Asociación de la salud cardiometabólica de preescolares y sus padres con características nutricionales y sociodemográficas familiares / Association of cardiometabolic health of preschoolers and their parents with family sociodemographic characteristics

Introducción: Existe escaso conocimiento sobre la asociación entre marcadores cardiometabólicos en preescolares con características nutricionales y sociodemográficos familiares. Objetivo: Determinar la asociación entre marcadores cardiometabólicos de preescolares y sus padres con las características nutricionales y sociodemográficas familiares. Materiales y Métodos: Estudio de corte transversal, de asociación y correlación entre variables Padre-Hijo/a de carácter multicéntrico, en el cual participaron 140 sujetos (70 preescolares y su respectivo padre o madre). Las variables fueron estado nutricional, composición corporal, fuerza prensil y presión arterial de padres/madres y sus hijos/as preescolares y variables sociodemográficas de las familias. Resultados: Existió diferencia significativa al 5% respecto de la obesidad de los padres con la de los hijos/as, se presentó correlación positiva (0,397) entre las variables "porcentaje de grasa" padres e hijos/as. En relación al "nivel de escolaridad de la madre" hubo diferencia significativa con el "porcentaje de grasa" de los hijos/as (p<0,011). Existió similarmente diferencia significativa (p=0,033) entre la variable "tener hermanos" respecto a la variable "porcentaje de grasa" de los hijos/as. Finalmente se presentó asociación entre "usa Tablet" (dispositivo audiovisual) y "presión arterial" de los hijos/as (p=0,030). La variable "usa Tablet" se asoció significativamente con la "fuerza prensil" de los hijos/as (p=0,044). Conclusiones: Padres obesos con alto porcentaje de grasa tienen hijos/as preescolares con bajo perfil cardiometabólico; las variables nivel educacional inferior de la madre y tener hermanos se asociaron a un mayor porcentaje de grasa en los hijos/as, conjuntamente el uso de Tablet en preescolares mostró mayores niveles de presión arterial y menor fuerza prensil(AU)

Introduction: Little is known about the association between cardiometabolic markers in preschoolers with family nutritional and socio- demographic characteristics. Objective: To determine the association between cardiometabolic markers in preschoolers and their parents with family nutritional and sociodemographic characteristics. Materials and methods: cross-sectional study of association and correlation between parent-child variables, multicenter, 140 subjects participated (70 preschoolers and their respective parents). The variables were nutritional status, body composition, prehensile strength and blood pressure of parents and their preschool children and sociodemographic variables of the families. Results: There was a significant difference at 5% between parents' obesity and children's obesity, with a positive correlation (0.397) between the variable "percentage of fat" parents/children. In relation to the "mother's level of schooling" there was a significant difference with the "percentage of fat" of the children (p<0.011). Similarly, there was a significant difference (p=0.033) between the variable "Having siblings" with respect to the variable "percentage of fat" of the children. Finally, there was an association between "Tablet use" (audiovisual device) and "blood pressure" of the children (p=0.030). The variable "Tablet use" was significantly associated with the "prehensile strength" of the children (p=0.044). Conclusions: Obese parents with a high percentage of fat have preschool children with a low cardiometabolic profile; the variables lower educational level of the mother and having siblings were associated with a higher percentage of fatness in children; together, the use of Tablet in preschoolers showed higher levels of blood pressure and lower prehensile strength(AU)

Asociación del índice de masa corporal con la insatisfacción corporal en escolares / Association of body mass index with body dissatisfaction in schoolchildren

Introducción: La malnutrición por exceso causa sobrepeso y obesidad, siendo un problema de salud pública, que se ha presentado en los primeros años de vida. Investigaciones realizadas han informado la existencia de insatisfacción corporal relacionada con el peso, debido a los estándares de belleza establecidos en la sociedad. Objetivo: asociar el índice de masa corporal con la insatisfacción corporal y percepción de la imagen corporal de los escolares. Materiales y métodos: estudio transversal con 610 escolares. El estado nutricional se clasificó según el puntaje z del IMC. Para determinar la insatisfacción corporal y la percepción de la imagen corporal, se aplicó una escala de imagen corporal infantil de siete fotografías, con un valor del 1 al 7 de acuerdo con el tamaño creciente, y el rango final del IMC. Se calculó la diferencia entre la figura que los participantes consideraron ideal y la forma corporal percibida. Resultados: el 47,3% presentaron sobrepeso y obesidad. La insatisfacción corporal fue mayor en las niñas con sobrepeso y obesidad (p = 0,013). El IMC correlacionó con la insatisfacción corporal (rho(608) = 0,480; p < 0,001) y la percepción de la imagen corporal (rho(608) = 0,433; p < 0,001). Conclusiones: El IMC se relacionó positivamente con la insatisfacción corporal y la percepción de la imagen corporal; esto podría elevar el riesgo de presentar trastornos alimentarios, contribuir al mantenimiento del exceso de peso corporal, al no percibirse con exceso de peso, es menos probable que realicen acciones para controlarlo(AU)

Introduction: Excessive malnutrition causes overweight and obesity, being a public health problem, which has occurred in the first years of life. Research has reported the existence of body dissatisfaction related to weight, due to beauty standards established in society. Objective: to associate the BMI with body dissatisfaction and body image perception of schoolchildren. Materials and methods: cross-sectional study of 610 schoolchildren. Nutritional status was classified according to the BMI z score. To determine body dissatisfaction and body image perception, a child body image scale of seven photographs was applied, with a value of 1 to 7 according to the increasing size, and the final range of the BMI. The difference between the figure that participants considered ideal, and the perceived body shape was calculated. Results: 47.3% were overweight and obese. Body dissatisfaction was higher in overweight and obese girls (p = 0.013). BMI correlated with body dissatisfaction (rho(608) = 0.480; p < 0.001) and body image perception (rho(608) = 0.433; p < 0.001). Conclusions: BMI was positively related to body dissatisfaction and body image perception; this could increase the risk of developing eating disorders, contribute to the maintenance of excess body weight, as it is not perceived with excess weight, are less likely to take actions to control it(AU)

