Acute poisoning with hair dye containing parapheny lenediamine: the Gezira experience

Objective:To review the experience of acute poisoning due to the ingestion of hair dyes containing paraphenylenediamine in the Gezira area. Clinical presentation, management, and outcome are discussed. A retrospective review of cases hospitalized during a 10-year period. A total of 122 cases were included. In 114 cases [93.4%], there was suicidal intent. In 4 cases [3.3%], ingestion was accidental. In 4 cases [3.3%], homicidal intent was suspected. There were 110 adult female patients [90%], 9 adult male patients [7.4%], and 3 children [2.6%]. Hair dyes containing paraphenylenediamine cause serious manifestations of hypersensitivity and systemic effects when ingested and may prove lethal. A program of education to raise public awareness of the dangers of this chemical and stricter rules regarding its use and circulation should be implemented to avoid criminal misuse

Metal chelates of o-phenylenediamine bis-isatin schiff base with La [III], Ce [III] Th [IV], Uo2 [VI], Ag [I] and Hg [II]

A series of La [III], Ce [III], Th [IV], UO2 [VI], Ag [I] and Hg [II] chelates with the Schiff base derived from isatin with o-phenylenediamine have been prepared and characterized by elemental analyses, 1H NMR, IR, UV-visible spectra and molar conductivity measurements. Analytical and other spectroscopic studies revealed that the Schiff base ligand reacts with the metal ions in 1:1 [metal: ligand] stoichiometry as dibasic tetradentate ligand through its ONNO ligating atoms. A non-electrolytic nature was suggested for these chelates except for that of Ag [I]