ABSTRACT
Halo nevi (HN), also known as Sutton's nevi or leukoderma acquisitum centrifugum, are nevomelanocytic nevi surrounded by a rim of depigmentation. A 9-year-old female presented with an asymptomatic solitary flesh-colored 0.75-cm-sized papule surrounded by depigmentation on the right cheek 1 month ago. The excisional biopsy demonstrated molluscum contagiosum and decreased basal layer pigmentation on Fontana-Masson stain. The halo phenomenon is often associated with an acquired nevus cell nevus, but has also been associated with a congenital nevus cell nevus, non-neuroectodermal lesions such as angiomas, seborrheic keratoses, lichen planus, sarcoid, psoriasis, involuting flat warts, and histiocytoma. Our patient had an unusual association of molluscum contagiosum with the halo phenomenon. We suppose that the halo phenomenon in this patient might have been provoked by the molluscum contagiosum virus. A halo nevus-like appearance suggests the possibility of disease other than nevus. In such cases, skin biopsy is required for confirmation.
Subject(s)
Child , Female , Humans , Biopsy , Cheek , Hemangioma , Histiocytoma , Keratosis, Seborrheic , Lichen Planus , Molluscum contagiosum virus , Molluscum Contagiosum , Nevus , Nevus, Halo , Pigmentation , Psoriasis , Skin , WartsABSTRACT
Molluscum contagiosum is a viral infection of the skin and mucous membranes which is caused by a DNA virus from the poxvirus family. It is usually transmitted by direct skin contact, autoinoculation or fomites. Children are generally affected, and adults who are immunocompromised or sexually active may also be afflicted. Although molluscum lesions can be presented on any skin surface of the body, its occurrence on the sole is unusual. Molluscum contagiosum virus appears to have a particular affinity for follicular epithethelium and it may explain its lack of sole involvement. A 30-year-old male had a small pea sized nodule on his right sole that had been present for several days. Histological examination showed numerous molluscum bodies within the epithelium. Herein, we report a rare case of solitary molluscum contagiosum on the right sole of a healthy male patient.
Subject(s)
Adult , Child , Humans , Male , DNA Viruses , Epithelium , Fomites , Molluscum Contagiosum , Molluscum contagiosum virus , Mucous Membrane , Pisum sativum , SkinABSTRACT
No abstract available.
Subject(s)
Epidermal Cyst , Molluscum Contagiosum , Molluscum contagiosum virusABSTRACT
El molusco contagioso es una infección viral de la piel y ocasionalmente de las mucosas. El agente etiológico es un poxvirus ADN tipo 1 y 2. Comúnmente se presenta como pápulas perladas y pequeñas, que miden de 1 a 5 mm de diámetro y poseen una umbilicación central. Las lesiones atípicas que involucran los folículos pilosos y las lesiones solitarias pueden requerir del estudio histopatológico para confirmar el diagnóstico. Presentamos el caso de una paciente portadora de un molusco contagioso atípico por su gran dimensión.
Molluscum contagiosum is a viral infection of the skin and, occasionally, of the mucous membranes. The causative agent is the DNA poxvirus types 1 and 2. It commonly presents with pearly, small, 1 to 5 mm papules, with central dimpling. Atypical lesions involving the hair follicles and solitary lesions may require histological study to confirm the diagnosis. We present a patient with an atypical giant molluscum contagiosum.
Subject(s)
Humans , Female , Infant , Molluscum Contagiosum , Molluscum contagiosum virusABSTRACT
Molluscum contagiosum is a common cutaneous disease that may be difficult to treat when there are multiple lesions; especially in children. This study was conducted to determine the efficacy of pulsed dye laser (585 nm) in the treatment of molluscum contagiosum in 20 children. In the treated group, 70.5% of lesions healed after the first treatment; the remaining 10.6% after the second treatment (2 weeks later). The overall cure rate was significantly different from the control group (p< 0.01). The therapy was also well tolerated. Only mild transient hypopigmentation and erythema were observed. None encountered infectious events. In conclusion, pulsed dye laser is a good alternative treatment for molluscum contagiosum due to high efficacy and mild transient side effects.
Subject(s)
Adolescent , Child , Child, Preschool , Female , Humans , Infant , Lasers, Dye/adverse effects , Male , Molluscum Contagiosum/therapy , Molluscum contagiosum virus/classificationSubject(s)
Abscess/complications , Acquired Immunodeficiency Syndrome/complications , Anti-Bacterial Agents , Bacteria/isolation & purification , Child, Preschool , Drug Therapy, Combination/therapeutic use , Eye Infections, Viral/complications , Eyelid Diseases/complications , Eyelids/microbiology , Follow-Up Studies , Fungi/isolation & purification , HIV Antibodies/analysis , HIV-1/immunology , Humans , Male , Molluscum Contagiosum/complications , Molluscum contagiosum virus/isolation & purificationABSTRACT
BACKGROUND: Recent restriction enclonuclease analysis studies hsve revealed that MCV DNA can be classified into two major types, designated MCV-1 and MCV-2, by th:ir restriction enzyme cleavsge patterns. In earlier reports of MCV DNA analysis, MCV-2 was the main virus type found in genital lesions. However many recent studies cienied the relationship between virus type and anatomical distribution. OBJECTIVE: The purpose of this study was to examine the ratio of MCV-l to MCV-2 in Korean isolates of MCV DNA and the relationship between MCV subtypes and with clinical features such as anatomical location, age, sex, numiber of lesions, and atopic dermatitis. METHODS: MCV DNA extrated from 112 cases of Korean patients waa examined by restriction endonuclease analysis using Brtm HI. RESULTS: 1. MCV-1 was found in 108 of 112 (96.4%) patients and MCV-2 in of 112 (3.6%) patients. The ratio of MCV-1 to MCV-2 wss 28:1. 2. There was no significant ciprrelation between MCV subtypes and the age, sex, number of lesions, atopic dermatitis, and anatoimic loction. 3. Lesions induced by MCV-1 MCV-2 were indistinguishable on the brsis of size and form. CONCLUSION: This study showis that the ratio of MCV-1 to MCV-2 was 28:1 in Korean molluscum contagiosum patients and there was no relationship between MCV subtyies and lesional morphology or snatomical distribution.
Subject(s)
Humans , Dermatitis, Atopic , DNA , DNA Restriction Enzymes , Molecular Epidemiology , Molluscum contagiosum virus , Molluscum ContagiosumABSTRACT
Within a 2-year period 100 patients with molluscum contagiosum [M.C.] were studied for the presence of hyphae-like structures in their white core which is expressed from the center of the lesions. We prepared the white core of M.C. papules buffered with 20% KOH for direct microscopic examination, and found hyphae-like structures in 55% of patients. Culture of white core for fungi and yeasts, and P.A.S. staining of tissues obtained by biopsy of skin lesions were negative in 27 and eight patients, respectively
Subject(s)
Molluscum Contagiosum/complications , Skin Diseases/etiology , Biopsy , Molluscum contagiosum virus/pathogenicityABSTRACT
Vinte e um casos de molusco contagioso foram escolhidos para serem analisados por testes sorológicos e de microscopia eletrônica. O vírus do molusco foi detectado nas crostas e observados também nos vacúolos formados dentro dos queratinócitos. Os pacientes desenvolveram anticorpos fixadores do complemento para o vírus