1.
Indian J Physiol Pharmacol
;
1993 Apr; 37(2): 155-7
Article
in English
| IMSEAR
| ID: sea-108827
ABSTRACT
Blood glucose level was estimated in 18 h fasted albino rabbits following acute feeding of graded doses of mianserin. Mianserin (6.0 mg/kg) produced a gradually increasing hyperglycemic effect which became significant (P < 0.01) at 10 h and onwards. This appears to be due to increased turnover and release of noradrenaline by the drug. The same dose of mianserin also produced glucose intolerance during early hours probably by interfering with gastrin functions.