Rattus norvegicus infectados com Trypanosoma cruzi: efeitos clínicos do tratamento com Lycopodium clavatun e phosphorus ultradiluídos / Rattus norvegicus infected with Trypanosoma cruzi: clinical effects of treatment with highly diluted Lycopodium clavatun and phosphorus / Rattus norvegicus infectado con Trypanosoma cruzi: efectos clínicos del tratamiento con Clavatun licopodio altamente diluido y fósforo

A doença de Chagas causada pelo parasita Trypanosoma cruzi acomete milhões de pessoas no mundo e não conta com um medicamento de ação efetiva para o seu tratamento etiológico. As drogas disponíveis, o nifurtimox e o benznidazol possuem índices de cura baixos com efeitos colaterais e toxidade que dificultam a adesão dos pacientes à terapia. Este fato impulsiona a busca por alternativas de tratamento que sejam mais efetivas e menos agressivas. Sendo assim, este trabalho teve como objetivo a avaliação dos efeitos clínicos apresentados por Rattus norvergicus infectados por T. cruzi e tratados com soluções ultradiluídas de Lycopodium clavatum ou Phosphorus. O estudo envolveu 93 ratos com quarenta e cinco dias de idade infectados intraperitonealmente com 5x106 formas tripomastigotas sanguíneos da cepa Y de T. cruzi, distribuídos nos grupos: Sadio SD (n=13) - controle não infectado e não tratado, grupo CI (n=27) - controle infectado e tratado com solução hidroalccólica 7% (etanol ­ água), grupo LY diluição 1:1x1026 (n=27) - infectado e tratado com Lycopodium, grupo PH diluição 1:1x1026 (n=26) - infectado e tratado com Phosphorum. Os animais foram avaliados clinicamente através dos parâmetros peso, temperatura, consumo de água e ração, quantidade de excretas, diâmetro e comprimento intestinal, aspecto da pelagem e consistência das fezes. Este estudo mostrou que os parâmetros utilizados foram importantes para a definição clínica da infecção de Rattus novergicus, linhagem Wistar pelo T. cruzi. Mostrou que os medicamentos LY e PH apresentam efeitos benéficos na evolução da clínica dos animais tratados. A utilização de Lycopodium clavatum e Phosphorus diluídos na proporção de 1:1x1026, apresentaram efeitos diferentes. Oito e seis parâmetros de quatorze analisados mostraram efeitos positivos para LY e PH, respectivamente. Os parâmetros consumo de água e ração, quantidade de excretas, diarreia, alopecia difusa e comprimento intestinal apresentaram diferenças significativas em relação ao controle infectado mostrando que mais estudos são necessários com o uso de medicamentos ultradiluídos na infecção pelo T. cruzi.

Chagas disease caused by the parasite Trypanosoma cruzi affects millions of people worldwide and does not have an effective drug for its etiological treatment. The available drugs, nifurtimox and benznidazole, have low cure rates with side effects and toxicity that make it difficult for patients to adhere to therapy. This fact drives the search for treatment alternatives that are more effective and less aggressive. Therefore, this work aimed to evaluate the clinical effects presented by Rattus norvergicus infected by T. cruzi and treated with ultradiluted solutions of Lycopodium clavatum or Phosphorus. The study involved 93 forty five day old rats intraperitoneally infected with 5x106 blood trypomastigotes forms of the Y strain of T. cruzi, distributed in the following groups: Healthy SD (n=13) - non-infected and untreated control, CI group (n =27) - infected control and treated with 7% hydroalcoholic solution (ethanol ­ water), LY group dilution 1:1x1026 (n=27) - infected and treated with Lycopodium, PH group dilution 1:1x1026 (n=26) - infected and treated with Phosphorum. The animals were clinically evaluated through the parameters weight, temperature, water and feed consumption, amount of excreta, intestinal diameter and length, coat appearance and feces consistency. This study showed that the parameters used were important for the clinical definition of infection of Rattus novergicus, Wistar lineage by T. cruzi. It showed that LY and PH drugs have beneficial effects on the clinical evolution of treated animals. The use of Lycopodium clavatum and Phosphorus diluted in the ratio of 1:1x1026, showed different effects. Eight and six parameters out of fourteen analyzed showed positive effects for LY and PH, respectively. The parameters water and feed consumption, amount of excreta, diarrhea, diffuse alopecia and intestinal length showed significant differences in relation to the infected control, showing that more studies are needed with the use of ultradiluted drugs in T. cruzi infection.

