Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add filters








Language
Year range
1.
Int. j. morphol ; 32(4): 1222-1227, Dec. 2014. ilus
Article in English | LILACS | ID: lil-734662

ABSTRACT

This investigation was undertaken in order to quantify the effects of early polysensorial enrichment on the development of cortical pyramids, located in the parietal cortex of rats simultaneously submitted to protein-energy undernutrition. A short period of stimulation during suckling significantly decreases the cellular density in the cortical plate (phylogenetic-ontogenetic evolutionary index). Results suggest that the cerebral cortex develops according to a sophisticated neuronal network, which exhibits a notable degree of structural specificity, regulated by genetic and environmental clues. The most obvious prediction is that environmental influences are probably transduced as a structural expression in the developing parietal cortical plate.


La presente investigación se realizó con la finalidad de cuantificar los efectos del enriquecimiento polisensorial temprano sobre el desarrollo de células piramidales de la corteza parietal, en ratas que simultáneamente fueron sometidas a desnutrición calórico-proteica. Un breve periodo de estimulación durante el periodo de lactancia disminuyó significativamente la densidad celular en la placa cortical (índice evolutivo filogenético-ontogenético). Los resultados sugieren que la corteza cerebral se desarrolla de acuerdo con una red neuronal altamente sofisticada, la cual exhibe un notable grado de especificidad estructural regulada por claves genéticas y ambientales. La predicción más obvia es que las influencias ambientales son probablemente traducidas como expresión estructural en la placa cortical parietal.


Subject(s)
Animals , Rats , Parietal Lobe/anatomy & histology , Parietal Lobe/growth & development , Protein-Energy Malnutrition , Environment , Rats, Sprague-Dawley
SELECTION OF CITATIONS
SEARCH DETAIL