ABSTRACT
As the world celebrates the world polio day, the battle continues to end polio transmission in two of the last endemic countries in the world which happen to be both in the Eastern Mediterranean Region of WHO
Subject(s)
Humans , Poliovirus/drug effects , Poliomyelitis/drug therapy , Poliovirus Vaccine, Oral/therapeutic use , Disease EradicationABSTRACT
Se realizó un estudio en 32 entidades del país, cuyo objetivo fue la evaluación de la cadena de frío de la Secretaría de Salud de México, durante los "Días Nacionales de Vacunación Atipolimielítica" de 1987 y 1988. Se evaluó el cumplimiento de normas y la potencia de la vacuna en los diferentes niveles administrativos, para lo cual se llenaron formularios y se obtuvieron frascos de biológico cerrados en cada uno de estos niveles. Se encontró que sólo el 56 por ciento de las unidades muestreadas almacenaban exclusivamente biológico, más de 10 por ciento de los refrigeradores estaban en mal estado y el 44 por ciento de los responsables de la red frío consideraron insuficiente su capacidad de almacenamiento. Al comparar el cumplimiento de normas con la potencia de la vacuna se encontró correlación entre el grado de incumplimiento de normas y la caída de la potencia del biológico
An evaluation of the cold chain used during the "National Vaccination Days Against Poliomyelitis" in January and March of 1987 and 1988 was performed in 32 states of Mexico, both the potency of the trivalent Sabin vaccine and completion of requeriments for the maintenance of the cold chain were evaluated at each level in the Ministry of Health's structure. Only 56 percent of the refrigeration units exclusively stored vaccines, more than 10 percent of refrigerators were broken, and 44 percent of the persons responsibles for the cold chain system considered the storage capacity inadequate. A correlation was found between nonfulfilment of maintenance requeriments for cold chain and a decreased in vaccine potency.
Subject(s)
Poliovirus Vaccine, Oral/therapeutic use , Vaccination/methods , Poliomyelitis/prevention & control , Specimen Handling , Poliovirus Vaccine, Oral/standards , Mexico , Immunization Programs/prevention & controlABSTRACT
A survey of immunization status and serological immunity to polio was carried out in 5 parishes in Jamaica in 1985. A sample of 2,506 children and adolescents aged 1 - 19 years was chosen by selecting clusters of children in enumeration districts (EDs) in each parish from the 1980 Census. Immunization status was verified by examining immunization records. Serological assay for antibodies to Polio Types 1, 2 =, and 3 was done. A positive neutralization test at dilution of 1:8 was done. A positive neutralization test at dilution of 1:8 was taken as immunity to the polio virus. Of the 1,819 children whose immunization status was confirmed, coverage with 3 or more doses of roral polio vaccine was highest in the 1 - 4 year age group with with 79.7% and lowest in the 15 - 19-year age group with 37.4%. Of the 2,506 children 81.4%, 94.7% and 72.3% were seropositive for Polio Types 1, 2 and 3 respectively. There was a significant difference in the prevalence of seropositives between individuals with and those without a history of vaccinations. No urban/rural or sex differences were noted. The study indicated a higher level of immunization status than previous surveys and a high level of serological immunity to polio
Subject(s)
Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Humans , Poliovirus Vaccine, Oral/immunology , Antibody Formation , Poliovirus Vaccine, Oral/therapeutic use , Sampling Studies , JamaicaABSTRACT
Apresentação de um caso de poliomielite paralitica de cuja analítica fica demonstrado a sua relação com vacinação oral antipólio. Tal ocorrência seria resultado de completa ausência de triagem na vacinação, em, massa, muito embora tais casos ocorram mais sistematicamente em países onde já se conseguiu o controle da doença natural....