ABSTRACT
Primary follicular mucinosis is a rare dermatosis characterized by the accumulation of mucin in the follicular epithelium and sebaceous glands. Clinically, it is characterized by the presence of papules or well-circumscribed and infiltrated plaques. In this paper, we report the case of a female patient, seven years old, evolving for three months with an asymptomatic, erythematous and infiltrated plaque located in the chin region. The research of thermal, pain and tactile sensitivity was inconclusive. Histological findings confirmed the diagnosis of follicular mucinosis. There was regression of the lesion with the use of medium potency topical corticosteroids for 20 days. The pathogenesis of follicular mucinosis remains unknown, being in some cases associated with lymphoproliferative disorders. In endemic areas of leprosy, isolated and infiltrated follicular mucinosis lesions should be further differentiated from leprosy.
.Subject(s)
Child , Female , Humans , Facial Dermatoses/pathology , Leprosy, Tuberculoid/pathology , Mucinosis, Follicular/pathology , Diagnosis, Differential , Endemic DiseasesABSTRACT
Follicular mucinosis, also known as alopecia mucinosa, is a cutaneous mucinosis histologically characterized by accumulation of dermal type mucin in the pilosebaceous follicle and sebaceous glands. It presents in two forms, a primary or idiopathic form and a secondary form associated with various benign or malignant processes. Among the malignant processes, the main association is with mycosis fungoides. The frequent overlap of clinical, histopathological, immunohistochemical and molecular biology characteristics makes the correct classification of these conditions difficult, therefore a long follow-up of all cases is recommended. We report the case of an adolescent with disseminated lesions and discuss the difficulty of early identification of secondary follicular mucinosis associated with cutaneous lymphoma.
Subject(s)
Humans , Male , Adolescent , Skin Neoplasms/pathology , Mycosis Fungoides/pathology , Mucinosis, Follicular/pathology , Mucins/analysisSubject(s)
Humans , Male , Adolescent , Mucinosis, Follicular/diagnosis , Mucinosis, Follicular/pathologyABSTRACT
Presentamos el caso de un varón de 55 años que desarrolló placas eritematosas con alopecia en cabeza, tronco y extremidades. Cuatro biopsias de piel mostraron degeneración micinosa de la vaina radicular externa del folículo piloso avalando el diagnóstico de mucinosis folicular. Diez meses después el paciente se presentó con extensas placas induradas y nódulos. El examen microscópico de numerosas muestras obtenidas de la espalda y las extremidades revelaron los cambios microscópicos de la micosis fungoide. El caso presentado confirma la necesidad de tomar numerosas muestras en la evaluación de los pacientes con mucinosis folicular diseminada y destaca la dificultad en el diagnóstico diferencial, clínico e histológico, con la micosis fungoide
Subject(s)
Humans , Male , Middle Aged , Mucinosis, Follicular/pathology , Mycosis Fungoides/complications , Diagnosis, Differential , Mucinosis, Follicular/diagnosis , Mycosis Fungoides/pathologyABSTRACT
Alopecia mucinosa es una enfermedad inflamatoria caracterizada por el depósito de mucopolizacáridos ácidos en la unidad pilosebácea con alopecia reversible. Puede representar una forma idiopática benigna o un marcador cutáneo de malignidad subyacente, según los casos. Se presenta un caso clínico
Subject(s)
Adult , Humans , Female , Dapsone/therapeutic use , Glycosaminoglycans , Mucinosis, Follicular/diagnosis , Mucinosis, Follicular/pathology , Sebaceous Gland DiseasesABSTRACT
A alopécia mucinosa é uma desordem inflamatória caracterizada clinicamente por pápulas foliculares agrupadas e alopécia. A análise histopatológica demonstra degeneraçäo mucinosa da unidade pilosebásea. A alopécia mucinosa é geralmente, uma dermatose benigna e autolimitada, especialmente quando acomete crianças ou adultos jovens, e quando é constituída de poucas lesöes, restritas à extremidade cefálica. No entanto, um pequeno número de casos se associa com reticuloses. Os autores descrevem um caso de alopécia mucinosa universal associada à micose fungóide