ABSTRACT
O objetivo desse estudo é descrever uma criança com lipossarcoma periorbital, caracterizando seus aspectos clínico-epidemiológicos e terapêuticos. Menina de 6 meses de idade com tumoração crescente há dois meses em região fronto-zigomática direita, a qual foi submetida à exérese e cujas análises anatomopatológica (AP) e imuno-histoquímica (IH) observaram achados típicos de lipoblastoma. Após isso, apresentou mais três recidivas tumorais com diagnósticos similares. Um ano depois da última cirurgia, houve nova recorrência, porém, dessa vez, o resultado dos exames análises anatomopatológica e imuno-histoquímica foi de lipossarcoma, sendo, então, encaminhada para complementar o tratamento com radio e quimioterapia, sem novas lesões até o momento. Devido a sua raridade, geralmente o lipossarcoma não entra no diagnóstico diferencial em pacientes com massas orbitais, porém, por ser localmente agressivo, torna-se vital a pronta identificação e tratamento de forma a oferecer melhores resultados terapêuticos e influência sobre a qualidade de vida do paciente.
The purpose of this study is report a child with periorbital liposarcoma describing the clinical, epidemiological and therapeutic aspects. Six-months-old female baby with increasing tumor in the right fronto-zigomatic region wich was submitted to excision and the patologic and immunohistochemistry analisys observed typical findings of lipoblastoma. After that, there were three tumors relapse with the same diagnosis. One year after the last surgery there was a recurrence of the tumor but at this time the diagnosis was lipossarcoma and the patient was referred for additional treatment wilth radiotherapy and chemotherapy no new injuries so far Due to its rarity, liposarcoma usually does not enter the differencial diagnosis in the patients with orbital masses, however because of its local aggressiveess, it's vital the early identification and treatment to provide better therapeutic results and quality of life.
Subject(s)
Female , Humans , Infant , Liposarcoma/pathology , Orbital Neoplasms/pathology , Diagnosis, Differential , Liposarcoma/therapy , Neoplasm Recurrence, Local/pathology , Neoplasm Recurrence, Local/therapy , Orbital Neoplasms/therapy , Reoperation , Treatment OutcomeABSTRACT
Introduction: Liposarcomas are neoplasms of mesodermal origin derived from adipose tissue and correspond to 10-14of all soft tissue sarcomas. Paratesticular liposarcoma is very rare. Case report: We report a 60-year old man who presented with a left testicular tumor 20 cm in diameter. Initial incisional biopsy was reported as fibromatosis. Chest and abdominal CT scan did not show distant metastases. Through an inguinal incision orchidectomy with homolateral inguinal node dissection was performed. Histopathological examination showed a paratesticular myxoid liposarcoma. Adjuvant radiotherapy without chemotherapy was administered. The patient remains well at 11 months followup; with no evidence of recurrence. Conclusion: Complete surgical extirpation reduces the risk of local recurrence. Neoadjuvant chemotherapy or radiotherapy may reduce the tumor size; thus facilitating complete excision
Subject(s)
Liposarcoma , Liposarcoma/therapy , Middle Aged , Testicular NeoplasmsABSTRACT
Relatamos o caso de uma mulher de 51 anos com lipossarcoma mediastinal. O lipossarcoma é a neoplasia mesenquimal maligna mais comum em adultos, embora sua localização mediastinal seja extremamente rara. Ele possui grande volume e variados subtipos histológicos. É caracterizado pela compressão de estruturas vizinhas. A tomografia computadorizada e a ressonância magnética fornecem informações úteis para o diagnóstico.A biopsia tecidual e a identificação do tipo histológico são importantes na determinação da terapia e são necessárias para o diagnóstico final. A radioterapia e a quimioterapia são modalidades terapêuticas ineficazes. De acordo com a literatura, a ressecção cirúrgica é o tratamento de escolha. Está indicado o acompanhamento a longo prazo, pois a taxa de recidiva é alta.
