ABSTRACT
Cryptococcosis is an invasive mycotic infection caused by Cryptococcus neoformans, an encapsulated, yeast-like fungus. It is considered an opportunist infection, since it mainly affects immunocompromised subjects. However there are isolated reports of the infection in immunocompetent subjects. Cryptococcal infection of intra-abdominal organs or tissues is extremely rare. We report a 21-year-old HIV positive male that, during the treatment of a meningeal cryptococcosis, presented a clinical picture of an acute abdomen suggesting acute appendicitis. The patient was operated, finding enlarged mesenteric lymph nodes forming conglomerates and a macroscopically normal appendix. The conglomerated lymph nodes and the appendix were excised. The pathological study of the surgical piece revealed an intra abdominal cryptococcal lymphadenitis and a normal appendix.
Subject(s)
Humans , Male , Young Adult , AIDS-Related Opportunistic Infections/pathology , Abdomen, Acute/microbiology , Appendicitis/pathology , Cryptococcosis/pathology , Mesenteric Lymphadenitis/pathology , Appendicitis/microbiologyABSTRACT
Con el objeto de determinar las alteraciones del sistema fagocitario fijo (SFF) en la fiebre tifoidea, se examinaron retrospectivamente las autopsias de 17 pacientes fallecidos por esta enfermedad durante los años de 1972 a 1982. Las lesiones más constantes fueron: histicitosis con hemofagocitosis en todos los órganos del SFF, microgranulomas en hígado, y bazo, y úlceras intestinales por necrosis de las placas de Peyer. Un hllazgo frecuente en esta revisión, insuficientemente informado en la literatura, es la necrosis con patrón "geográfico" que ocurre en los ganglios linfáticos mesentéricos y en la pulpa roja el bazo