Central Nervous System Paracoccidioidomycosis: an overview

Paracoccidioidomycosis (PCM) is an infectious disease, endemic to subtropical areas of Central and South America, caused by the dimorphic fungus Paracoccidioides brasiliensis. It is a chronic disease, mostly affecting adult males, with a mean patient age of 44 years. Central nervous system involvement (CNS PCM) has been found in 13 percent of the patients with systemic disease. We reviewed the clinical presentation, diagnosis techniques and treatments for CNS PCM.