ABSTRACT
We performed a thermographic study to observe any possible interaction between the esophageal acid perfusion and the temperature changes of skin surface in patients with gastroesophageal reflux disease (GERD). Twenty-seven patients with GERD were categorized as group I(globus symptoms with posterior laryngitis) and group II (heartburn and/or regurgitation symptoms). Patients and 6 healthy volunteers underwent Bernstein test (BT) and digital infrared thermographic imaging (DITI) simultaneously. The positive rate for BT in group I and group II was 22.2% and 55.6%, respectively, and the DITI positive rate was 55.6% for group I and 50.0% for group II. None of healthy control were positive in BT or DITI. All subjects with DITI positive were hypothermic. The overall accordance rate between DITI and BT was 69.7%. All group I patients showed a diffuse type, while in group 11, 4 patients showed diffuse type and 5 patients showed localized type (p<0.05). In patients with DITI (+)/BT (-), 83.3% showed diffuse type, whereas equal numbers of diffuse and localized type were noted in patients with DITI (+)/BT (+). In conclusion, add contact with a sensitive mucosa leads to an activation of the sympathetic nervous system in some patients with GERD, inducing skin surface hypothermia.
Subject(s)
Adult , Female , Humans , Male , Gastroesophageal Reflux/physiopathology , Hydrochloric Acid/administration & dosage , Image Processing, Computer-Assisted/methods , Perfusion , Skin Temperature/physiology , Thermography/methodsABSTRACT
Dicloridrato de cetirizina, novo anti-histamínico H1, foi doseado volumetricamente em meio anidro com ácido perclórico e por espectrofotometria, em 232 nm. Verificou-se que ambos os métodos säo viáveis e precisos, sendo o doseamento em meio näo-aquoso mais prático por näo requerer instrumental e ser mais rápido e fácil de executar.
Subject(s)
Drug Evaluation/methods , Cetirizine/chemistry , Acetic Acid/administration & dosage , Hydrochloric Acid/administration & dosage , Acetic Anhydrides/administration & dosage , Laboratory Chemicals , Perchlorates/administration & dosage , Quinaldines/administration & dosage , Spectrophotometry, UltravioletABSTRACT
El presente estudio se realizó en forma prospectiva en el Servicio de Endoscopia del Hospital General de México, de junio de 1983 a junio de 1984. Se encontraron 16 casos con antecedentes de ingesta de sustancias cáusticas o corrosivas y en 7 casos se documentaron hallazgos endoscópicos y/o radiológicos compatibles con gastritis cáustica, propósito especial de esta revisión. Encontramos que la gastritis cáustica en nuestro medio es poco frecuente. La relación fue semenjante para ambos sexos y el agente causal más frecuente fue el ácido clorhídrico (muriático). La causa principal fue la ingestión accidental y las edades fluctuaron de los 13 a los 84 años de edad. Los hallazgos clínicos, endoscópicos y radiológicos variaron de acuerdo al tiempo de evolución .