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Pakistan Journal of Pharmaceutical Sciences. 2005; 18 (2): 14-18
in English | IMEMR | ID: emr-74127

ABSTRACT

Osmotic fragility of red cells is increased by the use of mefenamic acid. The use of this analgesic induces hemolytic anemia. Study of osmotic f agility of RBCs of control and test was observed following administration of 7.1 mg, 10.5 mg and 14 mg/day mefenamic acid to each lizard. Increased osmotic fragility was observed with increase in the amount of dose on day 6 and day 12


Subject(s)
Animals , Erythrocyte Membrane/physiology , Erythrocytes/metabolism , Mefenamic Acid/adverse effects , Mefenamic Acid/metabolism , Hemolysis/drug effects , Mefenamic Acid/metabolism , Mefenamic Acid/pharmacology
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