La enfermedad de Chagas causada por el parásito Trypanosoma cruzi afecta a millones de personas en todo el mundo y no cuenta con un fármaco eficaz para su tratamiento etiológico. Los fármacos disponibles, nifurtimox y benznidazol, presentan bajas tasas de curación con efectos secundarios y toxicidad que dificultan la adherencia terapéutica de los pacientes. Este hecho impulsa la búsqueda de alternativas de tratamiento más eficaces y menos agresivas. Por lo tanto, este trabajo tuvo como objetivo evaluar los efectos clínicos presentados por Rattus norvergicus infectados por T. cruzi y tratados con soluciones ultradiluidas de Lycopodium clavatum o Fósforo. En el estudio participaron 93 ratas de cuarenta y cinco días de edad infectadas intraperitonealmente con 5x106 formas tripomastigotes sanguíneas de la cepa Y de T. cruzi, distribuidos en los siguientes grupos: SD sano (n=13) - control no infectado y no tratado, grupo CI (n =27) - control infectado y tratado con solución hidroalcohólica al 7% (etanol - agua), grupo LY dilución 1:1x1026 (n=27) - infectado y tratado con Lycopodium, grupo PH dilución 1:1x1026 (n=26) - infectado y tratado con Phosphorum. Los animales fueron evaluados clínicamente mediante los parámetros peso, temperatura, consumo de agua y pienso, cantidad de excrementos, diámetro y longitud intestinal, aspecto del pelaje y consistencia de las heces. Este estudio demostró que los parámetros utilizados eran importantes para la definición clínica de la infección de Rattus novergicus, linaje Wistar por T. cruzi. Demostró que los fármacos LY y PH tienen efectos beneficiosos en la evolución clínica de los animales tratados. El uso de Lycopodium clavatum y Phosphorus diluidos en la proporción de 1:1x1026, mostró efectos diferentes. Ocho y seis parámetros de los catorce analizados mostraron efectos positivos para LY y PH, respectivamente. Los parámetros consumo de agua y pienso, cantidad de excretas, diarrea, alopecia difusa y longitud intestinal mostraron diferencias significativas en relación al control infectado, mostrando que son necesarios más estudios con el uso de fármacos ultradiluidos en la infección por

Lycopodium clavatum as a homeopathic treatment in Magellanic penguins (Sphenicus magellanicus)

Uric acid is the main form of excretion of nitrogenous components in birds. The assessment verification samples, control, check of uric acid concentrations is widely used to detect kidney disease. High concentrations (up to five times) of uric acid in plasma can lead to the precipitation of this acid in the form of crystals, which accumulate in the tissues, mainly in the synovial joints and the viscera surface. Aims: report the evolution of homeopathic treatment in increased uric acid in Magellanic penguins (Spheniscus magellanicus) from Santo André Municipal Zoo. Methodology: 12 animals showed an increase in uric acid (reference values 0,3-16,1mg/dL) and received homeopathic treatment with Lycopodium clavatum 6cH. The protocol established was the administration of two globules of Lycopodium clavatum 6cH, once a day, inside fishes offered in the animal's beak. Treatment started on 25/09/2019. On 30/10/2019 was collected a new blood sample, those who were not discharged were kept on treatment and new collections were made on 27/11/2019 and 17/12/2019. Results: 8 animals had an average uric acid of 20.45mg /dl and responded to the 35-days treatment, normalizing the biochemical values with an average of 12.24mg /dl. Two animals with 18.27 mg /dl were discharged in 62 days with 11.70 mg /dl and another two penguins with 19.85 mg /dl were discharged in 82 days later with 9.57 mg /dl of uric acid. Conclusion: Homeopathy proved to be successful in the treatment of increased uric acid in Magellanic penguins, easy to administer, affordable and without side effects.

Management of early years of simple and mucopurulent chronic bronchitis with pre-defined Homoeopathic medicines ­ a Prospective Observational Study with 2-Years Follow-Up