Impacto de la pandemia por SARS-CoV-2 en el índice de masa corporal de niños asistidos en la Ciudad Autónoma de Buenos Aires / Impact of the SARS-CoV-2 pandemic on the body mass index of children seen in the City of Buenos Aires

Introducción. El sobrepeso y la obesidad infantil constituyen un problema de salud pública. El inicio de la pandemia por COVID-19 pudo haber favorecido esta patología. El puntaje Z del índice de masa corporal (Z-IMC) es un indicador aceptado para su diagnóstico y seguimiento. Objetivo. Evaluar si la prevalencia de sobrepeso y obesidad, y el Z-IMC en niños de 2 a 5 años aumentó durante la pandemia. Población y métodos. Estudio de cohorte retrospectiva. Se incluyeron pacientes asistidos en efectores públicos de salud del Gobierno de la Ciudad Autónoma de Buenos Aires (GCABA), de 2 a 5 años de edad, con registro de peso y talla en dos consultas, antes y después de haber comenzado el aislamiento social preventivo y obligatorio (ASPO). Se registró estado nutricional (Z-IMC) y variación del Z-IMC entre ambas consultas. Resultados. Se evaluaron 3866 sujetos, edad promedio 3,4 ± 0,8 años; el 48,1 % fueron mujeres. El intervalo promedio entre consultas fue 14,3 ± 2,5 meses. La prevalencia de sobrepeso/obesidad aumentó del 12,6 % (IC95% 11,6-13,6) al 20,9 % (IC95% 19,6-22-2); p <0,001, al igual que el Z-IMC (0,4 ± 1,1 vs. 0,8 ± 1,3; p <0,001). Conclusión. La prevalencia de sobrepeso y obesidad, y el Z-IMC en niños de 2 a 5 años aumentó significativamente durante la pandemia.

Introduction. Childhood overweight and obesity are a public health problem. The onset of the COVID-19 pandemic may have contributed to this condition. The body mass index (BMI) Z-score has been accepted as an indicator for overweight and obesity diagnosis and follow-up. Objective. To assess whether the prevalence of overweight and obesity and the BMI Z-score in children aged 2 to 5 years increased during the pandemic. Population and methods. Retrospective, cohort study. Patients included were those seen at public health care facilities in the City of Buenos Aires (CABA), who were aged 2 to 5 years, had weight and height values recorded at 2 different visits, before and after the establishment of the preventive and mandatory social isolation policy. Patients' nutritional status (BMI Z-score) and the variation in this indicator between both visits were recorded. Results. A total of 3866 subjects were assessed; their average age was 3.4 ± 0.8 years; 48.1% were girls. The average interval between both visits was 14.3 ± 2.5 months. The prevalence of overweight/ obesity increased from 12.6% (95% CI: 11.6­13.6) to 20.9% (95% CI: 19.6­22.2), p < 0.001, and so did the BMI Z-score (0.4 ± 1.1 versus 0.8 ± 1.3, p < 0.001). Conclusion. The prevalence of overweight and obesity and the BMI Z-score in children aged 2 to 5 years increased significantly during the pandemic.

Seguridad alimentaria y nutricional de niños menores de 5 años: de la dimensión alimentaria a la nutricional / Food and Nutrition Security of Children under 5 Years: From Food to Nutritional Dimension / Segurança alimentar e nutricional de crianças menores de 5 anos: da dimensão alimentar à nutricional

Objetivo: analizar la asociación de características biológicas y sociales con la seguridad alimentaria y nutricional (san) de niños menores de 5 años con base en indicadores de percepción del hambre y antro-pométricos.Materiales y métodos: estudio transversal realizado en municipios brasileños que fueron priorizados para el desarrollo de acciones de prevención de la obesidad infantil en 2017/2018. La san se midió usando la Escala Brasileña de Inseguridad Alimentaria y se utilizaron los índices antropométricos Talla/Edad (T/E), Peso/Edad (P/E) y Peso/Talla (P/T). Las asociaciones se testaron por regresión de Poisson con varianza robusta.Resultados: de los 868 niños, el 24.3 % vivía en familias con inseguridad alimenta-ria y nutricional moderada-severa (ianm-s), el 7.0 % tenía T/E baja; el 7.8 % P/E alto, y el 14.4 %, P/T alto. Si bien la ianm-s se asoció con una amplia gama de factores negativos del contexto social, las prevalencias de las desviaciones antropométricas fueron mayores en menores de 2 años y cuando las madres tenían el mismo diagnóstico nutricional que el niño.Conclusión: a pesar de las prevalencias expresivas de ianm-sy desviaciones antropométricas, la ianm-s fue más pronunciada, especialmente en contextos sociales des-favorables. La san mostró un comportamiento diferente en sus dimensiones alimentaria y nutricional, tanto en términos de frecuencia como de determinación

Objective: To analyze the association between biological and social characteristics with the food and nutritional security (fns) of children aged <5 years based on hunger perception and anthropometric indicators. Materials and methods: This cross-sectional study was performed at Brazilian municipali-ties that have been prioritized for the development of actions aimed at preventing childhood obesity in 2017­2018. The fns aspect was analyzed with reference to the Brazilian Food Insecurity Scale and the anthropometric indices Height/Age (H/A), Weight/Age (P/A), and Weight/Height (P/H) were used. The associations were tested by the Poisson Regression with robust variance. Results: Of the 868 children, 24.3 % lived in families with moderate­severe food and nutritional insecurity, 7.0 % had low H/A, 7.8 % had high P/A, and 14.4% had high P/E. The moderate­severe food and nutritional insecurity was associ-ated with a wide range of negative factors in the social context, but the prevalence of anthropometric deviations was higher in children <2 years and when their mothers had the same nutritional diagno-sis. Conclusion: Despite the expressive prevalence of moderate­severe food and nutritional insecurity and anthropometric deviations, the former was more pronounced, especially under unfavorable social contexts. san displayed different behaviors in its food and nutritional dimensions, both in the terms of frequency and determination.

