierta y neurotoxocariasis. Se presenta el caso de un paciente de 2 años y 3 meses de edad, con antecedente de síntomas respiratorios, fiebre prolongada y hepatomegalia, con resultados de laboratorio que informa hipereosinofilia, hipergammaglobulinemia y serología positiva para toxocariasis (ensayo por inmunoabsorción ligado a enzimas). Se plantea el diagnóstico de síndrome de larva migrans visceral.

Toxocariasis canis or catis is a zoonotic infection disseminated in humans. Human beings can act as non-natural hosts in which the parasite can survive for long periods of time and they become infected by the ingestion of geohelminth eggs. These can be located on the ground, playgrounds and children's games, and are mostly eliminated by dogs or cats. There are different spectra in the clinical presentation of this infection, which can vary from an asymptomatic host to the production of serious organic lesions; some of them are ocular toxocariasis, visceral larva migrans, covert toxocariasis and neurotoxocariasis. In this case report a patient who presents with a history of respiratory problems, prolonged fever, and hepatomegaly. Laboratory analyses show hypereosinophilia, hypergammaglobulinemia and serodiagnosis is positive for toxocariasis. Preliminary diagnosis: Visceral Larva Migrans Syndrome.

Porcine abortion outbreak associated with Toxoplasma gondii in Jeju Island, Korea

This report deals with the acute onset of an abortion outbreak and high sow mortality in one pig herd consisted of 1,200 pigs and 120 sows on Jeju Island, Korea. Affected pregnant sows showed clinical signs, including high fever, gradual anorexia, vomiting, depression, recumbency, prostration, abortion, and a few deaths. Four dead sows, five aborted fetuses from the same litter, and 17 sera collected from sows infected or normal were submitted to the Pathology Division of the National Veterinary Research and Quarantine Service for diagnostic investigation. Grossly, hepatomegaly and splenomegaly were observed in sows. Multiple necrotic foci were scattered in the lungs, liver, spleen, and lymph nodes. Microscopically, multifocal necrotizing lesions and protozoan tachyzoites were present in the lesions. Tachyzoites of Toxoplasma (T.) gondii were detected immunohistochemically. Latex agglutination showed that the sera of 7 of 17 (41.2%) sows were positive for antibody to T. gondii. The disease outbreak in this herd was diagnosed as epizootic toxoplasmosis. To our knowledge, this is the first report of porcine toxoplasmosis with a high abortion rate and sow mortality in Korea.

Visceralizaçäo da leishmaniose cutâneomucosa disseminada causada pela leishmania viannia braziliensis em paciente imunocompetente / Visceralization of disseminated leishmaniosis mucocutaneous caused by leishmania viannia braziliensis in immunocompetent patient

Em relaçäo à invasäo de órgäos internos por leishmânias que normalmente se manifestam no tegumento cutâneo, foram documentados dois casos da forma tegumentar de leishmaniose com presença do parasito na medula. As espécies identificadas foram Leishmania amazonensis e Leishmania Viannia braziliensis. Relata-se o caso de um paciente de 33 anos com febre ocasional, mais de cinquenta lesoes pápuloulcerosas disseminadas na pele, infiltraçao de septo nasal, cavum, laringe e também hepatomegalia. A pesquisa de parasitos das lesöes cutâneas em cultura, no exame histopatológico e na inoculaçäo em hamsters foi positiva com a identificaçäo por anticorpos monoclonais de Leishmania Viannia braziliensis na pele. No exame histopatológico do fígado foi encontrado infiltrado histiolinfoplasmocitário com raros parasitos. O leucograma apresentou leucopenia e velocidade de hemossedimentaçäo elevada. O teste de ELISA para o vírus da imunodeficiência humana foi negativo, e testes cutâneos para avaliar imunidade celular, positivos. Este relato reforça a possibilidade de visceralizaçao, em indivíduos imunocompetentes, quando se trata de cepa de leishmania Viannia braziliensis, considerada inicialmente com tropismo exclusivo para peles e mucosas. Casos semelhantes precisam ser documentados com a identificaçäo do parasito na víscera a fim de esclarecer a patogenia dessa espécie de leishmania