Background Simple and mucopurulent chronic bronchitis (SMCB) is characterized by recurrent mucoid or mucopurulent expectoration in absence of localized suppurative disease. This observational open label study was undertaken to evaluate the effects of homeopathic medicine in SMCB. Methods 1902 patients were screened from 07 centres out of which 1305 were excluded. 597 patients were enrolled as per the inclusion and exclusion criteria. A total of 14 pre-defined homeopathic medicines were shortlisted for prescription after repertorizing the pathological symptoms of SMCB. Outcomes were assessed through chronic bronchitis symptom scale (CBSS) and FEV1/ FVC ratio with spirometry for over a period of two years. Appearance of any change (relief/ worse)/ status quo was immediately followed by placebo/ change in dilution/ change in remedy. Statistical analysis was done using SPSS version 20. Results: 532 patients were analyzed based on the intention to treat principle using last observation carry forward method. Mean CBS score reduced from 29.86±4.5 at baseline to 12.33±7.6 at completion of 2 years. Repeated measures ANOVA, at time points 0 (baseline), 3, 6, 9, 12 ,15, 18, 21 and 24 months, showed significant reduction in CBS scores [Wilk's Lambda 0.104, F=564, df 524; p=00001]. The FEV1 and FEV1/FVC was maintained within normal limits. 86% prescriptions included Lycopodium, Arsenicum album, Pulsatilla, Phosphorus, Stannum metallicum, Calcarea carbonica, Silicea, Bryonia alba. Conclusion: The result suggests effectiveness of homeopathic treatment in early years of SCMB patients. Controlled trials are warranted. (AU)

Antibacterial Activity of Homeopathic Medications Lycopodium clavatum and Arsenicum album Against Periodontal Bacteria / Evaluación antibacteriana de los medicamentos homeopáticos sobre bacterias periodontales

Abstract There are several controversies regarding the efficacy of homeopathic substances; however, these remedies are used in many countries for the treatment of various pathological conditions. The purpose of this study was to evaluate the in vitro antibacterial activity of two homeopathic tinctures Arsenicum album (mineral extract) and Lycopodium clavatum (plant extract) on the periodontal bacteria Actinomyces israelii, Streptococcus sanguinis, Prevotella intermedia, Aggregatibacter actinomycetemcomitans and Phorphyromonas gingivalis (P. gingivalis). Materials and methods: Equal numbers of bacteria were seeded on agar plates containing enriched media with the homeopathic solutions at 1dH and 1cH dilutions. After 7 days of incubation under anaerobic conditions, colony forming units (CFUs) were counted. The antibacterial effect was calculated based on the total number of CFUs observed on non-tincture containing agar, and on the tincture containing plates. Results: No visible growth of any of the strains was observed on the plates containing Arsenicum album at any of the dilutions tested. In contrast, when Lycopodium clavatum at 1cH dilution was tested, only P. gingivalis was susceptible to this compound. Conclusions: The results suggest that the mineral extract tincture had a greater antibacterial activity than the plant extract tincture, also Lycopodium clavatum preparation could be an effective inhibitor of periodontal pathogens bacteria such as P. gingivalis.

Resumen Se necesita un mayor número de estudios in vitro e in vivo para validar estos resultados.

Randomized, double-blind trial on the efficacy of homeopathic treatment in children with recurrent tonsillitis

OBJECTIVE: The efficacy and safety of homeopathic treatment was investigated onchildren with recurrent tonsillitis justifying surgery. METHODS: Prospective, randomized, double-blind clinical trial that included 40 children between ages of 3 to 7 years old;20 children were treated with homeopathic medication and 20 children with placebo. Follow up was 4 months per child. Assessment of results was clinical by means of astandard questionnaire and clinical examination on the first and last day of treatment. Recurrent tonsillitis was defined as 5 to 7 episodes of bacterial acute tonsillitis per year. RESULTS: From the group of 18 children who completed homeopathic treatment, 14 did not present any episode of acute bacterial tonsillitis; from the group of 15 children who received placebo 5 patients did not present tonsillitis; this difference was statistically significant (p= 0,015). None of the patient exhibited side effects. CONCLUSIONS: Homeopathic treatment was effective in children with recurrent tonsillitis compared toplacebo, 14 children (78%) were no longer indicated surgery. Homeopathic treatment was not associated with adverse events.

La vida de lycopodium clavatum / Lycopodium Life Clavatum

Lycopodium clavatum es uno de los medicamentos homeopáticos que se utilizan con mayor frecuencia en la práctica médica, debido a que tiene un campo de aplicación considerable. Por tal motivo, y al igual que como sucede con los demás policrestos, el médico en práctica y el estudiante deben conocer bien sus características (sin que por ello su estudio les lleve a descuidar los demás remedios de la Materia médica). El presente artículo, basado en el método de enseñanza Materia médica vivencial, ofrece un recorrido por la biopatología, la personalidad y las enfermedades que distinguen a Lycopodium clavatum en cada etapa de la vida, además de que brinda aportaciones para la repertorización del paciente. La estructura con que se presenta facilita la comprensión de la patogenesia, por lo que puede permitir una rápida memorización o aclaración de ciertas dudas comunes.