Objetivo: analisar a associação de características biológicas e sociais com a Segurança Alimentar e Nutricional (san) de crianças menores de 5 anos com base em indicadores de percepção da fome e antropométricos. Materiais e métodos: estudo transversal realizado em municípios brasileiros que foram priorizados para o desenvolvimento de ações de prevenção da obesidade infantil em 2017/2018. A san foi medida usando a Escala Brasileira de Insegurança Alimentar e utilizaram-se os índices antropométricos Estatura/Idade (E/I), Peso/Idade (P/I) e Peso/Estatura (P/E). As associações se testaram por Regressão de Poisson com variância robusta. Resultados: das 868 crianças, 24.3 % residiam em famílias com Insegurança Alimentar e Nutricional Moderada-Grave (ianm-g), 7.0 % tinham E/I baixa, 7.8 % P/I elevado e 14.4 % P/E elevado. Enquanto a ianm-gassociou-se a uma ampla gama de fatores negativos do contexto social, as prevalências dos desvios antropo-métricos foram maiores em menores de 2 anos e quando as mães tiveram o mesmo diagnóstico nutricional que a criança. Conclusão: apesar das prevalências expressivas de ianm-g e de desvios antropométricos, a ianm-gfoi mais acentuada, sobretudo em contextos sociais desfavoráveis. A san manifestou comportamento dife-rente nas suas dimensões alimentar e nutricional, tanto em termos de frequência quanto de determinação.

Avaliação da composição nutricional do composto lácteo à venda no mercado brasileiro / Evaluation of the nutritional composition of growing-up milk available in the Brazilian market

Introdução: A influência do consumo de composto lácteo na nutrição de crianças em primeira infância ainda é desconhecida, apesar de o produto movimentar um mercado multimilionário. Objetivo: Avaliar a composição nutricional do composto lácteo e a influência de seu consumo sobre as necessidades diárias de macronutrientes e energia de crianças pequenas. Métodos: A pesquisa foi dividida em três partes, sendo: a) avaliação da composição nutricional e ingredientes; b) comparação do composto lácteo brasileiro com uma proposta de padronização; c) cálculo de inadequação nutricional e influência do consumo de composto lácteo em crianças pequenas. Resultados: Foi possível categorizar o produto em três subgrupos, de acordo com os ingredientes, sendo: grupo 1 (soro de leite, açúcar e gordura vegetal), grupo 2 (adição de vitaminas e minerais) e grupo 3 (ampla lista de ingredientes, sem adição de açúcares e adição de bioativos). De forma geral, o composto lácteo tem como características: excesso de proteínas e açúcares de adição, predominância de gorduras saturadas, além de aditivos químicos. Em comparação com a proposta de composição ideal, o composto lácteo brasileiro excede todos os nutrientes analisados e, por fim, o consumo de dois copos de 200mL de composto lácteo por dia corresponde a 100% das necessidades diárias de proteína, sendo as crianças de 0 a 11 meses as mais prejudicadas. Conclusão: Independentemente do subgrupo e do ingrediente, o produto tem impacto negativo na saúde infantil, e quanto menor a idade de introdução, maior o impacto na saúde, podendo levar ao desenvolvimento de sobrepeso e obesidade.

Introduction: The influence of consuming growing-up milk on the nutrition of infants is still unknown, despite the product driving a multimillion-dollar market. Objective: To evaluate the nutritional composition of the growing-up milk and the influence of its consumption on the daily macronutrient and energy needs of young children. Methods: The research was divided into three parts, namely: a) evaluation of nutritional composition and ingredients; b) comparison of the Brazilian growing-up milk with a proposed standardization; c) calculation of nutritional inadequacy and the influence of growing-up milk consumption in young children. Results: It was possible to categorize the product into three subgroups based on ingredients, namely: group 1 (whey, sugar, and vegetable fat), group 2 (added vitamins and minerals), and group 3 (a wide range of ingredients, no added sugars, and addition of bioactives). Overall, the growing-up milk is characterized by excess protein and added sugars, a predominance of saturated fats, and the presence of chemical additives. Compared to the proposed ideal composition, the Brazilian growing-up milk exceeds all analyzed nutrients. Finally, consuming two 200mL glasses of growing-up milk per day corresponds to 100% of daily protein needs, with children aged 0 to 11 months being the most affected. Conclusion: Regardless of the subgroup and ingredient, the product has a negative impact on children's health, and the younger the age of introduction, the greater the impact on health, potentially leading to the development of overweight and obesity.

Intervenções não farmacológicas no manejo da obesidade infantil: uma overview / Non-pharmacological interventions in the management of childhood obesity: an overview / Intervenciones no farmacológicas en el tratamiento de la obesidad infantil: una visión general

Objetivo: Analisar na literatura científica a efetividade das intervenções não farmacológicas para o manejo da obesidade infantil. Método: Trata-se de uma revisão sistemática do tipo overview. As bases científicas para coleta de dados foram: Cinahl, Cochrane, Lilacs, Medline, Scopus, Scielo e Science direct, e todo o processo de seleção foi feito por pares e avaliado pelo teste Kappa. A análise dos estudos utilizou os instrumentos: AMSTAR para avaliação da qualidade metodológica, Robis 2.0 para avaliação do risco de viés, e o Sistema Grade para classificar nível de evidência. Resultado: 17 estudos foram considerados elegíveis, e avaliação das evidências demonstrou que as intervenções não farmacológicas são efetivas para o manejo da obesidade infantil, sendo classificadas pelo Sistema Grade com alto e moderado nível de evidência. Essas intervenções são caracterizadas como: comportamentais, educacional, familiar, nutricional e tecnológica e são capazes de promover mudanças no Índice de Massa Corporal e estilo de vida. Conclusão: As intervenções não farmacológicas são capazes de promover mudanças positivas quanto ao comportamento alimentar e manejo da obesidade, entretanto os resultados não são imediatos.

Objective: To analyze the effectiveness of non-pharmacological interventions for the management of childhood obesity in the scientific literature. Method: This is a systematic review of the overview type. The scientific databases for data collection were: Cinahl, Cochrane, Lilacs, Medline, Scopus, Scielo and Science direct, and the entire selection process was done by pairs and evaluated by Kappa test. The analysis of the studies used the instruments: AMSTAR to assess methodological quality, Robis 2.0 to assess risk of bias, and the Grade System to rank level of evidence. Results: 17 studies were considered eligible, and evaluation of the evidence showed that non- pharmacological interventions are effective for the management of childhood obesity, being classified by the Grade System with high and moderate level of evidence. These interventions are characterized as: behavioral, educational, family, nutritional, and technological, and are able to promote changes in Body Mass Index and lifestyle. Conclusion: Non-pharmacological interventions are able to promote positive changes in eating behavior and obesity management, but the results are not immediate.

