ABSTRACT
Abstract: Primary localized cutaneous amyloidosis is a skin-limited amyloidosis that does not involve internal organs. It is clinically subclassified into 3 general categories and some rare variants. However, there is considerable overlap within the classification. Though there are a variety of therapeutic measures, the treatment is often unsatisfactory, particularly when the disease is severe and extensive. We describe a rare case of primary localized cutaneous amyloidosis with lichen and poikiloderma-like lesions that showed an excellent response to systemic acitretin.
Subject(s)
Humans , Female , Young Adult , Skin Diseases, Genetic/drug therapy , Acitretin/therapeutic use , Amyloidosis, Familial/drug therapy , Keratolytic Agents/therapeutic use , Skin Diseases, Genetic/complications , Skin Diseases, Genetic/diagnosis , Treatment Outcome , Lichenoid Eruptions/complications , Lichenoid Eruptions/drug therapy , Amyloidosis, Familial/complications , Amyloidosis, Familial/diagnosisSubject(s)
Aged , Drug Eruptions/complications , Humans , Lichenoid Eruptions/complications , Male , Nail Diseases/complicationsABSTRACT
Cutaneous tuberculosis may be associated with concurrent systemic foci in the body such as lung, lymph node, bone or CNS. Phlyctenular keratoconjunctivitis (PKC) is a manifestation of immunological response to a variety of antigens in the eye, tubercular focus (evident or occult) being the commonest in India. Reports in the existing literature have shown lungs and lymph nodes to be the predominant underlying focus associated with PKC, whereas cutaneous tuberculosis has seldom been found in this situation. We report this forgotten association in two children with cutaneous tuberculosis, one each with lupus vulgaris and scrofuloderma, who also had PKC. Interestingly, one of the cases also had simultaneous lichen scrofulosorum, which is also an immunological response to tubercular antigen and manifests in the skin, thus showing immunological manifestation in two different organ systems along with cutaneous focus of tuberculosis.
Subject(s)
Child , Female , Humans , Keratoconjunctivitis/complications , Lichenoid Eruptions/complications , Lupus Vulgaris/complications , Male , Tuberculosis, Cutaneous/complications , Tuberculosis, Pulmonary/diagnosisABSTRACT
Os autores apresentam um caso de erupçäo liquenóide desencadeada sete dias após o início do uso de nortriptilina e realizam uma revisäo de literatura, na qual näo foram encontrados relatos desta associaçäo. É ressaltada a necessidade dos médicos, em particular, dos dermatologistas manterem atençäo permanente para possíveis novas associaçöes causais entre uma fármaco e determinado quadro clínico cutâneo.
Subject(s)
Humans , Female , Adult , Antidepressive Agents, Tricyclic/adverse effects , Antidepressive Agents, Tricyclic/pharmacology , Antidepressive Agents, Tricyclic/therapeutic use , Lichenoid Eruptions/complications , Lichenoid Eruptions/diagnosis , NortriptylineABSTRACT
La liquenificación gigante de Pautrier es una forma rara y exhuberente de liquen simple crónico que resulta del rascado intenso de zonas intertriginosas tales como genitales, ingles y axilas. Presentamos un caso de esta rara afección en el que las lesiones aparecían ulceradas haciendo de esta manera difícil el diagnóstico