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Antioxidant effect of two flavonoids from the bark of Ficus bengalensis Linn in hyperlipidemic rats.
Indian J Exp Biol
;
1998 Sep; 36(9): 902-6
Article
in English
| IMSEAR
| ID: sea-60020
ABSTRACT
Two flavonoid compounds, viz. 5,7-dimethyl ether of leucopelargonidin 3-0-alpha-L rhamnoside and 5,3'-dimethyl ether of leucocyanidin 3-0-alpha-D galactosyl cellobioside obtained from the bark of F. bengalensis were evaluated for their antioxidant action in hyperlipidemic rats. The results were compared with the activity of a structurally similar flavonoid, quercetin, a known antioxidant. The Ficus compounds showed significant antioxidant effects which may be attributed to their polyphenolic nature. The methylation of two hydrozyl groups in the Ficus flavonoids might have slowed down their antioxidant action as compared to quercetin.