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1.
Rev. cuba. med. mil ; 47(1): 2-11, ene.-mar. 2018. tab
Article in Spanish | LILACS, CUMED | ID: biblio-960589

ABSTRACT

Introducción: el sangrado digestivo alto constituye uno de los síndromes más frecuentes en servicios de urgencias. La endoscopia oral y los medicamentos antiácidos y protectores de la mucosa gástrica, hacen menos frecuente el empleo de intervenciones quirúrgicas en el manejo del paciente con sangrado digestivo alto. La necesidad del tratamiento quirúrgico no siempre puede obviarse. Objetivo: describir las características clínicas de los pacientes con sangrado digestivo alto atendidos en el Hospital Militar Dr. Joaquín Castillo Duany. Métodos: estudio descriptivo transversal. Universo constituido por 92 pacientes con diagnóstico de sangrado digestivo alto. Variables caracterizadas: edad, sexo, tratamiento médico empleado, técnica quirúrgica utilizada, complicaciones posquirúrgicas y estadía hospitalaria. Resultados: el sangrado digestivo alto fue más frecuente en hombres, con más de 40 años de edad, se les aplicó tratamiento médico, la modalidad más frecuente fue la combinación de antiácidos. Se realizó tratamiento endoscópico al 3,2 por ciento de los pacientes, fueron intervenidos quirúrgicamente el 5,4 por ciento. La mitad de los operados padecía úlcera péptica gástrica. La técnica quirúrgica más empleada fue la gastrostomía y gastrorrafia. La estadía hospitalaria fue menor de 5 días. Conclusiones: se evidenció predominio del sangrado digestivo alto en el sexo masculino y en mayores de 40 años. El tratamiento endoscópico y las intervenciones quirúrgicas representaron un bajo porcentaje. La estadía hospitalaria fue más prolongada en pacientes con complicaciones. Los hallazgos en los que más difieren otras investigaciones radican en el incremento del empleo de la endoscopia oral, en combinación con el uso de antisecretores y en las variantes de técnicas quirúrgicas empleadas(AU)


Introduction: upper Digestive Bleeding is one of the most frequent syndromes in emergency services. Oral endoscopy, antacid and protective gastric mucosal medications make the use of surgical interventions less common in the management of upper digestive bleeding patients. However, the need for surgical treatment cannot always be overlooked. Objective: to describe the clinical characteristics of patients with upper digestive bleeding treated at the Military Hospital Dr. Joaquín Castillo Duany. Methods: cross-sectional descriptive study. A universe of 92 patients with a diagnosis of upper digestive bleeding. Variables characterized: Age, sex, medical treatment, surgical technique used, postoperative complications, and hospital stay. Results: upper digestive bleeding was more frequent in men and in patients over 40 years old. In patients in whom medical treatment was applied, the most frequent modality was the combination of anti-H2 antihistamines and proton pump inhibitors. Endoscopic treatment was performed in 3.2 percent of patients, and 5.4 pèrcent was operated on. Half of the patients underwent gastric peptic ulcer, and the most commonly used surgical technique was gastrostomy. The predominant hospital stay was less than 5 days(AU)


Subject(s)
Humans , Male , Adult , Endoscopy, Gastrointestinal/adverse effects , Gastrointestinal Hemorrhage/diagnosis , Antacids/therapeutic use , Peptic Ulcer Hemorrhage/surgery , Epidemiology, Descriptive , Cross-Sectional Studies
2.
Medisan ; 19(5)mayo.-mayo 2015.
Article in Spanish | LILACS, CUMED | ID: lil-747718

ABSTRACT

En la actualidad constituye un verdadero problema científico la diversidad de criterios sobre las características epidemiológicas, clínicas y quirúrgicas de la hemorragia digestiva alta no varicosa, debido a sus altas tasas de letalidad y mortalidad, por cuanto resulta de gran importancia identificar los factores pronósticos de complicaciones y decesos, inherentes a esta entidad clínica, a fin de elaborar un protocolo de actuación y buenas prácticas, una vez reconocidas las condiciones modificables que disminuyan el número de fallecimientos por esta causa, sobre todo en la población envejecida como grupo vulnerable, de donde se derivaría la trascendencia de su impacto médico social. Todo ello justifica la necesidad de profundizar en los principales aspectos cognoscitivos relacionados con este tema, puesto que solo contando con equipos de trabajo altamente especializados, podrá elevarse la calidad asistencial y, con esa premisa, el índice de supervivencia de quienes presenten ese tipo de sangrado por enfermedad ácido péptica.


