ABSTRACT
Os efeitos positivos da fibra alimentar estão relacionados, em parte, ao fato de que uma parcela da fermentação de seus componentes ocorre no intestino grosso, o que produz impacto sobre a velocidade do trânsito intestinal, sobre o pH do cólon e sobre a produção de subprodutos com importante função fisiológica. Indivíduos com elevado consumo de fibras parecem apresentar menor risco para o desenvolvimento de doença coronariana, hipertensão, obesidade, diabetes e câncer de cólon. O aumento na ingestão de fibras reduz os níveis séricos de colesterol, melhora a glicemia em pacientes com diabetes, reduz o peso corporal e foi associado com menores níveis séricos de proteína C reativa ultrassensível. O maior consumo de fibras e a ingestão de mais fibras do que a atualmente recomendada (14 g/1.000 kcal) poderão trazer maior benefício à saúde, incluindo a redução de processos inflamatórios de baixo grau.
The positive effects of dietary fiber are related, in part, to the fact that a portion of the fermentation of components takes place in the large intestine, which has an impact on the speed of digestion, pH of the colon, and production of by-products with important physiological functions. Individuals with high fiber intake seem to have lower risk of developing coronary artery disease, hypertension, obesity, diabetes, and colon cancer. The increase in fiber intake reduces serum cholesterol, improves blood glucose in patients with diabetes, reduces body weight, and is associated with lower serum ultrasensitive C-reactive protein. Increased fiber intake and intake of more fiber than the currently recommended level (14 g/1,000 kcal) may provide greater health benefits, including reducing low-grade inflammation.
Subject(s)
Humans , Blood Glucose/metabolism , Diabetes Mellitus/prevention & control , Dietary Fiber/administration & dosage , C-Reactive Protein/analysis , Chronic Disease , Cardiovascular Diseases/prevention & control , Cholesterol/blood , Constipation/prevention & control , Inflammation/prevention & control , Intestinal Neoplasms/prevention & control , Intestines/microbiology , Intestines/physiology , Obesity/prevention & controlABSTRACT
Freqüentemente nas manchetes de jornais, assim como na literatura científica, focaliza-se o aumento do número de casos de câncer nos últimos anos. Dentre as variadas localizações, estatísticas do Ministério da Saúde ( DATASUS/ 2001 ) apontam o câncer colorretal como um dos que apresentam maior incidência de novos casos a cada ano. Programas de Assistência a Ostomizados foram traçados pelas bases governamentais e, cada vez mais, nos deparamos com este tipo de patologia no ambiente hospitalar. Na prática, porém, observa-se que a grande maioria dos profissionais de saúde não está preparada psico-sócio-emocionalmente para assistir a este tipo de clientela. Sendo assim, o presente estudo tem por objetivo discutir as condições nas quais estes se encontram no desempenho de suas atividades, frente ao cliente mutilado por uma ostomia intestinal. Problemas e propostas foram levantadas no decorrer do estudo, com o intuito de conscientizar os gestores hospitalares da real situação em que se encontram estes profissionais, sua qualidade de vida e como ocorre a influência destes fatores na assistência prestada ao cliente ostomizado que se encontra hospitalizado
Subject(s)
Enterostomy , Intestinal Neoplasms/prevention & controlABSTRACT
Probiotics are described as live microbial food ingredients that are beneficial to health of the of host, especially by improving intestinal microbial balance. The major consumption of probiotics is in dairy-based foods form, which is containing intestinal species of Lactobacillus and Bifidobacterium. A number of potential benefits of probiotics have been proposed, including: adherence to cells; exclusion or reduction of pathogenic adherence; production of acids, hydrogen peroxide, and bacteriocins antagonistic to pathogen growth; safe, noninvasive, noncarcinogenic and nonpathogenic characteristics; and congregation to form a normal balanced flora. The interrelation between probiotics and health are reviewed in this article.
Subject(s)
Humans , Intestinal Neoplasms/prevention & control , Probiotics/administration & dosageABSTRACT
Wistar male rats, 3 months of age were given ad-libitum a nutritionally adequate diet and demineralized drinking water. The Molybdenum (Mo) and Tungsten (W) were provided in the drinking water at 200 ppm concentration. Intestinal tumors were induced by 1,2-dimethylhydrazine (DMH) given subcutaneously as 16 weekly doses at 20 mg/kg body weight. Mo in the form of (NH4)6 Mo7O24 4H2O or W in the form of (Na2WO4) were provided in the drinking water two months before the first DMH treatment and were continued during 4 months more until the last DMH treatment. Three months after the last carcinogen injection, all animals were sacrificed and examined for intestinal tumors. The number, size and location of the tumors were recorded and the pathology was examined. The addition of Mo to the drinking water induced an increase of hepatic Mo content. At the end of the second month, the hepatic content of Mo was 5.61 ppm, compared with control and W groups (2.18 and 0.96 ppm, respectively). A significantly lower incidence of tumors was observed in the Mo group (47), compared with the control group given DMH alone (105) and W group (113). On the other hand, the Mo group showed a significant decrease in the numbers of multiple tumors per rat.