Síntomas vasomotores en la mujer climatérica / Vasomotor symptoms in climateric woman

Introducción: los síntomas más precoces y característicos del período climatérico son los síntomas vasomotores, los cuales se producen por la pérdida intermitente del control vasomotor por la falta de retroalimentación negativa del estradiol sobre el hipotálamo. Objetivo: aportar un conocimiento actualizado sobre la fisiopatología de la sintomatología vasomotora presentada en la mujer climatérica. Métodos: se realizó una revisión bibliográfica actualizada sobre la sintomatología vasomotora relacionada con el síndrome climatérico. Se revisaron textos, revistas y monografías. Resultados: se confeccionaron cuadros resúmenes y esquemas de la fisiopatología de los síntomas, así como una propuesta de algoritmo para el manejo de los síntomas vasomotores en la Atención Primaria de Salud. Conclusiones: las modificaciones perimenopáusicas suelen comenzar durante la quinta década de la vida. En este período, los síntomas más precoces son los sofocos y sudoraciones que afectan al 75 - 85 por ciento de las mujeres

Introduction: the more precocious and characteristic symptoms of climateric period are the vasomotor symptoms, which are produced due to the intermittent loss of vasomotor control by lack of a negative feedback of estradiol on the hypothalamus. Objective: to provide an updated knowledge on the physiopathologic features of vasomotor symptomatology in climateric woman. Methods: authors carried out an updated bibliographic review on above mentioned symptomatology related to climateric syndrome, as well as texts, journals and monographs. Results: summarized pictures and schemes of the physiopathologic features of symptoms, as well as a proposal of algorithm for management of vasomotor symptoms in the Health Primary Care. Conclusions: the perimenopause modifications may to begin during the fifth decade of life. In this period the earlier symptoms include: suffocations and sweatings involving the 75-85 percent of women

Quality of life among perimenopausalSaudi working women and its impact on theirmenopausal symptoms

Menopause is emerged as a prominent issue in the women's health. It is a natural progression of women's life. Perception of menopausal symptoms is influenced by the broader social and cultural contexts in which such normative biological events are embedded. Some women viewed this period as an indicator of natural and inevitable life changes, while others view it as a problem that affects their quality of life. WHO defined quality of life as the individuals' perception of their status in life according to the cultural and value systems they live in, considering their aims, expectations, standards and worries. On the other hand, quality of life [QOL] is an important outcome that reflects the way women feel and function during menopausal period. So, this study aimed to identify the effect of quality of life among perimenopausal Saudi manager women on their menopausal symptoms. It was a descriptive study, where a convenient sample of 120 perimenopausal manager women, who are not using hormonal replacement therapy and willing to participate in the study, were selected from King Abdel Aziz University and King Abdel Aziz University Hospital in Jeddah. Two validated tools were used to collect data; menopausal symptoms inventory scale and Utain quality of life scale. The results clarified that the majority of perimenopausal women obtained moderate total score of QOL and a sizeable proportion got high total score of menopausal symptoms. The relationship between women's total score of QOL and their general characteristics was found to be statistically significant regarding level of education, years of work experience, marital status, and history of medical diseases. Statistically significant differences were also found between women's total score of menopausal symptoms and their general characteristics in relation to level of education, years of work experience, marital status, and age at marriage, duration of marriage, menstrual history, as well as history of medical diseases. Low and moderate total scores of symptoms were significantly higher among women with high total score of QOL, while high total score of symptoms was significantly higher among women with low and moderate total scores of QOL. quality of life had significant, negative effect on women's menopausal symptoms

Atención sostenida asociada con hormonas ováricas en mujeres en la premenopausia y posmenopausia / Sustained attention associated to ovarian hormones in premenopausal and posmenopausal women

El objetivo fue asociar la atención sostenida medida con la Prueba de Ejecución Continua con los niveles hormonales de LH, FSH, progesterona, estrona y estradiol en 10 mujeres en la posmenopausia y 10 en la premenopausia. Este último grupo fue evaluado en la fase menstrual, con bajos niveles hormonales y en la fase ovulatoria, con altos niveles hormonales. Se analizó el número de aciertos, errores, omisiones y tiempo de reacción en dos niveles de dificultad de la prueba. El número de aciertos en el segundo nivel de dificultad de la prueba de las mujeres premenopáusicas, en fase ovulatoria, fue mayor (p=0.019) y cometieron menos errores (p=0.019) comparadas con las mujeres en la posmenopausia. En la posmenopausia, el número de aciertos se asoció positivamente con la progesterona (p<0.0001), FSH (p<0.001) y estrona (p<0.0001) y negativamente con LH (p<0.03). En la premenopausia, en fase menstrual, los aciertos se asociaron negativamente con progesterona (p<0.0001), LH (p<0.0001) y estrona (p<0.0001). En la fase ovulatoria, los aciertos se asociaron positivamente con FSH (p<0.0001), progesterona (p<0.0001) y estrona (p<0.0001) y negativamente con LH (p<0.0001). Estos resultados sugieren que las hormonas sexuales pueden influir en la atención sostenida en mujeres en la transición hacia la menopausia.

