ABSTRACT
This formulated product as composed of the necessary amounts of pyrethroids and the required amount of the Kerosine caused severe, unacceptable pathological developmental changes. Body weight of newborns showed progressive affection of the newly born, of which Kerosine has marked influence. Mother behaviour was studied from quality of nest, post parturient aggressive interest of mother towards their youngsters were found to be significantly affected. Male sexual activity was revealed from weight of testis or accessory organs and semen quality. Kerosine alone induced significant differences. Estrous cycle was affected and regressive activity prolonged whatever the animal is exposed. Number of dead and resorbed foeti was significantly different in Kerosine and the whole compound. Teratogenic affection of the born foeti were clear even with Kerosine alone and absence of accessory elements [thymus gland]. Thus, this formulation is described as being severely hazardous and care should be taken even with the manipulation of Kerosine alone
Subject(s)
Male , Female , Animals, Laboratory , Kerosene/adverse effects , Rats , Aggression , Mortality , Teratogens , Fetal Resorption , Liver/pathology , Adrenal Glands/pathology , Histology , Brain/pathology , Ovary/pathology , Insecticides/toxicitySubject(s)
Humans , Male , Kerosene/adverse effects , Self Mutilation , Self-Injurious Behavior , Skin TransplantationABSTRACT
This study documents 3-year retrospective analysis of accidental kerosene oil poisoning in 70 children with regard to clinical profile, radiological changes and outcome. About 77% of cases were between 1 and 3 years old. Fifty children (71.4%) developed significant symptoms, with onset soon after to within 10 hours of ingestion. These included breathlessness (55.7%), fever (47.1%), cough (31.4%), restlessness (25.7%) and abdominal distension (15.7%). Chest X-rays were obtained in 65 children. Abnormal radiographs were seen in 45 (69.2%) children with right basal infiltrates being the commonest picture (21.4%). Ingestion of more than one ounce of kerosene oil adversely affected the clinical and radiological profile. Severely malnourished children had extensive radiological changes and poorer clinical outcome. One case developed myocarditis, a complication which has not been reported to the best of our knowledge. Mortality rate was 4.3%. All deaths occurred within 48 hours of admission.
Subject(s)
Accidents, Home , Child, Preschool , Female , Health Promotion , Humans , India , Infant , Kerosene/adverse effects , Male , Mortality , Radiography , Respiratory Insufficiency/diagnosis , Retrospective StudiesABSTRACT
Se estudia el efecto del aerosol de queroseno sobre el metabolismo de los lìpidos en la rata. Se utilizaron ratas de las líneas Wister e INOR y recibieron tratamiento una hora diaria durante 30 días. Los controles recibieron aerosol de suero fisiológico en la misma forma. Se midieron los lípidos del plasma. Se extrajeron y cuantificaron los lípidos del pulmón, hígado y aorta. No se observaron diferencias significativas en las concentraciones de los lìpidos del plasma ni en las de los tejidos. Macroscópicamente no se observaron placas ateromatosas en las aortas. Los animales mostraron un decremento significativo de la ganancia de peso