Objetivo: Analizar la efectividad de las intervenciones no farmacológicas para el manejo de la obesidad infantil en la literatura científica. Método: Se trata de una revisión sistemática de tipo panorámica. Las bases de datos científicas para la recogida de datos fueron: Cinahl, Cochrane, Lilacs, Medline, Scopus, Scielo y Science direct, y todo el proceso de selección se realizó por parejas y se evaluó mediante el test de Kappa. En el análisis de los estudios se utilizaron los instrumentos AMSTAR para evaluar la calidad metodológica, Robis 2.0 para evaluar el riesgo de sesgo y el Grade System para clasificar el nivel de evidencia. Resultados: Se consideraron elegibles 17 estudios, y la evaluación de la evidencia mostró que las intervenciones no farmacológicas son efectivas para el manejo de la obesidad infantil, siendo clasificadas por el Sistema Grade con nivel de evidencia alto y moderado. Estas intervenciones se caracterizan por ser: conductuales, educativas, familiares, nutricionales y tecnológicas, y son capaces de promover cambios en el Índice de Masa Corporal y en el estilo de vida. Conclusiones: Las intervenciones no farmacológicas son capaces de promover cambios positivos en la conducta alimentaria y en el manejo de la obesidad, pero los resultados no son inmediatos.

Protocolo de intervenções nutricionais para o manejo da obesidade infantil na Atenção Primária à Saúde / Protocol to implement nutritional interventions for the management of childhood obesity in Primary Health Care

Objetivo: Construir e validar um protocolo de intervenções nutricionais para o manejo da obesidade infantil no âmbito da Atenção Primária à Saúde. Métodos: Trata-se de um estudo metodológico, organizado em três fases: elaboração de uma revisão sistemática do tipo overview, com uso das recomendações PRISMA, construção do protocolo clínico e validação do conteúdo com uso dos instrumentos AGREE II e AGREE-REX. Resultados: Foram incluídos 17 estudos para a construção do protocolo, indicando efetividade em intervenções com desfechos na redução significativa do IMC, mudança no comportamento e hábitos alimentares, aumento no nível de conhecimento sobre alimentação saudável. A avaliação do protocolo clínico obteve uma pontuação >70% e, conforme o parâmetro utilizado (≥50% qualidade alta), foi considerado adequado para implementação no campo da saúde da criança, mais especificamente no manejo da obesidade infantil. Conclusão: Um protocolo assistencial para o manejo da obesidade infantil no âmbito da Atenção Primária à Saúde representa de forma positiva uma estratégia sustentável e flexível com atuação de diversos atores sociais como profissionais da saúde e familiares, dentre outros, contribuindo para a redução de riscos de comorbidades associadas à obesidade e custos de saúde, bem como para promover comportamentos mais saudáveis na população pediátrica. Descritores: Atenção Primária à Saúde; Obesidade Infantil; Manejo da Obesidade; Protocolos Clínicos.

Objective: To create and validate a protocol to implement nutritional interventions for the management of childhood obesity in the Primary Health Care scope.Methods: This is a methodological study organized into three phases: elaboration of a systematic review of the "overview" type using the PRISMA recommendations; preparation of the clinical protocol; and content validation using the AGREE II and AGREE-REX instruments.Results: A total of 17 studies were included to create the protocol, indicating effectiveness in interventions with outcomes in a significant BMI reduction, change in eating behaviors and habits, and increase in the knowledge level about healthy eating. The clinical protocol assessment obtained a score >70% and, according to the parameter used (≥50% high quality), it was considered adequate for implementation in the children's health field, more specifically in the management of childhood obesity.Conclusion: A care protocol for the management of childhood obesity in the Primary Health Care scope positively represents a sustainable and flexible strategy with performance of several social actors such as health professionals and family members, among others, contributing to reducing risks of comorbidities associated with obesity and health costs, as well as to promoting healthier behaviors in the pediatric population. Descriptors: Primary Health Care; Pediatric Obesity; Obesity Management; Clinical Protocols.

Sobrepeso y obesidad en infancias de Bariloche, Argentina: más allá de la alimentación y la actividad física / Childhood overweight and obesity in Bariloche, Argentina: Beyond eating habits and physical activity

La incidencia de sobrepeso y obesidad es alarmante en el mundo. En Argentina son escasos los estudios multifactoriales a pesar de los altos índices de sobrepeso y obesidad en la población infantil (SOI). En este estudio evaluamos la prevalencia de SOI y sus factores de riesgo asociados desde una perspectiva multicausal: analizamos hábitos de sueño, uso de pantallas, estrés crónico en niños y sus cuidadores, problemas de relación social, alimentación y actividad física. De los 397 niños de primer y séptimo grado que completaron los cuestionarios, el 41 % presentó SOI. Los niños con obesidad mostraron realizar menos actividad física, tener un menor consumo de alimentos protectores, más riesgos de trastornos del sueño, mayores niveles de estrés crónico (tanto en los niños como en sus cuidadores) y mayor índice de rechazo entre pares. En la mayoría de los niños se encontró un uso generalizado de pantallas antes de acostarse. El presente estudio evidencia la diversidad de factores asociados a esta problemática y destaca la conveniencia de utilizar un enfoque multidimensional para abordar la obesidad en la infancia. Asimismo, los resultados de este trabajo sugieren la necesidad de considerar los hábitos de vida como estrategia preventiva y terapéutica para el tratamiento de esta enfermedad desde etapas tempranas.