The aim was to associate the sustained attention, measured by means of the Continuous Performance Test with hormonal levels of FSH, LH, progesterone, estradiol and estrone, in ten posmenopausal women and ten premenopausal women. This last group was evaluated in menstrual phase, with low hormonal levels, and during the ovulatory phase, with high hormonal levels. The number of correct responses, errors, omissions and reaction time during two levels of difficult of the test were obtained. The number of correct responses made by the premenopausal women in the ovulatory phase was high (p=0.019),and they committed less errors (p=0.019) during the second level of difficult of test compared with posmenopausal women. In the posmenopause, the number of correct responses was positively associated with progesterone (p<0.0001), FSH(p<0.001), and estrone (p<0.0001), and negatively associated with LH (p<0.03). In the premenopause, in menstrual phase, the correct responses were negatively associated with progesterone (p<0.0001), LH (p<0.0001) and estrone (p<0.0001). In the ovulatory phase, the correct responses were positively correlated with FSH (p<0.0001), progesterone (p<0.0001) and estrone (p<0.0001), and negatively with LH (p<0.0001). These findings suggest that the sex hormones may influence on sustained attention in women in transition to menopause.

Depressão e ansiedade em mulheres climatéricas: fatores associados / Depression and anxiety in menopausal women: associated factors

OBJETIVO: determinar a prevalência de depressão e ansiedade em mulheres climatéricas e os prováveis fatores responsáveis por sua ocorrência. MÉTODOS: em estudo transversal, foram selecionadas 93 mulheres que frequentaram um ambulatório de climatério no período de maio de 2006 a agosto de 2007. Como critério de inclusão foram consideradas mulheres na faixa etária de 40 a 65 anos e que concordaram em participar do projeto. Os critérios de exclusão foram: pacientes em uso de terapia hormonal, hormonioterapia por implantes, DIUs e injetáveis de depósito nos últimos seis meses, endocrinopatias que levassem a irregularidades menstruais, hepatopatias, coagulopatias, uso de drogas que interferissem no ciclo menstrual, ansiolíticos e antidepressivos (pois o uso dessas drogas era indicativo de diagnóstico prévio de alterações do humor), histerectomizadas, ooforectomizadas, portadoras de câncer e de enfermidades psiquiátricas, pacientes que tivessem sido submetidas à radioterapia ou quimioterapia. Foram aplicados quatro questionários durante a entrevista: Anamnese, contendo dados sociodemográficos, clínicos e hábitos de vida; Índice Menopausal de Blatt-Kupperman, com o objetivo de diagnosticar as pacientes portadoras de síndrome climatérica; a subescala para Ansiedade, derivada da escala Hospitalar para Ansiedade e Depressão (HADS-A), com a finalidade de diagnosticar os casos de Ansiedade e o Inventário de Depressão de Beck, com o intuito de diagnosticar as mulheres portadoras de depressão. Foram realizadas as análises descritivas e de correlação entre as variáveis; o teste do χ2 e de Hosmer-Lemeshow, usando o programa Software Statistica versão 6. RESULTADOS: a média de prevalência de depressão entre as pacientes avaliadas foi de 36,8 por cento enquanto que da ansiedade foi de 53,7 por cento. Não houve diferença significativa entre a prevalência de depressão e ansiedade e as três fases do climatério. Observou-se relação significativa entre...