At present the diversity of criteria on the epidemiological, clinical and surgical characteristics of the high digestive hemorrhage non varicose constitutes a true scientific problem, due to their high lethality and mortality rates, so that it is of great importance to identify the complications prognosis factors and death, inherent to this clinical entity, in order to elaborate a performance protocol and good practices, once the modifiable conditions which decrease the number of deaths due to this cause are recognized, mainly in the aged population as vulnerable group, from where the transcendency of its social medical impact would be derived . All this justifies the necessity to deepen in the main cognitive aspects related to this topic, since just having highly specialized working teams, it will be able to rise the assistance quality and, with that premise, the survival index of those who suffer from that type of bleedding caused by acid peptic disease.


Subject(s)
Peptic Ulcer Hemorrhage , Endoscopy, Digestive System , Peptic Ulcer Hemorrhage/surgery , Peptic Ulcer Hemorrhage/mortality
4.
Medisan ; 14(5)jun.-jul. 2010. tab
Article in Spanish | LILACS | ID: lil-576662

ABSTRACT

Introducción: El sangrado digestivo alto es una emergencia medicoquirúrgica frecuente, que suele ser diagnosticado mediante la endoscopia por vía oral y la radiografía de esófago, estómago y duodeno. Objetivo: Describir los resultados diagnósticos y terapéuticos en los pacientes ingresados por esa causa en el Servicio de Cirugía General del Hospital General Docente Dr Juan Bruno Zayas Alfonso de Santiago de Cuba durante el bienio 2007-2008. Métodos: Se hizo un estudio descriptivo, transversal y retrospectivo de 88 pacientes hospitalizados con esa afección, tomando en cuenta variables seleccionadas. Resultados: La endoscopia por vía oral se efectuó a 56,8 por ciento de la serie y reveló que tanto la úlcera duodenal como las gastritis agudas y crónicas fueron las gastropatías predominantes según clasificación de Forrest III; en la radiografía de esófago, estómago y duodeno se observaron más comúnmente los pliegues engrosados. Excepto 6 pacientes (6,8 por ciento) que fallecieron, los restantes mejoraron con el tratamiento durante una corta estadía. Conclusiones: A pesar de la efectividad de la prueba endoscópica, aún no puede realizarse a todas las personas con sangrado digestivo alto.


ntroduction: The upper digestive bleeding is a frequent medical surgical emergency that is usually diagnosed by means of oral endoscopy and the esophagus, stomach and duodenum x-ray. Objective: To describe the diagnostic and therapeutic results in the patients admitted by that cause in the General Surgery Service of Dr Juan Bruno Zayas Alfonso Teaching General Hospital in Santiago de Cuba during the biennium 2007-2008. Methods: A descriptive, cross-sectional and retrospective study of 88 patients hospitalized with that affection was carried out, taking into account selected variables. Results: The oral endoscopy was made to 56,8 per cent of patients of the series and revealed that both duodenal ulcer and acute and chronic gastritis were the predominant gastropathies according to classification of Forrest III. In the esophagus, stomach and duodenum x-ray thickened folds were the most commonly observed. Except for 6 patients (6,8 per cent) who died, the rest of them improved with the treatment during a short stay. Conclusions: In spite of the effectiveness of the endoscopic test, it cannot still be made to all the people with upper digestive bleeding.


Subject(s)
Humans , Endoscopy , Esophageal and Gastric Varices , Gastritis , Gastrointestinal Hemorrhage/surgery , Secondary Care , Peptic Ulcer Hemorrhage/surgery , Peptic Ulcer/surgery , Cross-Sectional Studies , Epidemiology, Descriptive , Retrospective Studies
5.
The Korean Journal of Gastroenterology ; : 298-308, 2009.
Article in Korean | WPRIM | ID: wpr-101886

ABSTRACT

Peptic ulcer (PU) bleeding is the main cause of non-variceal gastrointestinal bleeding. Negative outcomes include re-bleeding and death, and many of the deaths are associated with decompensation of coexisting medical conditions precipitated by acute bleeding event. Accurate analysis of risk for clinical features can help physician to decide treatment modality. Endoscopy can detect bleeding stigmata and perform therapeutic hemostasis. Proton pump inhibitor (PPI) compared with placebo or H2RA reduces mortality following PU bleeding among patients with high-risk endoscopic findings, and reduces re-bleeding rates and surgical intervention. PPI treatment initiated prior to endoscopy in upper gastrointestinal (UGI) bleeding significantly reduces the proportion of patients with stigmata of recent hemorrhage (SRH) at index endoscopy but does not reduce mortality, re-bleeding or the need for surgery. The strategy of giving oral PPI before and after endoscopy, with endoscopic hemostasis for those with major SRH, is likely to be the most cost-effective. The treatment of H. pyori infection was found to be more effective than anti-secretory therapy in preventing recurrent bleeding from PU. H. pyori eradication alone and eradication followed by misoprostol (with switch to PPI, if misoprostol is not tolerated) are the two most cost-effective strategies to prevent ulcer bleeding among H. pyori-infected NSAID users, although the data cannot exclude PPIs also being cost-effective treatment. This review focuses specifically on the current treatment of patients with acute bleeding from a peptic ulcer.