The incidence of overweight and obesity is alarming worldwide. In Argentina, multifactorial studies are scarce despite the high rates of childhood overweight and obesity (OW/OB). In this study we assessed the prevalence of childhood OW/OB and the associated risk factors from a multicausal perspective: we analyzed sleep habits, screen use, chronic stress in children and their caregivers, social relationship problems, eating habits, and physical activity. Of the 397 first and seventh graders who completed the questionnaires, 41% had childhood OW/OB. In children with obesity, a lower level of physical activity, a lower consumption of protective foods, a higher risk for sleep disorders, higher levels of chronic stress (in both children and their caregivers), and higher rates of peer rejection were observed. Widespread use of screens before bedtime was noted in most children. This study evidences the diversity of factors associated with childhood OW/OB and highlights the convenience of a multidimensional approach to address it. In addition, the results of this study suggest the need to consider lifestyle habits as a preventive and therapeutic strategy for the management of OW/OB from early stages.

Morbilidad oculta por hipertensión arterial en adolescentes. Importancia del monitoreo ambulatorio de presión arterial / Hidden morbidity due to arterial hypertension in adolescents. Importance of ambulatory blood pressure monitoring

El diagnóstico de un niño o adolescente como hipertenso no es tarea fácil. El principal medio para el diagnóstico de hipertensión arterial sigue siendo la presión arterial tomada en el consultorio, pero por su escasa reproducibilidad, este método tiene algunas limitaciones. Existen otros menos usados en el medio pediátrico, pero más reproducibles y confiables, como el monitoreo ambulatorio de la presión arterial, el cual permite disminuir el subdiagnóstico de hipertensión arterial. La investigación se realizó a partir de un pesquisaje efectuado con el objetivo de identificar la morbilidad oculta de hipertensión arterial en adolescentes con exceso de peso, en el área de salud del Policlínico «Chiqui Gómez Lubián», Santa Clara, Villa Clara. El caso reviste importancia para la Atención Primaria de Salud, promueve la utilización de un método diagnóstico que mejora la correcta clasificación y tratamiento de la hipertensión en edades tempranas para contribuir a la prevención de complicaciones posteriores

Diagnosing a child or an adolescent as hypertensive is not an easy task. The main way to diagnose arterial hypertension continues to be at the doctor´s office, but due to its poor reproducibility, this method has some limitations. There are other less used methods in the pediatric setting, but are more reproducible and reliable, such as ambulatory blood pressure monitoring, which makes it possible to reduce the underdiagnosis of arterial hypertension. We present a case of a male adolescent who was detected during a screening, with the objective of identifying hidden morbidity of arterial hypertension in overweight adolescents, in the health area at "Chiqui Gómez Lubián" Polyclinic, in Santa Clara, Villa Clara. The case is of great important for primary health care, promotes the use of a diagnosis method that improves the correct classification and treatment of hypertension at an early age and contributes to the prevention of subsequent complications

Sobrepeso y obesidad en escolares de la Región de Magallanes y Antártica Chilena, Chile, (2009 ­ 2019), y comparación de dos metodologías para el diagnóstico / Overweight and obesity in schoolchildren in the Magallanes and Chilean Antarctica Region, Chile, (2009 - 2019), and comparison of two methodologies for diagnosis

Introducción. En Chile la prevalencia de obesidad total en población escolar alcanza al 31% y la obesidad severa al 10,8%. La Región de Magallanes y Antártica Chilena, es una de las más afectadas por esta epidemia. El diagnóstico nutricional confiable y una intervención oportuna pueden evitar que los niños enfermen y deterioren su calidad de vida. Objetivo: Analizar la tendencia del estado nutricional de escolares de la Región de Magallanes, según datos reportados por la Junta Nacional de Auxilio Escolar y Becas, JUNAEB, entre 2009-2019 y comparar resultados del año 2010 con un estudio propio. Materiales y métodos. Se analizó el estado nutricional de 71.334 escolares de la Región de Magallanes y Antártica Chilena por nivel educacional y variables demográficas, según información de JUNAEB. Luego se compararon los resultados de escolares de 1º básico del año 2010, obtenidos a través de dos metodologías: fuente secundaria, Encuesta JUNAEB, y fuente primaria, estudio antropométrico realizado en la misma región y año. Resultados. Según datos de JUNAEB el exceso ponderal se incrementó en escolares de la región en 4,4 % entre 2009 y 2019, el grupo más afectado fue 1º básico. En el año 2010 la prevalencia de obesidad para escolares de 1º básico según JUNAEB fue 21,8% y según estudio regional propio fue 25,7%. Conclusiones. La malnutrición por exceso afecta al 53,8% de los escolares de la Región de Magallanes y podría ser mayor, considerando que la información censal podría estar subestimando el sobrepeso y obesidad. Es urgente intervenir para evitar perpetuar esta epidemia(AU)

Introduction. In Chile the prevalence of total obesity in school population reaches 31% and severe obesity 10.8%. The Magallanes and Chilean Antarctica Region is one of the most affected by this epidemic. Reliable nutritional diagnosis and timely intervention can prevent children from getting sick and deteriorating their quality of life. Objective. To analyze the trend of nutritional status of schoolchildren in the Magallanes Region, according to data reported by the National Board of School Aid and Scholarships, JUNAEB between 2009-2019 and compare results from 2010 with our own study. Materials and methods. The nutritional status of 71,334 schoolchildren in the Magallanes Region and Chilean Antarctica was analyzed by educational level and demographic variables, according to information from JUNAEB. Then, the results of schoolchildren in 1st grade in 2010 were compared, obtained through two methods: secondary source, JUNAEB survey, and primary source, anthropometric study carried out in the same region and year. Results. According to JUNAEB data, overweight increased in school children in the region by 4.4% between 2009 and 2019, the most affected group was 1st grade. In 2010 the prevalence of obesity for 1st grade schoolchildren according to JUNAEB was 21.8% and according to our own regional study it was 25.7%. Conclusions. Excess malnutrition affects 53.8% of school children in the Magallanes Region and could be higher, considering that census information could be underestimating overweight and obesity. It is urgent to intervene to avoid perpetuating this epidemic(AU)

Estado nutricio de niños del noroeste de México pre y post pandemia por COVID-19 / Nutritional status of children in northwest Mexico pre and post COVID-19 pandemic

