ABSTRACT
Abstract: Background: Vitiligo is an acquired pigmentary skin disorder affecting 0.1-4% of the general population. The nails may be affected in patients with an autoimmune disease such as psoriasis, and in those with alopecia areata. It has been suggested that nail abnormalities should be apparent in vitiligo patients. Objective: We sought to document the frequency and clinical presentation of nail abnormalities in vitiligo patients compared to healthy volunteers. We also examined the correlations between nail abnormalities and various clinical parameters. Methods: This study included 100 vitiligo patients and 100 healthy subjects. Full medical histories were collected from the subjects, who underwent thorough general and nail examinations. All nail changes were noted. In the event of clinical suspicion of a fungal infection, additional mycological investigations were performed. Results: Nail abnormalities were more prevalent in the patients (78%) than in the controls (55%) (p=0.001). Longitudinal ridging was the most common finding (42%), followed by (in descending order): leukonychia, an absent lunula, onycholysis, nail bed pallor, onychomycosis, splinter hemorrhage and nail plate thinning. The frequency of longitudinal ridging was significantly higher in patients than in controls (p<0.001). Conclusions: Nail abnormalities were more prevalent in vitiligo patients than in controls. Systematic examination of the nails in such patients is useful because nail abnormalities are frequent. However, the causes of such abnormalities require further study. Longitudinal ridging and leukonychia were the most common abnormalities observed in this study.
Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Young Adult , Vitiligo/epidemiology , Nails, Malformed/epidemiology , Turkey/epidemiology , Vitiligo/complications , Vitiligo/pathology , Case-Control Studies , Prevalence , Hypopigmentation/epidemiology , Statistics, Nonparametric , Nail Diseases/congenital , Nail Diseases/epidemiology , Nails, Malformed/etiology , Nails, Malformed/pathologyABSTRACT
A rare case of 29 years old healthy male patient with persistent progressive total whitening of all the finger and toe nails [Idiopathic acquired leukonychia] since the age of 20 years is being presented here. The nail changes were of great concern in terms of social embarrassment to the patient. Idiopathic acquiredleukonychia is a rare chromatic disorder of the nails not associated with other abnormalities and discernible etiology. To the best of our knowledge, probably it is the second case report from India after the first one reported from Mumbai earlier. Hence it is presented here for its rarity
Subject(s)
Humans , Male , Nail Diseases/congenital , Nail Diseases/diagnosis , Hypopigmentation/etiologyABSTRACT
Las alteraciones ungueales en los niños representan un número de consultas no despreciable tanto en atención primaria y pediatría como en dermatología. Algunas alteraciones son idénticas a las de los adultos, pero existen otras que son características de esta etapa de la vida y que nos pueden ayudar en el diagnóstico. En este resumen describimos las principales alteraciones ungueales en la infancia
Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Nail Diseases/diagnosis , Ectodermal Dysplasia/diagnosis , Dyskeratosis Congenita/diagnosis , Nail Diseases/congenital , Progeria/diagnosis , Skin Diseases, Infectious/diagnosis , Skin Diseases/complications , Nails/embryologyABSTRACT
A case of pachyonchia congenital treated by removal of nail plates and excision of the ventral nail beds is described