ABSTRACT
We describe a 62-year-old woman with Psoriasis who presented as Methotrexate-induced pericarditis and pericardial effusion. Aspiration of the pericardium was required and the patient made a satisfactory recovery. At six-months follow-up, she remained well, psoriasis plaques was controlled by topical crude coal tar and topical corticosteroid. These complications are extremely rare, but have been described as isolated phenomena associated with methotrexate therapy.
Subject(s)
Adrenal Cortex Hormones/therapeutic use , Dermatologic Agents/adverse effects , Echocardiography , Electrocardiography , Female , Follow-Up Studies , Humans , Methotrexate/adverse effects , Middle Aged , Pericardial Effusion/chemically induced , Pericarditis/chemically induced , Psoriasis/drug therapy , SuctionSubject(s)
Acute Disease , Aluminum Compounds , Humans , Pericarditis/chemically induced , Phosphines/poisoningSubject(s)
Acute Disease , Aluminum Compounds , Humans , Male , Middle Aged , Pericarditis/chemically induced , Pesticides/poisoning , Phosphines/poisoningABSTRACT
Se describe un pacientes de 11 años de edad con bocio multinodular hipertiroídeo que después de 26 meses de tratamiento con Propiltiouracilo sufrió una reacción adversa con la droga, con evidencias de pericarditis, vasculitis y granulocitopenia. Los síntomas desaparecieron rápidamente al suspender la droga. Posteriormente fue sometido a tiroidectomía y tratamiento hormonal de reemplazo