Introducción. Mundialmente se observaron consecuencias negativas en la salud por el aislamiento social durante la pandemia de COVID-19; el sobrepeso y la obesidad mostraron tendencias crecientes. Objetivo. Analizar los cambios en el sobrepeso, obesidad y alimentación de escolares del noroeste de México antes y después del aislamiento por COVID-19. Materiales y métodos. Se colectaron y analizaron el peso, talla y circunferencia de cintura de escolares del noroeste de México pre y post pandemia por COVID 19 (n=479 y n=820). Además, se analizaron los cambios en la alimentación en una submuestra de 203 y 179 escolares pre y post pandemia, respectivamente. Resultados. La edad promedio de los escolares en 2019 fue 8,9 ±1,75 y en el 2022 de 9,1 ± 1,54 años. Se observó un aumento de 6,2 puntos porcentuales en la prevalencia de sobrepeso y obesidad y diferencias en la distribución de las categorías del estado nutricio (p=0,049) entre los dos periodos. También, se observaron cambios en la adiposidad central con un aumento de 3 centímetros en la circunferencia de cintura (p=0,001; 62,6 y 65,6 cm). El índice de alimentación saludable (IAS) mostró una alimentación poco saludable durante los dos periodos. Conclusiones. El aumento en las prevalencias de sobrepeso y obesidad, así como de obesidad central durante la emergencia epidemiológica, indicaron un deterioro del estado nutricio de los escolares, que coincide con los reportes en poblaciones a nivel mundial y en Latinoamérica; los resultados resultan preocupantes dada la problemática antes de la emergencia(AU)

Introduction. Negative health consequences due to social isolation during the COVID-19 pandemic were observed worldwide; overweight and obesity showed increasing trends. Objective. To analyze the changes in overweight, obesity and diet of schoolchildren in northwest Mexico before and after lockdown due to COVID-19. Materials and methods. Weight, height, and waist circumference of schoolchildren (n=479 pre-pandemic and n=820 post-pandemic) were collected in public schools located in medium to high marginalization neighborhoods. In the same periods dietary data was collected from a subsample of 203 and 179 schoolchildren, respectively. Results. The average age of schoolchildren in 2019 was 8,9 ±1,75 and 9,1 ± 1,54 in 2022. An increase in percentage of 6,2 was observed in the overweight plus obesity prevalence and a significant difference in the distribution of nutritional status (p=0,049) between the two periods. In addition, changes in central adiposity were observed, with an increase of 3 centimeters in waist circumference (p=0,001; 62,6 and 65,6 cm). The healthy eating index (HAI) classified the diet of schoolchildren as unhealthy during both periods. Conclusions. The increase in the prevalence of overweight and obesity, as well as central adiposity is worrying given that they were already a health problem before the COVID 19 confinement(AU)

Body morphology and bone age in girls with obesity and without obesity aged 8 to 15 years: a cross-sectional study / Morfologia corporal e idade óssea em meninas com obesidade e sem obesidade de 8 a 15 anos: um estudo transversal

Introduction: childhood obesity is one of the main public health problems worldwide, leading to health status repercussions and growth and maturation process implications in both children and adolescents. Objective: the aim of this study was to verify body morphology and bone age variations in girls with obesity and without obesity. Methodology: this comprises a cross-sectional study conducted with 140 girls aged 8 to 15 years old, 70 with obesity and 70 without obesity. Hip and waist circumferences, body mass, height and and Body Mass Index (BMI) were determined. For maturation status determinations, bone ages were determined by a left wrist and hand radiography employing the Fels method. Results: the findigs indicate significant correlations between nutritional and maturation statuses (r=0.80; p˂0.01). Girls with obesity presented higher weight and BMI values, larger waist and hip circumferences and more advanced bone age compared to girls without obesity (p˂0.01). The same significant differences (p˂0.01) were noted in the contrasting maturational group analysis, where girls presenting advanced maturation always exhibited the highest parameter values. Conclusion: nutritional status is associated to maturation status, and girls with obesity exhibit more advanced bone age than girls without obesity.

Introdução: a obesidade infantil é um dos principais problemas de saúde pública mundial, com repercussões no estado de saúde e implicações no processo de crescimento e maturação de crianças e adolescentes. Objetivo: verificar a variação da morfologia corporal e da idade óssea em meninas com e sem obesidade. Metodologia: estudo transversal conduzido com 140 meninas de 8 a 15 anos de idade, sendo 70 meninas com obesidade e 70 sem obesidade. Foram mensuradas as circunferências do quadril e da cintura, massa corporal, altura e o Índice de Massa Corporal (IMC). Para o status maturacional foi determinada a idade óssea por meio de radiografia de punho e mão esquerdos pelo Método Fels. Resultados: os resultados apontaram a existência de correlação entre o status nutricional e o status maturacional (r=0,80; p˂0,01). As meninas com obesidade apresentaram maior peso, IMC mais elevado, circunferências maiores e idade óssea mais avançada quando comparadas às meninas sem obesidade (p˂0,01). Na análise dos grupos maturacionais contrastantes as mesmas diferenças se apresentaram com valores significativos (p˂0,01), sendo as meninas avançadas maturacionalmente sempre com valores superiores. Conclusão: o status nutricional apresentou correlação com o status maturacional, e as meninas com obesidade apresentam idade óssea mais avançada que aquelas sem obesidade

