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Indian J Dermatol Venereol Leprol ; 2006 Sep-Oct; 72(5): 376-8
Article in English | IMSEAR | ID: sea-52233

ABSTRACT

A 45-year-old male presented with asymptomatic tumors all over the body. The tumors showed no signs of ulceration or regression. There were generalized, nontender, firm to hard enlarged lymph nodes without hepatosplenomegaly. Biopsy and immunophenotyping revealed CD 30+ anaplastic primary cutaneous large cell lymphoma. Primary cutaneous anaplastic large cell lymphoma is characterized by single or grouped reddish-brown tumor nodules, which frequently tend to ulcerate. Secondary involvement of lymph nodes is seen in only 25%. The lesions responded dramatically to chemotherapy, but recurred.


Subject(s)
Ki-1 Antigen/biosynthesis , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Cyclophosphamide/therapeutic use , Doxorubicin/therapeutic use , Humans , Lymphoma, Large B-Cell, Diffuse/diagnosis , Male , Middle Aged , Prednisone/therapeutic use , Skin Neoplasms/diagnosis , Vincristine/therapeutic use
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