PURPOSE: to determine the prevalence of depression and anxiety in climacteric women and the probable factors responsible for its occurrence. METHODS: a transversal study that has selected 93 women attended at a climacteric outpatient clinic, from May 2006 to August 2007. Inclusion criteria were: women from 40 to 65 years old who agreed with participating in the project. Exclusion criteria: patients in hormonal therapy, hormone-therapy by implant, DIUs and depo injections in the preceding six months, endocrinopathies leading to menstrual irregularities, hepatopathies, thrombopathies, use of drugs which interfere in the menstrual cycle, anxiolytics and antidepressants (as their use indicates previous diagnosis of mood disorders), hysterectomy, oophorectomy, cancer or psychiatric disease, and patients who had been submitted to radio or chemotherapy. During the interview, four questionnaires were applied: Anamnesis, containing socio-demographic, clinical and living habits data; Blatt-Kupperman's Menopausal Index for climacteric syndrome diagnosis; Anxiety sub-scale of the Hospital Anxiety and Depression scale (HADS-A) for anxiety diagnosis; and Beck's Depression Inventory for the diagnosis of depression. Descriptive and correlation analysis among the variables, χ2 and Hosmer-Lemeshow tests were performed using the Statistica Software program, version 6. RESULTS: the average depression prevalence among the patients was 36.8 percent, while that of anxiety was 53.7 percent. There was no significant difference between the prevalence of depression and anxiety in the three phases of climacterium. There was a significant relationship between the presence of moderate climacteric symptoms and the presence of mood alterations (p<0.001). Depression was more frequent in women with anxiety (OR=4.2) and insomnia (OR=4.9), having a job being a protection factor (OR=0.2). Risk factors related to anxiety were the presence of depression (OR=6.1) and antecedents...

Prevalência de sintomas depressivos na perimenopausa / Depressive symptoms prevalence in the perimenopause

OBJETIVO: realizar revisão sistemática de estudos de prevalência dos sintomas depressivos na perimenopausa. MÉTODO: A pesquisa foi efetuada a partir das bases de dados MEDLINE e EMBASE. Foram incluídos estudos transversais originais com populações adultas (idade de 40 a 55 anos), no período de 1996 a 2006, que estimaram a prevalência de sintomas depressivos na perimenopausa nos idiomas: inglês, francês, espanhol e português. A seleção dos estudos pela estratégia de busca foi feita de forma independente por dois avaliadores. Foram incluídos os estudos que preencheram os seguintes critérios metodológicos: características epidemiológicas, definições de perimenopausa, instrumentos válidos utilizados para sintomas depressivos. RESULTADOS: Após a avaliação de 1.345 artigos, restaram apenas cinco que caracterizaram uma população de 11.020 mulheres com idades entre 40 e 60 anos. Constatamos que a prevalência de sintomas depressivos na perimenopausa variou entre 19 por cento e 73 por cento. CONCLUSÃO: A presente revisão sistemática mostrou expressiva variação na prevalência de sintomas depressivos na perimenopausa; ademais, não foi possível caracterizar se a sintomatologia depressiva na perimenopausa decorreu exclusivamente de flutuações hormonais observadas neste estágio da vida ou de antecedentes prévios de depressão.

OBJECTIVE: a systematic review of studies that investigated the prevalence of depressive symptoms in perimenopausal women. Method: The research was conducted in MEDLINE and EMBASE databases. Original transversal studies in from 1996 to 2006 with adult populations were enclosed (age between 40 and 55 years old) and demonstrated prevalence of depressive symptoms in the perimenopause in the following languages: English, French and Portuguese. The studies selection was conducted by two independent evaluators. The inclusion criteria were studies which fulfilled the following methodological criteria: epidemiological characteristics, perimenopause definitions and valid instruments to evaluate depressive symptoms. RESULTS: After the evaluation of 1.345 articles, 1099 were excluded since they did not satisfy the criteria of inclusion, remaining only five articles with a population of 11.020 women with ages between 40 and 60 years and, therefore, part of the studied sample enclosed in perimenopause. This study revealed a prevalence of depressive symptoms in perimenopause, which varied between 19 percent and 73 percent. CONCLUSION: The present systematic review showed substantial variation in the prevalence of depressive symptoms in perimenopause; in addition, it was not possible to characterize if the depressive symptoms in perimenopause were exclusively due to hormonal fluctuations in this stage life or if related to previous preceding moments of depression.

