ABSTRACT
La región vulvovaginal es una zona muy compleja por todos los elementos que la conforma y puede ser origen de un gran número de tumores benignos y en menor frecuencia de tumores malignos. En las últimas décadas, los tumores vulvovaginales han tenido un avance significativo en cuanto a su diagnóstico y tratamiento, dado por las aportaciones de la biología celular y molecular. El presente artículo pretende ser una referencia práctica para el diagnóstico clínico e histopatológico de estos tumores benignos así como en el tratamiento ambulatorio de algunos de ellos y su vigilancia.
The vulvovaginal region is a very complex area because of its anatomy and the fact that it can be source of a large number of benign tumors and less frequent malignant tumors. In recent decades, there have been significant gains in the diagnosis and treatment of vulvovaginal tumors, thanks to the contributions of cellular and molecular biology. The purpose of this review article is to serve as a practical reference for clinical and pathological diagnosis as well as in the outpatient treatment and monitoring of these benign tumors.
Subject(s)
Female , Neoplasms, Fibroepithelial/surgery , Neoplasms, Fibroepithelial/diagnosis , Vulvar Neoplasms/surgery , Vulvar Neoplasms/diagnosis , Diagnosis, Differential , Neoplasms, Fibroepithelial/pathology , Vulvar Neoplasms/pathology , Polyps/surgery , Polyps/diagnosisABSTRACT
No abstract available.
Subject(s)
Female , Humans , Middle Aged , Diagnosis, Differential , Endosonography , Incidental Findings , Intestinal Mucosa/pathology , Intestinal Polyps/diagnosis , Neoplasms, Fibroepithelial/diagnosis , Predictive Value of Tests , Rectal Neoplasms/diagnosis , Tomography, X-Ray ComputedABSTRACT
Fibroepithelial tumors of the breast including fibroadenomas and phylloides tumors arise from epithelial and stromal components of the terminal duct-lobular unit. Fibroadenoma is the commonest benign neoplasm of the female breast. These tumors are found as early as puberty. Mammary phylloides tumors are uncommon stromal-epithelial neoplasms and are divided into benign, borderline malignant and frankly malignant groups on the basis of their histological features. The aim of this study is to evaluate the role of morphologic diagnosis in a series of fibroepithelial [biphasic] tumors of the breast including fibroadenoma and phylloides tumor, highlighting the morphological and Histopathological variants of fibroadenoma, and the most recent histological classification criteria of phylloides tumors. This is a retrospective study including 250 cases of fibroepithelial tumors of the female breast, from October 2007 to September 2008. Cases were taken from private laboratories. All cases were excisional biopsy, the specimens were already fixed in 10% formalin and paraffin embedded.Sections of 4 microns were made from the paraffin blocks and stained with hematoxyllin and eosin stain and examined microscopically. Two-hundred and fifty cases of mammary fibroepithelial tumors were reviewed in this study. The age of the patients ranged between 14-49 years, and the tumor size ranged between 1.5-20 cm. The cases were histologically classified into: 220[88%] cases of fibroadenoma[FA] and 30[12%] cases of phylloides tumor[PT]. Additional morphological features of fibroadenoma were: fifteen[6.8%]cases juvenile fibroadenoma, infarction in eight[3.6%] cases, lactational changes in ten[4.5%] cases, multinucleated giant cells in the stroma in six[2.7%] cases, prominent myxoid changes in three[1.4%] cases, features of fibrocystic changes in the surrounding in 14[6.4%] cases, cellular stroma in eight [3.6%] cases, apocrine metaplasia in 26[11.9%] cases, hyalinization and calcification of the stroma in 14[6.4%] cases, presence of adipose tissue, muscle or cartilage in 18[8.2%] cases, atypical epithelial hyperplasia in four[1.8%] cases, and ordinary fibroadenomas [non-otherwise specific] in 94[42.7%] cases. Multiple fibroademnomas were found in 20[9.1%] cases. Histological classification of the phylloides tumors showed 20[66.7%] benign cases, six[20%] cases borderline malignant and four[13.3%] malignant cases. Filroadenoma is the commonest fibroepithelial tumor of female breast, phylloides tumor is an uncommon neoplasm which is usually benign but malignant variant exists
Subject(s)
Humans , Female , Neoplasms, Fibroepithelial/diagnosis , Fibroadenoma , Phyllodes Tumor , Retrospective StudiesABSTRACT
Presentamos el caso de un paciente con tumor fibroepitelial de pinkus localizado en dorso a nivel de la línea media. Realizamos una revisión bibliográfica y un comentario de las implicancias que presenta el commentario de las implicancias que presenta el comportamiento de este tumor de aparición infrecuente
Subject(s)
Humans , Male , Middle Aged , Carcinoma, Basal Cell/diagnosis , Neoplasms, Fibroepithelial/diagnosis , Back/pathologyABSTRACT
El pólipo fibroepitelial es una lesión benigna de piel y mucosa genital y perineal. Se presenta en mujeres jóvenes, es poco frecuente e histológicamente muestra estroma laxo con prominentes y numerosas células atípicas, pleomórficas, multinucleadas. La lesión puede confundirse con rabdomiosarcoma botrioide, angiomixoma agresivo y neurofibroma mixoideo. Se revisaron los casos de nuestro archivo del período 1990-1996. Se recolectaron 13 casos, todas mujeres, cuya edad varió de recién nacido a 74 años. El tamaño de la lesión fluctuó de 0,3 a 2,5 cm; 12 lesiones únicas y 1 múltiple; localizaciones: vagina 6 (46,2 por ciento), ano 3 (23,1 por ciento), vulva 2 (15,4 por ciento) y uretra 1 (7,7 por ciento); en 1 caso la localización no se consignó. Histológicamente, las lesiones presentaban revestimiento escamoso normotípico, estroma, conjuntiva laxo, vascularizado, con moderada cantidad de células atípicas, pleomórficas, en partes formando rosetas, sin mitosis ni invasión del epitelio. Esta veriedad de papiloma es una lesión benigna, que simula sarcoma, que debe tenerse presente en el diagnóstico diferencial de sarcoma y pseudosarcoma de mucosa vaginal y piel perineal