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Indian Pediatr ; 2004 Nov; 41(11): 1129-32
Article in English | IMSEAR | ID: sea-12921

ABSTRACT

Linezolid is an oxazolidinone antibacterial agent that acts by inhibiting the initiation of bacterial protein synthesis. Linezolid has a wide spectrum of activity against gram-positive organisms including methicillin resistant staphylococci, penicillin resistant pneumococci and vancomycin resistant enterococcus faecalis and E. faecium. Linezolid has a good bio-availability orally and could be switched from parenteral to oral therapy while treating serious infections. Linezolid is well tolerated in children.


Subject(s)
Acetamides/adverse effects , Adult , Anti-Bacterial Agents/adverse effects , Child , Gram-Positive Bacterial Infections/drug therapy , Humans , Oxazolidinones/adverse effects , Protein Biosynthesis/drug effects , Protein Synthesis Inhibitors/adverse effects
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