Clavatum Lycopodium is one of homeopathic drugs used most frequently in clinical practice because it has a large field of application. For this reason , and like as with other polychrests , medical practice and the student should be familiar with its features ( without this study leads them to neglect other remedies Materia Medica ) . This article, based on the teaching method experiential Materia Medica , offers a tour of the pathobiology , personality and disease that distinguish Lycopodium clavatum at every stage of life , in addition to providing input to the Repertory patient . The structure is presented that facilitates understanding of the pathogenesis , which can allow rapid memorization or clarification of certain common questions.

Redução e/ou negativação dos anticorpos antitireoidianos com tratamento homeopático: série de casos / Reduced and/or negative anti-thyroid antibodies after homeopathic treatment: a case series

O presente artigo descreve uma série de 9 casos de pacientes, de sexo feminino, idade de 31 a 56 anos, com diagnóstico de tireoidite autoimune, cujos títulos de anticorpos antitireoidianos diminuíram ou negativaram depois de ratamento homeopático. Além disso, em alguns casos foi possível recuperar o equilíbrio funcional da glândula. O acompanhamento foi variável, de 30 dias até 18 anos.

The present article describes a series of 9 cases corresponding to female patients, age 31 to 56 old, diagnosed with autoimmune thyroiditis, who exhibited reduced or negative anti-thyroid antibodies after homeopathic treatment. In some cases, normal function of thyroid was additionally achieved. Follow-up was variable, from 30 days to 18 years.

Personalidad sobreadaptada y homeopatía / Personality sobreadaptada and homeopathy

El presente trabajo está destinado a describir una estructura de personalidad que se observa cada vez con mayor frecuencia, muy favorecida por la actual “cultura del éxito”. Quienes la presentan son personas que sostienen un excesivo ajustea la realidad exterior y a sus exigencias, disociando necesidades y posibilidades emocionales y corporales. Se establece la relación del cuadro psicopatológico con algunos remedios homeopáticos.

This paper is intended to describe a personality structure that is observed with increasing frequency, favored by the current "culture of success". Those who have are people who argue overshootingto external reality and demands decoupling emotional and physical needs and possibilities. The relationship of psychopathology with some homeopathic remedies set.

Diabetes y clínica homeopática / Diabetes and homeopathic clinic

Dentro de la terapéutica médica homeopática ortodoxa lo más importante es la individualidad del paciente, la totalidad de sus síntomas y la elección medicamentosa con base en ello. La diabetes mellitus es calificada por la medicina convencional como una patología de tipo irreversible; sin embargo, siguiendo los principios homeopáticos, para un tratamiento exitoso se debe de tomar en cuenta al enfermo o paciente, y no a la enfermedad o al padecimiento. Asimismo, desde el punto de vista homeopático se buscará el equilibrio integral de los pacientes al presentar un enfoque más amplio, así como una mirada centrada en el individuo enfermo en su conjunto sin perder la importancia del diagnóstico nosológico. Diversos autores han publicado terapéuticas con indicaciones características de algunos medicamentos homeopáticos para cuadros clínicos específicos; en este artículo se realiza una revisión de los más importantes, como Henry Clay Allen, León Vannier, James Tyler Kent, John Henry Clarke y Bernardo Vijnovsky, entre otros, con el fin de proporcionarle ai lector una gama de posibilidades que van de los síntomas orgánicos hasta los mentales, semejantes a los c1asificados dentro del diagnóstico de la diabetes mellitus.

For the orthodox homeopathic medical therapeutics the most important feature is the patient's individuality, aIl symptoms and the drug choice on this basis. Diabetes mellitus is skilled in traditional medicine as an irreversible type pathology, however, following homeopathic principles, in order to get a successful treatment we must to take into account the sick or patient and not the disease or condition. Also from the homeopathic scope, fuIl balance will be sought for patients to present a more comprehensive and focused look at the individual patient as a whole without losing the importance of nosological diagnosis. Several authors have reported therapeutic with indications characteristics of some homeopathic medicines for specific clinical conditions; this article carried out a review of the most important such as Henry Clay Allen, Leon Vannier, James Taylor Kent, John Henry Clarke and Bernardo Vijnovsky, among others, with the order to provide the reader with a range of possibilities based from organic to mental symptoms similar to those ranked in the diagnosis of diabetes mellitus.

Asma bronquial: el abordaje clínica y su repertorización / Bronchial asthma: clinical approach and repertorization

El tratamiento del asma con Homeopatía exige el conocimiento y la destreza del médico para elegir medicamentos adecuados en dos momentos distintos: durante las crisis, en las que se debe actuar con prontitud para permitir la adecuada respiración del paciente, y para corregir la constitución de fondo del caso, a fin de regular la alteración de la respuesta inmunológica y evitar que las fases agudas vuelvan a presentarse.