Entornos escolares saludables / healthy school environments

El sobrepeso y la obesidad en niños, niñas y adolescentes (NNyA) así como en adultos, es una epidemia en aumento que está tomando proporciones alarmantes en todo el mundo y representa uno de los principales problemas de salud pública que requiere respuestas de los Estados en forma urgente1 . El sobrepeso y la obesidad muestran una curva ascendente especialmente preocupante en NNyA, en quienes el crecimiento es más acelerado que en personas adultas. El sobrepeso y la obesidad afectan tanto la salud psico-física inmediata de NNyA, como el nivel educativo que pueden alcanzar y su calidad de vida. Asimismo, los NNyA con sobrepeso y obesidad tienen mayores probabilidades de seguir siendo personas obesas en la edad adulta y presentan mayor riesgo de sufrir enfermedades no transmisibles (ENT), como las cardiovasculares, la diabetes o el cáncer2. Más información detallada sobre la evolución de la epidemia de obesidad en NNyA a nivel internacional y en Argentina, así como su impacto en la salud y en la economía de los países se desarrolló en el reciente informe publicado por la Secretaria de Gobierno de Salud en colaboración con UNICEF3. En dicho informe se analizaron el peso y la talla de NNyA de 0 a 18 años que accedieron a la atención del sistema público de salud del país y se concluyó que en Argentina, en sintonía con la reconocida "transición nutricional" global, el sobrepeso y la obesidad en NNyA representa la forma más prevalente de malnutrición. Esto se evidencia en el hecho de que entre los más de 3 millones de NNyA atendidos en el sector público del sistema de salud argentino en 2016, 31,1% tenían malnutrición por exceso (sobrepeso y obesidad) y 8,1% malnutrición por carencia (bajo peso). En la actualidad, y como consecuencia de numerosos cambios sociales, culturales y económicos, como por ejemplo los cambios en los modelos de producción de alimentos, su disponibilidad, asequibilidad, comercialización y marketing, así como por la escasa práctica de actividad física, los NNyA crecen y se desarrollan a menudo en entornos obesogénicos. Un entorno obesogénico es aquel que fomenta el consumo excesivo de kilocalorías y nutrientes críticos como azúcares, grasas y sodio, además de ofrecer múltiples barreras para el desarrollo de actividad física y fomentar el comportamiento sedentario4. Así, la falta de regulación que promueva entornos más saludables, ha favorecido en las últimas décadas al crecimiento del sobrepeso y la obesidad. Las respuestas conductuales y biológicas de NNyA ante un entorno obesogénico pueden estar determinadas por procesos anteriores incluso a su nacimiento, lo que empuja a un número cada vez mayor de NNyA hacia la obesidad, si siguen una alimentación de baja calidad nutricional y no realizan la actividad física recomendada1 . Existen pruebas convincentes de que la publicidad y la comercialización de alimentos y bebidas con alto contenido de sodio, grasas, azúcares y kilocalorías, pero deficientes en micronutrientes, pueden repercutir en las preferencias alimentarias, el comportamiento de compra y el consumo de NNyA. La comercialización y provisión en las escuelas de alimentos y bebidas con altos niveles de azúcar, grasa, sal y bajo valor nutricional, también influyen en los patrones y hábitos de consumo en niños y niñas5, 6, 7, 8. La prevención y el tratamiento de la obesidad exige un enfoque intersectorial e intergubernamental y en el que las políticas de todos los sectores tengan en cuenta sistemáticamente la salud, eviten los efectos sanitarios nocivos y, por tanto, mejoren la salud de la población y la equidad. La Organización Mundial de la Salud (OMS) y otros organismos internacionales han publicado en los últimos años, numerosos documentos que, en base a evidencia científica, establecen un conjunto de medidas para regular los entornos obesogénicos y los productos, de modo de fomentar hábitos saludables y así detener el crecimiento de esta epidemia2, 9, 10. Dentro de estas medidas recomendadas, una que resulta clave y que cuenta con alto consenso a nivel internacional es la regulación de los entornos escolares para promover la nutrición adecuada y la actividad física. Sólo a través de una serie de medidas (intervención multicomponente) de demostrada eficacia que aborde integralmente aspectos nutricionales y de actividad física en las instituciones escolares, se conseguirán las transformaciones necesarias para fomentar hábitos saludables y mejorar los patrones de conducta de NNyA. El objetivo del presente documento es establecer un conjunto de recomendaciones que, basadas en las mejores evidencias científicas disponibles, constituyan los estándares para guiar el proceso de sanción de leyes e implementación de programas efectivos, para transformar los entornos obesogénicos en entornos escolares saludables. Estos estándares están dirigidos a legisladores y decisores políticos tanto del nivel nacional como provincial y municipal así como también a organizaciones académicas y de la sociedad civil que trabajen en la temática.

Protocolo Clínico e Diretrizes Terapêuticas (PCDT) de tratamento medicamentoso da obesidade em crianças e adolescentes com doze a vinte e um anos de idade no Estado de Goiás ­ versão janeiro de 2023 / Clinical Protocol and Therapeutic Guidelines (PCDT) for drug treatment of obesity in children and adolescents aged twelve to twenty-one years in the State of Goiás ­ January 2023 version

A obesidade é um transtorno crônico, complexo e multifatorial, envolve fatores ambientais, estilo de vida, hormonais e genéticos, acomete indivíduos de todas as idades e quanto mais cedo ocorre, maiores são os riscos à saúde. Uma criança com obesidade tem 80% chance de tornar-se um adulto com obesidade (FREEDMAN et al., 2007). Tratamento medicamentoso está aprovado a partir do IMC> 27 kg/m2 associado a comorbidades ou ≥ 30 kg/m2 mesmo na ausência de comorbidades. Liraglutida é o único medicamento aprovada para uso em adolescentes a partir dos 12 anos de idade com peso corporal maior que 60 kg e IMC correspondendo a 30 kg/m² para adultos

Clinical and genetic analysis of a child with early-onset severe obesity / 中华医学遗传学杂志

OBJECTIVE@#To explore the clinical phenotype and genetic etiology of a child with early-onset severe obesity.@*METHODS@#A child who presented at the Department of Endocrinology, Hangzhou Children's Hospital on August 5, 2020 was selected as the study subject. Clinical data of the child were reviewed. Genomic DNA was extracted from peripheral blood samples of the child and her parents. Whole exome sequencing (WES) was carried out on the child. Candidate variants were verified by Sanger sequencing and bioinformatic analysis.@*RESULTS@#This child was a 2-year-and-9-month girl featuring severe obesity with hyperpigmentation on the neck and armpit skin. WES revealed that she has harbored compound heterozygous variants of the MC4R gene, namely c.831T>A (p.Cys277*) and c.184A>G (p.Asn62Asp). Sanger sequencing confirmed that they were respectively inherited from her father and mother. The c.831T>A (p.Cys277*) has been recorded by the ClinVar database. Its carrier frequency among normal East Asians was 0.000 4 according to the 1000 Genomes, ExAC, and gnomAD databases. Based on the guidelines from the American College of Medical Genetics and Genomics (ACMG), it was rated as pathogenic. The c.184A>G (p.Asn62Asp) has not been recorded in the ClinVar, 1000 Genomes, ExAC and gnomAD databases. Prediction using IFT and PolyPhen-2 online software suggested it to be deleterious. Based on the guidelines from the ACMG, it was determined as likely pathogenic.@*CONCLUSION@#The c.831T>A (p.Cys277*) and c.184A>G (p.Asn62Asp) compound heterozygous variants of the MC4R gene probably underlay the early-onset severe obesity in this child. Above finding has further expanded the spectrum of MC4R gene variants and provided a reference for the diagnosis and genetic counseling for this family.

