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São Paulo; s.n; 2004. [134] p. ilus, tab, graf.
Thesis in Portuguese | LILACS | ID: lil-397872

ABSTRACT

Avaliação dos efeitos da terapia estro-progestacional isolada ou associada à metiltestosterona, na sexualidade e nos sintomas climatéricos, em mulheres saudáveis na pós-menopausa. Realizou-se estudo de coorte progressiva, duplo-cego, randomizado, com duração de 12 meses, utilizando estrogênios conjugados 0,625 mg e acetato de medroxiprogesterona 2,5 mg associados a metiltestosterona 2 mg (n=31) ou a placebo (n=29). Ambos os tratamentos aumentaram o desejo sexual vinculado, exclusivamente, às atividades desenvolvidas com o parceiro, a excitação, a capacidade orgástica e a freqüência sexual e reduziram a secura vaginal, a dispareunia e os sintomas climatéricos. A associação da metiltestosterona resultou em maior interesse sexual não vinculado, exclusivamente, às atividades com o parceiro e em aumento dos índices de Castelli I e II. /An analysis was conducted of the effects of estrogen-progesterone therapy, prescribed singly or associated with methyltestosterone, on sexuality and climacteric symptoms in healthy postmenopausal women. A progressive, double-blind, randomized cohort series over a 12 month period was realized, employing conjugated estrogens 0,625mg and medroxyprogesterone acetate 2,5mg together with methyltestosterone 2mg (n=31) or placebo (n=29). Both treatments increased sexual desire – linked exclusively to activities developed with the partner – excitation, orgasmic capacity and sexual frequency and they reduced vaginal dryness, dyspareunia and climacteric symptoms. Association of methyltestosterone resulted in major sexual interest, not linked exclusively to activities with the partner, and an increase in Castelli I and II indexes...


Subject(s)
Humans , Female , Adult , Middle Aged , Estrogen Replacement Therapy , Postmenopause , Sexuality , Randomized Controlled Trials as Topic , Estrogens/therapeutic use , Follow-Up Studies , Methyltestosterone/therapeutic use
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