Alterações cognitivas em mulheres com quadros depressivos na perimenopausa: o efeito da terapia de reposição hormonal com estradiol transdérmico / Cognitive alterations in women with depressive disordes during perimenopause: the impact of hormone therapy with trasdermal estradiol

A perimenopausa é a fase da vida reprodutiva feminina caracterizada diversas alterações, inclusive cognitivas devido ao hipoestrogenismo. Através de estudo duplo-cego randomizado com 16 mulheres na perimenopausa deprimidas que receberam estradiol e 16 que receberam placebo analisou-se as alterações cognitivas da atenção, memória e linguagem; o efeito da reposição hormonal com estradiol e a correlação entre os sintomas depressivos e menopausais com as alterações destas funções. Os resultados mostraram: melhora do controle inibitório, memória imediata e tardia (verbal e visual) e da capacidade de nomeação nos dois grupos; melhora dos sintomas depressivos e menopausais para o grupo que recebeu reposição hormonal: e não correlação entre a melhora destes sintomas e a melhora das funções cognitivas. Perimenopause is the female reproductive life period characterized by several changes including cognitive impairments related to hypoestrogenism. In a randomized double-blind study 16 depressive perimenopaused women took estradiol, while another group of 16 depressive perimenopaused women took placebo. Cognitive alterations associated to attention, memory and language, and estradiol hormone replacement therapy effects were evaluated. In addition, correlations among symptoms of depression and menopause, and cognitive alterations were also analyzed. The results had shown, in both groups, an improvement in inhibitory mental control, in immediate and delayed (verbal and visual) memory, and in naming capacity. In the group that received hormone replacement therapy our findings revealed a weakening of depression and menopause symptoms, which had shown no correlation with cognitive functions.

Influencing Factors on Quality of Life in Pre- and Postmenopausal Women / 간호학회지

PURPOSE: This study was to investigate the factors influencing quality of life and difference of quality of life in a postmenopausal group compared to premenopausal women. METHOD: The subjects consisted of 213 women from 40 to 64 years old. The data were collected from June 1, 2003 to June 31, 2004 using structured questionnaires which included questions relating to demographic and obstetric background and 4 scales(climacteric symptoms scale, marital satisfaction scale, sex-role attitude scale, quality of life scale). RESULT: Comparing pre- and postmenopausal women, significant statistical differences were demonstrated in climacteric symptoms and sex-role attitude. However, quality of life was not different between pre- and postmenopausal women. In premenopausal women, marital satisfaction(32.7%) and educational level(8.0%) were significant predictors to explain quality of life. Marital satisfaction(12.9%) was significant predictor to explain quality of life in postmenopausal women. CONCLUSION: No difference of quality in life between pre- and postmenopausal women provides information for changing traditional approaches of menopause according to physiological changes as illness. In addition the study showed that it is necessary to use marital satisfaction information when developing nursing interventions to promote the quality of life.

Alterações cognitivas em mulheres com quadros depressivos na perimenopausa: o efeito da terapia de reposição hormonal com estradiol transdérmico / Cognitive alterations in perimenopaused women with clinical depression: estradiol transdermic hormone replacement therapy effects

A perimenopausa é a fase da vida reprodutiva feminina caracterizada diversas alterações, inclusive cognitivas devido ao hipoestrogenismo. Através de estudo duplo-cego randomizado com 16 mulheres na perimenopausa deprimidas que receberam estradiol e 16 que receberam placebo analisou-se as alterações cognitivas da atenção, memória e linguagem; o efeito da reposição hormonal com estradiol e a correlação entre os sintomas depressivos e menopausais com as alterações destas funções. Os resultados mostraram: melhora do controle inibitório, memória imediata e tardia (verbal e visual) e da capacidade de nomeação nos dois grupos; melhora dos sintomas depressivos e menopausais para o grupo que recebeu reposição hormonal: e não correlação entre a melhora destes sintomas e a melhora das funções cognitivas.

Perimenopause is the female reproductive life period characterized by several changes including cognitive impairments related to hypoestrogenism. In a randomized double-blind study 16 depressive perimenopaused women took estradiol, while another group of 16 depressive perimenopaused women took placebo. Cognitive alterations associated to attention, memory and language, and estradiol hormone replacement therapy effects were evaluated. In addition, correlations among symptoms of depression and menopause, and cognitive alterations were also analyzed. The results had shown, in both groups, an improvement in inhibitory mental control, in immediate and delayed (verbal and visual) memory, and in naming capacity. In the group that received hormone replacement therapy our findings revealed a weakening of depression and menopause symptoms, which had shown no correlation with cognitive functions.