Asthma management with homeopathy requires the knowledge and skill of the physician to select appropriate drugs at two different moments: during the crisis, in which the physician must act quickly to allow adequate breathing of the patient, and in a second time to correct the constitution of the patient, in order to regulate the alteration of the immune response and prevent that acute phases will appear again.

La personalidad del remedio (Sulphur, Lycopodium, Calcarea carbonica) / Homeopathy diagnosis, personality, Sulphur, Calcarea carb, Lycopodium

Desde la perspectiva de la medicina homeopática, el diagnóstico del paciente no sebasa en la simple observación de un síntoma o rasgo, sino que se requiere de la inteligente integración de todos los componentes posibles del individuo para comprender su complejidad y la de su enfermedad: edad, género, constitución física, gustos alimenticios, conducta, capacidade cognitivas, problemas emocionales, relaciones afectivas, historia familiar y de enfermedades, suprsión de sintomas físicos y actividades que desarrolla. La razón de esto es porque sólo así será posible la correcta prescripción de acuerdo con la Ley de semejanza.

From the homeopathic medicine perspective, the patient's diagnosis is not only based on the simple observation of a symptom or trait, but it requires the intelligent integration of all possible components of the individual, in order to undestand his complexity and his disease: his age, gender, body type, dietary needs, behavioral, cognitive, emotional relationships, and the family history of disease, as the suppression of external physical symptoms and its activities are important thinks to know. The reason for this is because only in this way the homeopath can elaborate the correct prescription in accordance with the Law similarity.

Tratamento homeopático em onicomicose: relato de caso / Homeopathic treatment of onychomychosis: case report

O tratamento homeopático da onicomicose geralmente é muito difícil e os resultados são desanimadores. Do outro lado, o tratamento convencional parece ser mais efetivo, porém, é excessivamente longo e potencialmente tóxico. O presente artigo relata o caso de uma paciente de 28 anos de idade com onicomicose recorrente e cultura positiva para Trycophyton rubrum. Inicialmente foi prescrito um medicamento individualizado, seguido pela associação de um nosódio (Trycophyton). Observou-se melhora do estado geral e da onicomicose, o que sugere que o uso de nosódios com critério isopático pode ser potencialmente efetivo.

Homeopathic treatment of onychomycosis is usually very difficult and outcomes are not favorable. On the other hand, conventional treatment seems more effective, but it is exceedingly long and potentially toxic. This article reports the case of a 28 year-old patient presenting recidivating onychomycosis with positive culture for Trycophyton rubrum. Initially an individualized remedy was selected, followed by the association of a nosode (Trycophyton). The patient improved both in general state and local affection, suggestion that the use of nosodes under isopathic criteria can be potentially effective in the treatment of onychomycosis.

La medicina homeopática ante la epidemia de influenza tipo A H1N1 en México / Homeopathic medicine to the epidemic of influenza A H1N1 in Mexico

La epidemia de influenza aparecida en el mes de abril, documentada ya como una epidemia diferente a la de tipo estacional, se ha manifestado con uma especial virulencia, obligando alas autoridades de la secretaria de Salud a adoptar medidas inusuales en nuestro pais.

Tumor parauterino tratado con lycopodium / Parauterine tumor treated with lycopodium

En el presente artículo se expone la rápida evolución de un tumor parauterino, en una paciente de 36 años de edad a quien como un hallazgo del examen físico, se evidenció la presencia de una tumoración parauterina derecha. En vista de que la paciente se encontraba bajo tratamiento homeopático en pleno proceso curativo, se continúo con la misma medicación indicada durante el mes anterior al hallazgo, en el método plus, con lo cual se logró la resolución de dicha entidad clínica a través de un proceso de exoneración par la vía vaginal

Lycopodium: un niño peculiar / Lycopodium: a peculiar child

El siguiente trabajo, relata a modo de cuento y utilizando los síntomas homeopáticos los rasgos característicos de LYCOPODIUM niño, y también se mencionan otros remedios con los que comparte síntomas o se diferencia de ellos

Congruencia entre materia medica y clinica homeopatica / Congruency between materia medica and homeopathic clinic

Se realizo un estudo retrospectivo de las historias clinicas homeopaticas desde 1995-1998.

Los sueños de lycopodium / The dreams of lycopodium

El autor relaciona lo sueños como expresión de la vida onírica en su contenido manifiesto, con la dinámica mórbida del medicamento en cuestión. Relaciona los de origen patogenético, con la totalidad de los hallados en los repertorios