ABSTRACT
Background Hemangiomas are benign neoplasms of capillary proliferation that arise from a developmental anomaly where angioblastic mesenchyme fails to form canals. Most hemangiomas arise in the head and neck region, either superficially in the skin or deeper within endocrine organs such as the parotid gland. Parathyroid hemangiomas, however, are extremely rare, with only five cases previously reported in the literature. Case presentation Herein, we present a case of a 68-year-old man with a hemangioma almost completely replacing the right upper parathyroid gland, grossly measuring 1.3 × 1.3 × 1.2 cm and weighing 700 mg, associated with primary hyperparathyroidism. Conclusions Parathyroid gland enlargement due to vascular neoplasms such as hemangiomas can mimic, both clinically and radiographically, hyperplasias and/or adenomas. Surgeons need to be aware of the presence of this entity and should consider it in the differential diagnosis of hyperparathyroidism or parathyroid gland enlargement.
Subject(s)
Humans , Male , Aged , Parathyroid Neoplasms/pathology , Adenoma/pathology , Hemangioma/pathology , Parathyroid Diseases/complications , Diagnosis, DifferentialABSTRACT
Parathyroid cysts (PCs) are rare lesions, located in the neck and anterior mediastinal region. The vast majority are non-functioning, presented as nodular cervical lesions. Large, non-functioning PCs can manifest with compressive symptoms of the surrounding tissues. Rarely, PCs produce excessive amounts of parathyroid hormone (PTH), resulting in primary hyperparathyroidism. We report a case of functional PC, describing its diagnostic and therapeutic approach.
Os cistos de paratireoide (PCs) são lesões raras, localizadas no pescoço e na região do mediastino anterior. A grande maioria é não funcionante, apresentando-se como lesões cervicais nodulares. PCs não funcionantes de grandes dimensões podem se manifestar com sintomas compressivos. Raramente, PCs produzem quantidades excessivas de hormônio da paratireoide (PTH), o que resulta em hiperparatiroidismo primário. Relatamos um caso de PC funcional, descrevendo sua abordagem diagnóstica e terapêutica.
Subject(s)
Female , Humans , Middle Aged , Adenoma/pathology , Cysts/pathology , Parathyroid Diseases/pathology , Parathyroid Neoplasms/pathology , Adenoma/surgery , Calcium/blood , Cysts/surgery , Parathyroidectomy , Parathyroid Diseases/complications , Parathyroid Diseases/surgery , Parathyroid Hormone/blood , Parathyroid Neoplasms/complications , Parathyroid Neoplasms/surgeryABSTRACT
Se resentan los datos de 40 pacientes, portadores de insuficiencia renal crónica, atendidos en el Servicio de Nefrología y la Unidad de Hemodiálisis del Hospital San Juan de Dios, San José, Costa Rica, de enero a junio de 1997. De ellos 9 pacientes con insuficienca renal crónica en etapa prediálisis, 7 casos en terapia de hemodiálisis y 24 pacientes postrasplante renal, analizando la incidencia y severidad del daño óseo, la repercusión sobre las paratiroides y el daño renal secundario al hiperparatiroidismo. Palabras claves: Hiperparatiroidismo secundario, osteodistrofia renal, insuficiencia renal crónica, parathormona, trasplante renal
Subject(s)
Humans , Bone Marrow Diseases , Chronic Kidney Disease-Mineral and Bone Disorder , Hyperparathyroidism, Secondary , Parathyroid Diseases/complications , Parathyroid Diseases/etiology , Renal Insufficiency , Kidney Transplantation , Costa RicaABSTRACT
Relatamos o caso de um homem de 25 anos de idade portador de hiperparatiroidismo primário (HPP) sintomático (litíase renal, osteoporose à densitometria óssea, lesöes radiológicas sugestivas de HPP e biópsia óssea revelando tumor gigantocelular). Entretanto, mesmo com todos estes achados, o paciente apresentava-se normocalcêmico e com níveis séricos de PTH intacto de 155 pg/ml (normal 13-54 pg/ml). Foi submetido a cervicotomia exploradora que revelou um nódulo de 2,5 cm de diâmetro posterior ao polo inferior do lobo tiroidiano direito, cujo anátomo-patológico foi compatível com cisto de paratiróide fibrótico, com áreas de necrose. Um mês após a cirurgia, o paciente apresenta-se com hipocalcemia assintomática e persiste com dores ósseas difusas. Discutimos o caso em questäo e revisamos a literatura a respeito do assunto.