Validación de un cuestionario para la medición de las creencias sobre el climaterio / Validation of a questionnaire for measurement of beliefs about the climacteric

OBJECTIVE: To design an instrument for measuring beliefs about the social, psychological, and physiological consequences of women's climacteric stage. MATERIAL AND METHODS: The study included 340 women affiliated to Instituto de Seguridad y Servicios Sociales para los Trabajadores del Estado (Institute for Social Services and Security for State Workers, ISSSTE) (age mean = 49.46, (SD 7.92). The mean number of pregnancies in the sample was 3.75 (SD 2.57), and the mean number of born children was 3.21 (SD 2.19); 48 of women were premenopausal, 10.9 perimenopausal, and 40.6 postmenopausal. The instrument consisted of 25 items. RESULTS: A factorial analysis with Varimax rotation was carried out. Four factors were confirmed: disadvantages (alpha = 0.769), advantages (alpha = 0.839), physiological (alpha = 0.659), and psychological (alpha = 0.711). CONCLUSION: This instrument shows good internal consistency, and measures four climacteric belief groups: a) beliefs on disadvantages, b) beliefs on advantages, c) beliefs on physiological ailments, and d) beliefs on psychological symptoms. All three confirmed dimensions of the climacteric phase have been proposed in other studies.

Transtornos da sexualidade e perfil psicopatologico da mulher perimenopausa / Alterations of sexuality and psycological profile of women during perimenopause

O objetivo deste estudo foi avaliar a presenca de fatores psicologicos em amostra de mulheres perimenopausa com queixa de insatisfacao sexual. O processo dessa investigacao se deu por meio de aplicacao da escala de sexualidade GRISS feminina, da escala de...

The perimenopause, depressive disorders, and hormonal variability

CONTEXT: Several investigations have postulated that the perimenopause may represent a period of increased psychiatric vulnerability, particularly for mood disorders. This review characterizes the perimenopause, including biological changes, the influence of psychosocial factors and the most common clinical manifestations. Clinic-based studies and community-based surveys addressing the prevalence of depressive symptoms in perimenopausal women are critically reviewed. We also discuss the potential greater vulnerability to mood disturbance during the perimenopause in response to hormonal variability. A therapeutic algorithm for management of depressive symptoms in middle-aged perimenopausal women is also presented. The role of estrogen in the treatment of perimenopausal depressive symptoms is particularly discussed. In addition, we review the existing data regarding the potential efficacy of estrogen as an antidepressant agent (monotherapy, augmentation strategy or prophylaxis). DESIGN: Narrative review

Prevalencia de síntomas biológicos y psicológicos en mujeres perimenopáusicas, según estrato socioeconómico, en la ciudad de Temuco / Prevalence of biological and psychological symptoms in perimenopausal women of different socioeconomic levels Temuco city

Background: Psychological and biological symptoms occur in the perimenopausal period. However the real prevalence of these, is not well known in Chile. Aim: To determine the prevalence of biological and psychological symptoms and self care sexual health practices of perimenopausal women of Temuco, Chile. Patients and methods: A random sample of 171 women aged 45 to 55 years old, affiliated to private preventive health institutions and community organizations, were studied. These women were stratified in three income levels. Chi square, Fisher test and ANOVA were used for statistical analysis. Results: Bone and muscle aches were the most frequent referred symptoms in 36 percent of women. Thirty one percent complained of vaginal dryness and 28 percent of headache. No differences in symptom frequency per age or between post or pre menopausal women, were observed. Depressive disorders were found in 39 percent of women, mostly in women not working outside their houses. In the previous two years, 67 percent of women had a PAP smear and 58 percent had a mammography performed. Women of low income levels had a greater prevalence of biological and psychological symptoms and a lower frequency of self care behaviors. Conclusions: The most frequent symptom among the studied women was bone and muscle aches, followed by vaginal dryness. These results differ from other publications that report flushing as the most important symptom among perimenopausal women

Prevalencia de síntomas psiquicos y vasomotores en diferentes periodos del climaterio / Prevalence of vasomotor and psychic symptoms in different periods of the climateric

Las mujeres climatéricas presentan una amplia gama de síntomas vasomotores y psíquicos, sin embargo los estudios psiquiátricos muestran resultados contradictorios sobre los efectos de la menopausia en la sintomatología psíquica. Para conocerlos, estudiamos la prevalencia de síntomas, evaluados según BlattKupperman, en 1167 mujeres de 40 a 59 años de edad en su examen de Medicina Preventiva. Cuarenta y dos por ciento de estas mujeres habían presentado ya su menopausia, siendo la mediana de edad de presentación de ella, 48,3 años. En relación con los síntomas climatéricos, se observa que su prevalencia no cambia significativamente al acercarse la edad de la menopausia; sólo los bochornos y los dolores osteoarticulares aumentan después de los 50 años. La mayoría de los síntomas psíquicos no aumentan con la edad e incluso algunos, como la irritabilidad y el llanto fácil disminuyen en las mujeres mayores. En cambio, al analizar la prevalencia de los síntomas según la etapa del climaterio en que se, encontraban las mujeres, se observa que la mayoría de los síntomas se incrementan en el período perimenopáusico y posteriormente decrecen. Conclusión: la mujer en la postmenopausia tiene menos síntomas psíquicos y vasomotores que en la perimenopausia, período este último, de gran sintomatología y deterioro de la calidad de vida

