ABSTRACT
One hundred new born males babies aged 7 days and above were included in this study. These were divided into two groups - Group I included G6PD normal subjects and Group II included G6PD deficient subjects. Total bilirubin and G6PD enzyme levels were done by commercially available kits. Results were analysed by using students t test and level of significance was done. A significant increase in total bilirubin level was observed in infants of G6PD deficiency, Erythrocyte G6PD level is significantly decreased in 06% of infants born with neonatal jaundice
Subject(s)
Humans , Male , Glucosephosphate Dehydrogenase Deficiency , Bilirubin/blood , Erythrocytes/enzymology , Anemia, Hemolytic/etiology , Antimalarials/adverse effects , Sulfonamides/adverse effects , Aspirin/adverse effects , Nalidixic Acid/adverse effects , Anthelmintics/adverse effects , Probenecid/adverse effectsSubject(s)
Adolescent , Adult , Age Factors , Animals , Anti-Infective Agents/adverse effects , Bone Development/drug effects , Cartilage/drug effects , Child , Child, Preschool , Ciprofloxacin/adverse effects , Female , Fluorides/adverse effects , Growth/drug effects , Humans , Infant , Infant, Newborn , Male , Nalidixic Acid/adverse effectsSubject(s)
Humans , Tetracyclines/adverse effects , Triazolam/adverse effects , Benzodiazepines/pharmacokinetics , Nomifensine/adverse effects , Phenacetin/adverse effects , Cimetidine/pharmacokinetics , Amiodarone/adverse effects , Hydrochlorothiazide/adverse effects , Nalidixic Acid/adverse effects , Ferrous Compounds/pharmacokinetics , Amiloride/adverse effects , Hydrochlorothiazide/adverse effectsABSTRACT
Se presenta la observación de seis lactantes en quienes se comprobó síntomas de hipertensión endocraneana con abombamiento de la fontanela anterior, durante el tratamiento con ácido nalidíxico. Se pudo realizar la contraprueba en tres de los niños, demostrando la repetición de los síntomas en dos de ellos.