Prenatal sonographic evaluation and postnatal outcome of renal anomalies.

OBJECTIVE: To determine the prognosis of antenatally detected renal anomalies by sonographic evaluation. MATERIALS AND METHODS: This was a follow-up study of all antenatally detected renal anomalies from January 2008 to Dec 2009 referred to fetal medicine clinic. Prenatal evaluation was done and cases were divided into four groups depending upon their prenatal sonographic findings. Post natal follow-up was done up to one year in cases of live babies. Autopsy was carried out in still born fetus after consent. RESULTS: The renal anomaly was detected in 55 cases, which were fully followed. The prognosis was said to be poor for group I cases with gross extra renal anomaly along with the renal anomaly, and for group II in which there was organic renal pathology with loss of renal function suggested by non-visualization of bladder and almost absent liquor. Prognosis was guarded and depended upon the gestational age of presentation in group III, which had obstructive uropathy; prognosis was good in group IV cases, which were mild, unilateral or which presented late. CONCLUSION: Prenatal sonographic evaluation gives reasonably accurate picture of the prognosis and can be very helpful in counseling the parents regarding prognosis and help in deciding the timing and route of delivery.

real effect of toxoplasmosis on the outcome of pregnancy

A prospective study was carried out on 250 cases of pregnant women attending medical centre of Basrah University in their 1st trimester of pregnancy with an age range of 15-45 years from 1/7/1993-10/8/1996, to find out the real effect of toxoplasmosis on the outcome of pregnancy. The subject comprises of [150] cases of acute maternal toxoplasmosis during pregnancy, [115] of them had history of habitual abortion [history of 3 or more consecutive abortions] and 35 cases of sporadic abortion, the other [100] were taken as a control group [normal pregnant women]. All recently infected patients were treated with spiramycin or sulfadiazine according to the availability of drugs, in a dose of 250mg four times daily 14 days or 500mg twice daily for spiramycin or sulfadiazine respectively. The study shows that 54% of habitual abortion group their pregnancy ended by abortion, 10.5% of them go into preterm labor and 30.5% term pregnancy [6 of them lost follow up]. The study also show significant increase in the incidence of C/S [caesarean section] 15.2% in the habitual abortion group as compared to 6% among normal pregnant women, with also significant increase in the perinatal mortality rate among habitual abortion group as compared to normal pregnant women. 50% chance of congenital anomaly among perinatal death in habitual abortion group as compared to 25% among normal pregnant women

Parasitic infection and its effect on pregnancy out come indices among Egyptian women

800 pregnant women were included in this study. All cases were subjected to the following investigations: CBC, ABO system, RH factor, fasting and post prandial 2-hour blood glucose, BUN, serum creatinine, SGOT, SGPT, VDRL, urine, stool and ultrasound examination. Maternal weight, fetal birth weight ratio and placental ratio were calculated. 300 of them were examined for toxoplasmosis. Out of this group 75 women were considered as control. Indirect hemagglutination technique was used as screening test for detection of toxoplasmosis. It was found that there was a significant positive correlation between maternal weight and fetal birth weight ratio, while it was insignificant between maternal weight and placental ratio. So, it was important to diagnose this parasitic infestation routinely before and during pregnancy to avoid their complication, especially in the endemic areas, where warm climate, poor sanitation, bad habits and ignorance exist