ABSTRACT
El complejo Pseudallescheria/Scedosporium y taxas relacionados, pertenecientes a un grupo de microhongos con conidios viscosos e integrantes del orden Microascales, se presentan en diversos ambientes comunes asociados a las actividades humanas, ya sea en el suelo como en aguas contaminadas. Actualmente se consideran entre los mayores grupos de hongos filamentosos oportunistas causante de infecciones cutáneas y profundas en el hombre y otros mamíferos. El objetivo principal de este trabajo, consiste en reunir los datos primarios morfofisiológicos más relevantes, útiles para el micólogo médico en el laboratorio, con el aporte adicional de algunos aspectos, biológicos, ecológicos, taxonómicos y moleculares complementarios descritos en la literatura moderna.
The Pseudallescheria/Scedosporium complex and their related taxa are a group of fungus that conidia are presents in viscous mass and belong to the order Microascales. They are in several common enviroment related to human activities either in soil as in contaminated water. Nowadays they are considerated one of the most opportunistic group of filamentous fungus that may cause superficial and deep skin mycoses infections in man and other mammalian. The aim of this work is to gather the primary relevant morphophysiological aspects, usefull to the medical mycologist in the laboratory, plus the contribution of some of biological, ecological, taxonomical and moleculars complementary aspects that are describe in modern literature.
Subject(s)
Dermatomycoses , Mycoses , Pseudallescheria/isolation & purification , Pseudallescheria/cytology , Pseudallescheria/classification , Pseudallescheria/physiology , Scedosporium/isolation & purification , Scedosporium/cytology , Scedosporium/classification , Scedosporium/physiologyABSTRACT
We report a case of recurrent sino-nasal fungal infection due to Pseudallescheria boydii (P. boydii) in a 33-year-old diabetic woman. It is very essential to identify P. boydii, as Miconazole is the only antifungal drug of choice. However, histological examination of the specimen for clinching clues such as intercalary conidia and chlamydoconidia plays an important role in identifying P. boydii, when fungal culture fails to yield the growth. On follow-up, the woman responded for the treatment with Miconazole and is free of symptoms, with no recurrence after 6 months.
Subject(s)
Adult , Antifungal Agents/therapeutic use , Diabetes Complications , Female , Frontal Sinusitis/drug therapy , Humans , Miconazole/therapeutic use , Mycoses/diagnosis , Pseudallescheria/isolation & purificationSubject(s)
Adrenal Cortex Hormones/adverse effects , Adult , Antifungal Agents/therapeutic use , Brain Diseases/diagnosis , Central Nervous System Fungal Infections/diagnosis , Fatal Outcome , Humans , Immunocompromised Host , Leprosy, Lepromatous/drug therapy , Lung Diseases, Fungal/diagnosis , Male , Pseudallescheria/isolation & purificationABSTRACT
Paciente de sexo femenino, 48 años, sin antecedentes clínicos de importancia presenta obstrucción nasal, rinorrea y poliposis. La tomografía axial computadorizada revela masa heterogénea en cavidad maxilar y paranasal derechas, fosa nasal con desviación del tabique y erosión ósea. Se efectúa sinusotomía maxilar derecha y del material se aísla pseudallescheria boydii. Recibe tratamiento con anfotericina B 975 mg hasta tipificación del agente etiológico; continúa con itraconazol 200 mg/día hasta la fecha (9 meses) sin recidivas
Subject(s)
Humans , Female , Middle Aged , Pseudallescheria/isolation & purification , Sinusitis/etiology , Itraconazole/administration & dosage , Itraconazole/therapeutic use , Pseudallescheria/drug effects , Pseudallescheria/pathogenicityABSTRACT
Os autores fazem relato de um caso de eumicetoma produzido por Petriellidium boydii. Ao exame direto, observaram-se gräos branco-amarelados, que cultivados em agar Sabouraud, mostraram, à micologia, conídios característicos. Após um mês de cultivo, observaram-se elementos esféricos cujo exame microscópico mostrou cleistotécios abertos e fechados. A paciente foi submetida a diferentes esquemas de tratamento, näo demostrando melhora no quadro. Há um mês, foi alterado o tratamento para ketocconazole, näo havendo ainda, tempo suficiente para observaçäo do seu efeito