ABSTRACT
Intracranial hemorrhage is an uncommon complication of phenylpropanolamine. There is an increasing awareness of this complication in the West. However, to the best of our knowledge there have been no cases reported from India. Here we report a patient who developed Intraventricular hemorrhage following ingestion of Phenylpropanolamine, from which he made an uneventul recovery over the next two weeks.
Subject(s)
Adult , Cerebral Hemorrhage/chemically induced , Cerebral Ventricles , Humans , India , Magnetic Resonance Angiography , Male , Nasal Decongestants/adverse effects , Phenylpropanolamine/adverse effects , Tomography, X-Ray ComputedABSTRACT
When risks and benefits of phenylpropanolamine are analyzed, given the availability of safe alternatives in the cases in which it may be considered, it is concluded that its use is no longer justified because of the risks involved
Subject(s)
Humans , Phenylpropanolamine/adverse effects , Cerebral HemorrhageABSTRACT
We report 3 women aged 33, 63 and 43 years old receiving an anorexigenic medication that contained phenylpropanolamine who 30 min to 3 h after the ingestion of this medication, presented a frontal hematoma, a left putaminal hematoma and a subaracnoidal hemorrhage, respectively. Cerebral angiography, performed in all of them, did not show any vascular abnormality. This complication of phenylpropanolamine use has been reported previously abroad and the mechanism of production, could be related to an elevation of blood pressure and the production of a vasculitis by the drug. The risk of this complication must be taken into account when prescribing phenylpropanolamine