Subject(s)
Humans , Anti-Ulcer Agents/therapeutic use , Endoscopy, Gastrointestinal , Gastrointestinal Hemorrhage/diagnosis , Helicobacter Infections/diagnosis , Helicobacter pylori , Hemostasis, Endoscopic , Misoprostol/therapeutic use , Peptic Ulcer/surgery , Peptic Ulcer Hemorrhage/surgery , Proton Pump Inhibitors/therapeutic use
6.
Sudan Journal of Medical Sciences. 2008; 3 (4): 339-341
in English | IMEMR | ID: emr-90454

ABSTRACT

We report a 46 years-old man who had severe bleeding from a posterior duodenal ulcer [DU] that was diagnosed but could not be treated endoscopically in another health facility. He went into shock as he was being admitted to the casualty at Khartoum North Teaching Hospital [KNTH]. His haemoglobin [Hb] dropped to five gram/dl. He required resuscitation and transfusion of six units of blood overnight. Emergency surgery was performed. Over sewing [OS] of the ulcer was done and the stenosed first part of duodenum was closed transversely [pyloroplasty]. No acid-reducing procedure [ARP] was done. The patient received anti- helicobacter therapy via the intravenous route preoperatively and continued postoperatively. This was later given orally after he started taking by mouth. He made an uneventful recovery with no recurrence of bleeding and was discharged home one week latter. Endoscopy was done at KNTH six weeks later. This showed complete healing of the ulcer with no evidence of Helicobacter pylori in the biopsies taken. We found simple OS of the bleeding DU together with anti-helicobacter therapy safe, efficient, and not associated with re-bleeding. We discuss the rationale of this simple treatment. We propose the need for a randomized controlled study comparing it with acid-reducing procedure [ARP] as options in the surgical treatment of bleeding DU


Subject(s)
Humans , Male , Duodenal Ulcer/drug therapy , Duodenal Ulcer/diagnosis , Duodenal Ulcer/surgery , Endoscopy/statistics & numerical data , Peptic Ulcer Hemorrhage/diagnosis , Peptic Ulcer Hemorrhage/surgery , Peptic Ulcer Hemorrhage/drug therapy , Helicobacter pylori
7.
University of Aden Journal of Natural and Applied Sciences. 2008; 12 (1): 165-177
in English | IMEMR | ID: emr-90703

ABSTRACT

We aimed to explore and analyze current status of bleeding peptic ulcers in surgical patients. The study was carried out at the Surgical Department of Al-Gamhouria Teaching Hospital, Aden-Yemen. It was divided into 2 parts. Group [A] patients, admitted with bleeding peptic ulcers during the period May 1998 to April 2003, were retrospectively evaluated, and the prospective group [B] that included patients admitted during the period May 2003 to April 2006. One hundred and twenty patients were enrolled in the study; 75% were in group [A] and 25% in [B]. Men were [103] and women [17], with a ratio of [6.1:1]. Overall mean age was 43.4 years [ranging 17 to 70 years] with 23 patients [19.17%] over 60 years. Endoscopic activity within the first 24 hours in group [A] was [55.56%] and zero in [B]. Ratio of bleeding duodenal to gastric ulcers was [2:1]. Bleeding was massive and /or recurred in [32.5%] of patients, with transfusion of 3-9 units of blood [mean - 5.38]. Surgery was performed only in the retrospective group - in [11.11%]. Hospital stay time was for group [A] and [B] 17.5 and 9 days respectively. Overall death rate was [8.33%]; it was less in group [A] than [B] - [6.67%] and [13.3%] respectively. In patients treated only conservatively, death rates in [A] and [B] were [7.5%] and [13.3%] respectively. Nevertheless, death rates were statistically not significant. Overall outlook was quite alarming. Lack of good administration, limited resources, and lack of necessary equipments played the major role in improper management of these patients. To improve the situation, it is recommended to prepare guidelines and establish a well equipped and well functioning endoscopy unit


