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1.
Bulletin of Alexandria Faculty of Medicine. 1995; 31 (3): 473-84
in English | IMEMR | ID: emr-36658

ABSTRACT

Two groups of albino rats were included. The control group is formed of nine albino rats, divided into three subgroups: 1] Primed [sensitized] only by intraperitoneal injection of soybean protein emulsion, 2] duodenal tube feeding for 14 days by soybean protein hydrolysate only, and 3] oral feeding by soybean protein-free milk formula. The test group formed of nine albino rats were primed by intraperitoneal injection of soybean protein emulsion and challenged after one week by duodenal tube feeding of soybean protein hydrolysate for 14 days or till diarrhea developed. Results showed that all control groups showed no pathological abnormalities in their duodenum and did not develop diarrhea. The test group showed basically similar changes that varied in severity from mild, moderate to marked. The immunological findings were humoral and cellular immume reaction. Edema of the duodenum erythema and reduction in the size of the villi were seen morphologically. Ultrastructurally, deposition of immune complexes in the basement membrane leading to its thickening and irregularity, adhesion of leukocytes [PNLs, monocytes and lymphocytes] to the injured endothelium, edematous corium and inflammatory cellular infiltrate, increase in the number of lymphocytes going to the surface and congested plugged blood vessels were seen


Subject(s)
Animals, Laboratory , Hypersensitivity/diet therapy , Duodenitis , Glycine max , Immunoglobulin E , Duodenum/ultrastructure , Duodenum/physiopathology
2.
Alergia (Méx.) ; 41(1): 9-13, ene.-feb. 1994. tab
Article in Spanish | LILACS | ID: lil-135208

ABSTRACT

Se estudiaron 30 embarazadas, de las que 20 tenían una historia clínica y datos de laboratorio y pruebas cutáneas necesarios para diagnosticarlas como atópicas. Diez de las embarazadas atópicas estuvieron bajo una dieta de exclusión a partir del segundo trimestre del embarazo, y las otras diez siguieron una dieta normal. Como grupo testigo se incluyeron 10 embarazadas no atópicas. Cada uno de los productos del embarazo se estudió y siguió hasta por 12 meses, haciéndose una cuantificación de IgE dentro de los primeros dos meses de edad. Los resultados clínicos sugieren que una dieta apropiada durante el embarazo en las mujeres atópicas disminuye el riesgo de que sus hijos tengan cuadros alérgicos en los primeros 12 meses de vida, ya que los hijos de las mujeres que siguieron la dieta de eliminación tuvieron un menor número de problemas alérgicos, en comparación con las que llevaron una dieta normal (dos casos contra cinco, respectivamente) y ninguna enfermedad alérgica en el grupo testigo


Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Infant , Hypersensitivity/diet therapy , Pregnancy Tests, Immunologic/statistics & numerical data , Pregnancy Trimester, First/immunology , Hypersensitivity/genetics , Immunoglobulin E/genetics
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