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1.
Braz. J. Pharm. Sci. (Online) ; 58: e181053, 2022. tab
Article in English | LILACS | ID: biblio-1360163

ABSTRACT

Abstract The effect of hypothermia treatment on white blood cell (WBC), neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR) and platelet-to-lymphocyte ratio (PLR) values as an indicator of inflammation was evaluated in newborns with hypoxic ischemic encephalopathy (HIE). The study was performed that the before-therapeutic hypothermia (TH) and after-TH WBC, lymphocytes, neutrophils, monocytes and NLR, LMR and PLR values of the complete blood cell count were retrospectively evaluated. The results of the patient group were compared with the results of healthy newborns. A total of 78 patients who underwent TH were evaluated in our study. Mean values before and after TH were NLR3.8/2.7, LMR 5.6/8.6, and PLR 60.3/67.1 respectively. A statistical significance was present for NLR values before and after TH in those with seizure in our study (4.15±2.95/3.01±2.54) but no statistical significance was found for LMR or PLR. In neonates with HIE, effect of TH on complete blood cell count and inflammatory mechanisms (mediated neutrophil and lymphocyte) may be minimal.


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant, Newborn/physiology , Hypoxia-Ischemia, Brain/pathology , Hypothermia/pathology , Blood Cell Count/methods , Hypothermia/classification , Inflammation
2.
León; s.n; mar. 2006. 36 p. tab.
Thesis in Spanish | LILACS | ID: lil-592977

ABSTRACT

El documento presenta un estudio de ensayo clínico realizado en el Servicio de Anestesiología del Hospital Escuela "Dr. Oscar Danilo Rosales Argüello" en Sala de Operaciones (Quirófanos), la población de estudio fue de 108 pacientes progrmados para cirugía abdominal elecctiva, durante el periodo de marzo a noviembre del año 2005. Para el estudio se aplicaron criterios de inclusión como: Pacientes con ASA I - II, Pacientes programados para cirugía abdominal electiva bajo anestesía general, edad de 20 a 60 años. Se realizó a dos grupos de la siguiente forma: 1 er grupo se le denominó (Control) al que se le hizo diagnóstico de Hipotermia Introperatoria: 2 do. Grupo Experimental Intervención donde se hicieron medidas prevención de Hipotermia Intraoperatoría. El estudio a permitido conocer que los pacientes sometidos a cirugía electiva sin medidas de prevención de hipotermia intraoperatoria y que superaron las dos horas quirúrgicas presentaqron hipotermia intraoperatoria de forma gradual, con perdida de la temperatura corporal de 0.5 grado c- 15 grado c durante la primera hora de cirugía...


Subject(s)
Body Temperature , Hypothermia/classification , Hypothermia/diagnosis , Hypothermia/etiology , Monitoring, Intraoperative/statistics & numerical data , Hypothermia/surgery , Hypothermia/pathology , Hypothermia/prevention & control
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