Subject(s)
Humans , Male , Female , Peptic Ulcer Hemorrhage/surgery , Retrospective Studies , Endoscopy, Gastrointestinal/statistics & numerical data , Recurrence , Peptic Ulcer Hemorrhage/mortality , Risk Assessment , Prospective Studies , Hospitals, Teaching
12.
13.
Rev. argent. cir ; 68(1/2): 1-13, ene.-feb. 1995. ilus
Article in Spanish | LILACS | ID: lil-172518

ABSTRACT

El uso de modernos bloqueantes de la secreción gástrica ha modificado poco la incidencia de complicaciones en la enfermedad ulcerosa gastroduodenal. En este trabajo, se analizan 1154 pacientes internados por hemorragia digestiva alta; el 93,7 por ciento eran portadores de úlcera gástrica, o duodenal, o recidivante. Se excluyó el sangrado por várices. Se utilizó la clasificación de Forrest modificada para determinar la posibilidad de sangrado considerándola útil. Noventa pacientes debieron ser operados sangrando, observándose una mortalidad del 34 por ciento y morbilidad del 66 por ciento. Este grupo de pacientes debe considerarse de alto riesgo. Los antecedentes clínicos pre-sangrado, shock en el momento del ingreso, y hemorragia complicando el post-operatorio, fueron factores significativos para el pronóstico. Debe realizarse un esfuerzo para evitar intervenciones en agudo. En este sentido, la hemostasia por vía endoscópica o la embolización endovascular, pueden reducir el número de operaciones de urgencia


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Gastrointestinal Hemorrhage/surgery , Postoperative Complications/etiology , Duodenal Ulcer/surgery , Stomach Ulcer/surgery , Peptic Ulcer Hemorrhage/surgery , Gastrointestinal Hemorrhage/etiology , Gastrointestinal Hemorrhage/mortality , Postoperative Complications/epidemiology , Severity of Illness Index , Duodenal Ulcer/complications , Stomach Ulcer/complications , Peptic Ulcer Hemorrhage/mortality
14.
Rev. Col. Bras. Cir ; 22(1): 23-7, jan.-fev. 1995. tab
Article in Portuguese | LILACS | ID: lil-154578

ABSTRACT

Säo estudados sessenta doentes portadores de UGPCH, que, após exame endoscópico, foram divididos em dois grupos. No grupo I (36 doentes), administrou-se cimetidine e/ou antiácido com intuito de coibir a hemorragia e praticar a operaçäo fora da fase aguda do sangramento. No grupo II (24 doentes), logo após exame endoscópico, os pacientes foram encaminhados para tratamento cirúrgico. Pôde-se observar que a necessidade de sangue, o índice de complicaçöes pós-operatórias, o tempo de hospitalizaçäo e a mortalidade foram maiores nos doentes do grupo I. Em virtude de nossos resultados, julgamos recomendável que doentes portadores de UGPCH sejam encaminhados para operaçäo em caráter imediato ao invés de serem submetidos a prévio tratamento conservador com administraçäo de climetidine e/ou antiácido


Subject(s)
Hemorrhage , Stomach Ulcer/surgery , Peptic Ulcer Hemorrhage/surgery , Stomach Ulcer/diagnosis , Stomach Ulcer/therapy , Peptic Ulcer Hemorrhage/diagnosis , Peptic Ulcer Hemorrhage/therapy
15.
Acta méd. (Porto Alegre) ; (1): 86-95, 1995. tab
Article in Portuguese | LILACS | ID: lil-198396

ABSTRACT

Os autores apresentam uma revisäo bibliográfica sobre o manejo clínico da úlcera duodenal hemorrágica, analisando os conceitos atuais sobre sua fisiopatologia, manifestaçöes clínicas e as novas alternativas terapêuticas utilizadas


Subject(s)
Humans , Peptic Ulcer Hemorrhage/therapy , Endoscopy , Peptic Ulcer Hemorrhage/surgery
16.
Rev. cient. AMECS ; 4: 45-9, 1995.
Article in Portuguese | LILACS | ID: lil-169539

ABSTRACT

Atualmente a grande maioria das úlceras pépticas sao tratadas com sucesso através de tratamento clínico. Entretanto, existem situaçoes em que o tratamento cirúrgico torna-se necessário e indicado. O presente trabalho tem como objetivo revisar as indicaçoes de tratamento cirúrgico para as úlceras pépticas, abrangendo suas principais manifestaçoes clínicas, investigaçoes diagnósticas e procedimentos cirúrgicos preferenciais.