Here, we describe the case of a 51-year-old female with mediastinal liposarcoma. Liposarcoma is the most common malignant mesenchymal neoplasm in adults, although a mediastinal location is extremely rare. It has a large volume and varied histologic subtypes. It is characterized by the compression of neighboring structures. Computed tomography and magnetic resonance imaging provide useful data for diagnosis. Tissue biopsy and histological typing are very important in determining the treatment and are needed for the final diagnosis. Radiotherapy and chemotherapy are ineffective treatment modalities. According to the literature, surgical resection is the treatment of choice. Long-term follow-up evaluation is indicated since there is a high rate of recurrence.
Subject(s)
Female , Humans , Middle Aged , Liposarcoma/diagnosis , Mediastinal Neoplasms/diagnosis , Chemotherapy, Adjuvant , Liposarcoma/therapy , Magnetic Resonance Spectroscopy , Mediastinal Neoplasms/therapy , Radiotherapy, AdjuvantABSTRACT
Cardiac tumors are rare. In autopsic series, their incidence is 0.02 - 0.03%. Liposarcoma is an exceptionnel cause of cardiac metastasis. We report the case of a 55 years old patient, operated for multiple localisations of liposarcoma [left leg, left arm, abdomen]. As well as, he has a vertebral metastasis treated by radiotherapy. Two months later, the patient consulted for dyspnoea. A cardiac ultrasound tomography showed dilated right cavities with a volumineous intra ventricular mass. A thoracic computed tomography was showed a tissular intracardiac mass. The patient was operated in a cardiovascular surgery service, but died in post operative period. The purpose of this study is to specify the cardiac metastasis incidence, the diagnostic methods and therapic modalities
Subject(s)
Humans , Male , Myocardium/pathology , Neoplasm Metastasis , Leg/pathology , Liposarcoma/therapyABSTRACT
6 cases of R.P.L.S traited in the service of surgery B at Ibn Sina hospital, were reviewed, It was a big tumors [more than 6 Kg]. The C.T scan can gives the diagnosis of both localization and histology of tumor respectively in 90% and 40%. Cytoponction guided by echography can make diagnosis but there are move false negative. Histological examination is difficult there was more stage I in our study. The treatment of R.P.L.S is based on tumoral excision, which is often possible in spite of the great volume of tumor. One or more recurences were noted in 3 cases often in high grade of malignancy with lymphatic noeds and invasion of other organs. the use of radiotherapy can't ovoid this recurences. The survival rate was: -1 patient died at 4th year -2 were not seen after 3th an 5th years - 3 others were alive at 6 months, 1 year and 22 months
Subject(s)
Humans , Male , Female , Retroperitoneal Neoplasms , Liposarcoma/therapyABSTRACT
Os autores apresentam a experiência da Clínica de Cirurgia Vascular do Hospital Naval Marcílio Dias na utilizaçäo das embolizaçöes terapêuticas em 12 pacientes portadores de patologias diversas. Dos doze pacientes, dez apresentaram bons resultados, em um o resultado foi considerado regular e em um o resultado foi considerado ruim. A complicaçäo mais séria consistiu em necrose isquêmica do colo direito após embolizaçäo de angiodisplasia. Os autores concluem que as E.T. constituem um método de grande valia em casos críticos onde a aplicaçäo dos procedimentos convencionais fica prejudicada
Subject(s)
Child , Adult , Middle Aged , Humans , Male , Female , Carcinoma, Squamous Cell/therapy , Epidermal Cyst/therapy , Embolization, Therapeutic , Gastrointestinal Hemorrhage/therapy , Hemangioma/therapy , Hemoptysis/therapy , Kidney Neoplasms/therapy , Liposarcoma/therapy , Neck Dissection , Liver Neoplasms/therapy , Wounds, Gunshot/therapyABSTRACT
Los liposarcomas son tumores poco frecuentes cuya localización ocurre predominantemente en las extremidades. Puede hallárselos también en el retroperitoneo. El hallazgo de liposarcoma en un órgano específico es de extrema rareza. La revisión de literatura indica la ocurrencia de un sólo caso localizado en el páncreas