Prevalencia y abandono de la terapia hormonal de reemplazo / Prevalence and dropout of the replacement hormonal therapy

Los beneficios de la terapia hormonal de reemplazo (THR) som apliamente conocidos, sin embargo un alto porcentaje de mujeres no se trata o abandona precozmente el tratamiento. Con el objeto de conocer el porcentaje de mujeres que siguen tratamiento, la respuesta terapéutica que obtienen, el tiempo que siguen la terapia y las causas de su abandono, se encuestaron 505 mujeres de 40 a 59 años de edad. El 43 porciento de las postmenopáusicas estaba con THR, no variando la prevalencia de tratamiento con la edad, pero si con el nivel de educación. Las mujeres con terapia reconocen una mejoría significativa de los bochornos, la depresión, la líbido y la capacidad laboral. A pesar de los beneficios, de 201 mujeres que habían iniciado el tratamiento, 70 (34,8 porciento) la abandonaron, después de una mediana de duración de 6 meses, mientras que las que continuaban, tenían una mediana de 20 meses. Aplicando tablas de vida se observa que a los 3 meses continuaba con la THR 85.6 porciento de las mujeres que comenzaron su tratamiento; a los 12, 69.6 porciento y a los 48 meses, 59.6 porciento. La primera causa de abandono de la terapia fue indicación de médicos (41.4 porciento de los casos de abandono). Sólo 1 paciente dejó el tratamiento por reaparición de sus menstruaciones. Se observa que un alto porcentaje de mujeres está con THR y que aunque el abandono es frecuente en los primeros meses de iniciada la terapia, más de la mitad de las mujeres continúan aún en tratamiento después de 4 años de iniciada. Se requieren esfuerzos educativos para mejorar estas cifras

Síntomas somáticos durante el climaterio, asociados con estados depresivos / Somatic symptoms during menopause associated to depressive states

Antecedentes: El periodo del climaterio ha sido un tema de interés desde el siglo pasado, por ser una etapa que se caracteriza por una gran variedad de síntomas en los diferentes sistemas. Las explicaciones que se han dado hasta el momento abarcan desde lo fisiológico hasta lo afectivo. En la actualidad se conoce que el 75 por ciento de las mujeres presentan una diversidad de trastornos los cuales estan asociados a factores de tipo afectivo, presetándose por las circunstancias propias de la historia y situación de vida, involucrando también la visión de la sexualidad, todo lo anterior identifica a la menopausia con un detonador de los síntomas emocionales, como en la depresión en mujeres climatéicas. Objetivo: Realizar mediciones en todas aquellas características emocionales que la literatura ha consignado, para poder obtener un perfil de nuestra población de pacientes en la etapa climatérica. Material y método: Por tal motivo se realizó una investigación exploratoria, transversal, con 149 pacientes de la clínica de climeterio del INPer. Las variables: independienteclimaterio; dependientes-depresión-sintomatología; controladas-edad-escolaridad-estado-civil-socio-económico. Los instrumentos empleados fueron: EAMD, encuesta de síntomas, los resultados refieren a una población con un promedio de edad de 49 años, perteneciente a la etapa postmenopáusica el 53.7 por ciento, 98 por ciento pertenecen a una clase media y baja, con una educación promedio de 9.06, y respecto a su ocupación, el 66.4 por ciento se dedicaba al hogar y su estado civil fue preponderantemente de mujeres casadas 57.7 por ciento, el promedio de embarazos fue de 4.63 y de hijos vivos de 3.4. Resultados: De la encuesta de síntomas, se encontró que de los 10 síntomas más frecuentes contestados 6 muestran aspectos de tipo psicológico. Con un promedio 16.29 síntomas referido por paciente. El 70.79 por ciento presentan síntomas de tipo depresivo. Conclusión: Las quejas somáticas múltiples referidas como severas, están asociadas de manera importante con estados emocionales de fondo depresivo. La atención integral de la paciente en el climaterio de contemplar la incorporación en el equipo interdisciplinario, de personal del área de la salud mental