Subject(s)
Humans , Male , Female , Peptic Ulcer/surgery , Elective Surgical Procedures , Pyloric Stenosis/surgery , Pyloric Stenosis/diagnosis , Duodenal Ulcer/surgery , Peptic Ulcer Hemorrhage/surgery , Peptic Ulcer Hemorrhage/diagnosis , Peptic Ulcer Perforation/surgery , Peptic Ulcer Perforation/diagnosis , Peptic Ulcer/complications
17.
Rev. méd. Hosp. Säo Vicente de Paulo ; 6(14): 13-5, jan.-jun. 1994. graf
Article in Portuguese | LILACS | ID: lil-191331

ABSTRACT

Quarenta e sete pacientes com sangramento do trato digestivo alto por úlcera péptica foram revisados. A relaçäo homem/mulher foi 3:2 com uma idade média de 38 a 55 anos, respectivamente. Vinte pacientes apresentavam úlceras gástricas, vinte e cinco duodenais e dois casos de úlceras combinadas. Houve recidiva da hemorragia em 26 pacientes, 15 com úlceras gástricas e 11 duodenais. Em 17 casos de úlceras com 2 cm. ou mais de diâmetro apenas uma näo sangrou. A mortalidade foi de 6,3 por cento. os achados endoscópicos sugerem evoluçäo do paciente e poderiam ser usados como critérios objetivos na decisäo de operar ou näo estes pacientes


Subject(s)
Humans , Stomach Ulcer/complications , Peptic Ulcer Hemorrhage/surgery , Peptic Ulcer Hemorrhage/diagnosis , Endoscopy, Digestive System
19.
Rev. colomb. gastroenterol ; 8(4): 211-5, oct.-dic. 1993. tab
Article in Spanish | LILACS | ID: lil-221436

ABSTRACT

Se evaluó el uso de oleato de etanolamina al 5 por ciento para escleroterapia endoscópica en úlcera péptica sangrante y en aquellos pacientes con signos predictores de resangrado. Ingresaron al estudio 60 pacientes y se distribuyeron en 2 grupos: los primeros 30 constituyeron el grupo control y los restantes 30 el grupo de esclerosis. A las 48 horas de observación 5 de 30 (16.6 por ciento) del grupo esclerosis y 15 de 30 (50 por ciento) del grupo control presentaron resangrado y fueron operados de urgencia (p menor 0.01). El requerimento promedio de transfusión en el grupo de esclerosis fue de 2.25 unidades de glóbulos rojos, y en el grupo control fue de 5.04 unidades(NS). Se observó disminución de la mortalidad en el grupo de esclerosis en comparación con el grupo control (p<0.01). De acuerdo al tamaño de la úlcera, disminuyó significativamente la necesidad de cirugía urgente en el grupo de esclerosis (p<0.05) para úlceras de menos de 2 centímetros, y (p<0.05) para úlceras mayores de 2 cms. En conclusión, la esclerosis endoscópica con oleato de etanolamina es una manera eficaz de producir hemostasia en pacientes con úlcera péptica sangrante y con signos predictores de alto riesgo para resangrado


Subject(s)
Humans , Oleic Acid/therapeutic use , Ethanolamine/therapeutic use , Sclerotherapy , Peptic Ulcer Hemorrhage/surgery
20.
Rev. chil. cir ; 45(4): 332-40, ago. 1993. ilus, tab
Article in Spanish | LILACS | ID: lil-130671

ABSTRACT

Se presenta la experiencia en el tratamiento endoscópico de la hemorragia digestiva alta, con Heat Probe. Durante dos años se presentaron 322 HDA, de los cuales 121 fueron tratados de acuerdo a los siguientes criterios: Sangrado activo arterial o difuso, vaso visible, coágulo centinela o protuberancia pigmentada. Se logró hemostasia en 35 de 41 pacientes con sangrado pulsátil (8 por ciento ), en 51 de 51 con sangrado difuso (100 por ciento ) y en 29 de los 29 pacientes con vaso visible, coágulo centinela o protuberancia pigmentada (100 por ciento ). Cuatro pacientes murieron; todos menores de 70 años y con una lesión ulcerosa profunda en cara posterior del duodeno. ASA III (N:1) y ASA IV (N:3), (p<0,01). Nuestros resultados sugieren que el tratamiento endoscópico con Heat Probe de una HDA es un método seguro y efectivo.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Electrocoagulation/methods , Endoscopy, Digestive System , Gastrointestinal Hemorrhage/surgery , Peptic Ulcer Hemorrhage/surgery
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