ABSTRACT
El presente trabajo tiene el objetivo de mostrar los efectos de la Calendula officinalis en preparación homeopática sobre las lesiones características de la queratosis seborreica, en una muestra piloto, de tipo clínico, conformada por ocho pacientes del sexo femenino, cuyo rango de edad se encuentra entre los 52 y 76 años. Las voluntarias fueron captadas en la Unidad Médica de la Escuela Nacional de Medicina y Homeopatía del Instituto Politécnico Nacional. La elección de la calendula officinalis como tratamiento fue sustentada por antecedentes de estudios realizados sobre la misma, los cuales demostraron una acción antitumoral.
This paper aims to show the effects of Calendula officinalis in homeopathic preparation on the characteristic lesions of seborrheic keratosis, a pilot sample, clinical, composed of eight female patients whose age range is between 52 and 76 years. The volunteers were captured in the Medical Unit of the National School of Medicine and Homeopathy , National Polytechnic Institute . The choice of calendula officinalis and treatment was supported by a history of studies of the same , which showed an antitumor action.
Subject(s)
Humans , Female , Middle Aged , /therapeutic use , Keratosis, Seborrheic/therapy , Homeopathic Therapeutics , Homeopathic Pharmacy Techniques , Treatment OutcomeABSTRACT
La queratosis seborreica clonal es una variante histológica rara de queratosis seborreica. Se informa sobre una paciente de sexo femenino, de 87 años de edad, que acudió a consulta de dermatología por presentar lesión tumoral única, de 10 centímetros de diámetro, localizada en abdomen, de 40 años de evolución y crecimiento lento, asociada a intenso prurito. Se diagnosticó clínicamente queratosis seborreica gigante y, desde el punto de vista histopatológico, una variante clonal. Se realizó extirpación quirúrgica de la lesión, con resultados satisfactorios.
Clonal seborrheic keratosis is a rare histological type of seborrheic keratosis. An 87 year-old female patient is presented that came for dermatology consultation due to a lone tumoral lesion, 10 cm in diameter, located in the abdomen, with 40 years of slow growth, associated to intense pruritus. It was clinically diagnosed as giant seborrheic keratosis, and the biopsy showed clonal variant. She had surgical extirpation of the lesion with satisfactory results.
Subject(s)
Humans , Female , Aged , Skin Diseases , Keratosis, Seborrheic , Keratosis, Seborrheic/etiology , Keratosis, Seborrheic/therapyABSTRACT
BACKGROUND: Topical anesthesia for skin surgery has widely been used for a long time. Various preparations are used. The EMLA cream is the most popular one. OBJECTIVE: The authors compared the local analgesic effect of topical lidocaine iontophoresis and EMLA cream in a crossover study design. METHOD: After informed consent, 16 patients with seborrheic keratosis, who required CO2 laser surgery, were enrolled. Two lesions on the opposite side of the body with a comparable size, shape and location were selected from each patient. The lidocaine iontophoresis was done on one lesion and the EMLA cream was applied on the other The CO2 laser surgery was performed after 10 min of lidocaine iontophoresis and 60 min after EMLA cream. The level of pain was recorded using a 100-mm visual analog scale. Ratings of patient satisfaction were also assessed. RESULTS: There were no significant differences in pain scores between the two groups (p=0.968), but significantly higher in satisfaction scores (1-5 scale) in the iontophoretic group than the EMLA group (p=0.005). Fifteen patients preferred lidocaine iontophoresis (93.8%), none preferred EMLA cream. All patients in the present study tolerated the tingling and burning sensations. No severe adverse events and side effects were detected. CONCLUSION: Lidocaine iontophoresis provides effective pain relief for CO2 laser surgery of seborrheic keratosis as well as the EMLA cream. The effect is as fast as 10 min after application. There is no significant side effect. Most of the patients were satisfied. Lidocaine iontophoresis is a useful, noninvasive local anesthesia for CO2 laser surgery of superficial skin lesions.