ABSTRACT
We present a case of a 20 years old woman who consults for amenorrhea and mild hyperprolactinemia. Within the functional study hypopituitarism was discover and MRI showed a cystic lesion with ring enhancement. Transsphenoidal resection was performed, showing purulent material. Cultures were positive for MSSA and Neisseria cinerea. Antibiotic treatment was started completing 21 days. She evolved without relapse but did not recovered pituitary function.
Subject(s)
Humans , Female , Young Adult , Abscess/surgery , Abscess/diagnosis , Hypopituitarism/surgery , Hypopituitarism/diagnosis , Abscess/drug therapy , Anti-Bacterial Agents/therapeutic use , Hypopituitarism/drug therapy , Neisseria cinerea/isolation & purificationABSTRACT
Lymphocytic hypophysitis (LH) is an uncommon inflammatory disease of the hypophysis. It's female to male ratio of appearance is 9:1. Pregnant women are more affected during the third trimester of pregnancy or postpartum. Clinical and radiological presentation can simulate a hypophyseal adenoma. We report a nonpregnant 13 years old adolescent, with a trisomy 12p, with panhypopituitarism, diabetes insipidus and a selar tumor. It was necessary to differentiate between a germinoma and a LH. The latter was confirmed with the hypophyseal biopsy.