Influence of rs2587552 polymorphism of DRD2 gene on the effect of a childhood obesity intervention: A prospective, parallel-group controlled trial / 北京大学学报(医学版)

OBJECTIVE@#To explore the association between rs2587552 polymorphism (has a strong lin-kage disequilibrium with rs1800497 which had been found in many studies to be related to obesity, r2=0.85) of DRD2 gene and the effect of a childhood obesity intervention in Chinese population, and provide a scientific basis for future personalized childhood obesity intervention based on genetic background.@*METHODS@#From a multi-center cluster randomized controlled trial studying the effect of a childhood obesity intervention, we enrolled 382 children from 8 primary schools (192 and 190 children from intervention and control groups, respectively) in Beijing as study subjects. Saliva was collected and DNA was extracted to detect the rs2587552 polymorphism of DRD2 gene, and the interactions between the gene and study arms on childhood obesity indicators [including body weight, body mass index (BMI), BMI Z-score, waist circumference, hip circumference, waist-to-hip ratio, waist-to-height ratio, and body fat percentage] were analyzed.@*RESULTS@#No association was found between rs2587552 polymorphism and the changes in hip circumference or body fat percentage in the intervention group (P>0.05). However, in the control group, children carrying the A allele at DRD2 rs2587552 locus showed a greater increase in hip circumference and body fat percentage compared with those not carrying A allele (P < 0.001). There were interactions between rs2587552 polymorphism of DRD2 gene and study arms on the changes in hip circumference and body fat percentage (P=0.007 and 0.015, respectively). Compared with the control group, children in the intervention group carrying the A allele at DRD2 rs2587552 locus showed decrease in hip circumference by (-1.30 cm, 95%CI: -2.25 to -0.35, P=0.007) and decrease in body fat percentage by (-1.34%, 95%CI: -2.42 to -0.27, P=0.015) compared with those not carrying A allele. The results were consistent between the dominant model and the additive model (hip circumfe-rence: -0.66 cm, 95%CI: -1.28 to -0.03, P=0.041; body fat percentage: -0.69%, 95%CI: -1.40 to 0.02, P=0.056). No interaction was found between rs2587552 polymorphism and study arms on the changes in other childhood obesity-related indicators (P>0.05).@*CONCLUSION@#Children carrying the A allele at rs2587552 polymorphism of DRD2 gene are more sensitive to intervention and showed more improvement in hip circumference and body fat percentage after the intervention, suggesting that future personalized childhood obesity lifestyle intervention can be carried out based on the rs2587552 polymorphism of DRD2 gene.

Association of outdoor artificial light at night exposure with overweight and obesity among children and adolescents aged 9 to 18 years in China / 北京大学学报(医学版)

OBJECTIVE@#To analyze the association between outdoor artificial light-at-night (ALAN) exposure and overweight and obesity among children and adolescents aged 9 to 18 years in China.@*METHODS@#Using follow-up data of 5 540 children and adolescents aged 9 to 18 years conducted from November 2019 to November 2020 in eight provinces of China, latitude and longitude were determined based on school addresses, and the mean monthly average nighttime irradiance at the location of 116 schools was extracted by the nearest neighbor method to obtain the mean outdoor ALAN exposure [unit: nW/(cm2·sr)] for each school. Four indicators of overweight and obesity outcomes were included: Baseline overweight and obesity, persistent overweight and obesity, overweight and obesity progression and overweight and obesity incidence. Mixed effects Logistic regression was used to explore the association between ALAN exposure levels (divided into quintiles Q1-Q5) and baseline overweight and obesity, persistent overweight and obesity, overweight and obesity progression and overweight and obesity incidence. In addition, a natural cubic spline function was used to explore the exposure response association between ALAN exposure (a continuous variable) and the outcomes.@*RESULTS@#The prevalence of baseline overweight and obesity, persistent overweight and obesity, overweight and obesity progression and overweight and obesity incidence among the children and adolescents in this study were 21.6%, 16.3%, 2.9% and 12.8%, respectively. The OR value for the association between ALAN exposure and baseline overweight and obesity was statistically significant when ALAN exposure levels reached Q4 or Q5, 1.90 (95%CI: 1.26-2.86) and 1.77 (95%CI: 1.11-2.83), respectively, compared with the children and adolescents in the Q1 group of ALAN exposure. Similar to the results for baseline overweight and obesity, the OR values for the association with persistent overweight and obesity were 1.89 (95%CI: 1.20-2.99) and 1.82 (95%CI: 1.08-3.06) when ALAN exposure levels reached Q4 or Q5, respectively, but none of the OR values for the association between ALAN and overweight and obesity progression and overweight and obesity incidence were statistically significant. Fitting a natural cubic spline function showed a non-linear trend between ALAN exposure and persistent overweight and obesity.@*CONCLUSION@#There is a positive association between ALAN exposure and overweight and obesity in children and adolescents, and the promotion of overweight obesity in children and adolescents by ALAN tends to have a cumulative effect rather than an immediate effect. In the future, while focusing on the common risk factors for overweight and obesity in children and adolescents, there is a need to improve the overweight and obesity-causing nighttime light exposure environment.

Progress in research of etiology of childhood obesity based on interaction between genes and environment / 中华流行病学杂志

Childhood obesity is a global public health problem, which can not only endangers children's health, but also might be an important cause of chronic diseases in adulthood. In recent years, with the in-depth development of precision medicine research, more and more research evidences have shown that there are interactions between environmental factors, such as early intrauterine environment, children's diet, physical activity and children's gene factor on the incidence of childhood obesity, which can result in or inhibit the incidence and development of childhood obesity. This paper summarizes the progress in research in this field to reveal the effects and potential mechanisms of genetic factors and environmental factors on the incidence of childhood obesity in order to provide reference for the precise prevention and control of childhood obesity under different genetic backgrounds.