ABSTRACT
To perform an incidence and typing study of P. aeruginosa catheter associated urinary tract infection [CAUTI] in two departments of Assuit University Hospital; the department of Urology and the Intensive Care Unit [ICU]. This study was done along the period of about 4 months. It involved 150 hospitalized patients in Assiut University Hospital; half of them from the department of Urology, and the other half were from the intensive care unit [ICU]. They were divided into two groups; cases and control. The case group included 100 patients having urinary catheters for more than 3 days, with age between 10 and 63 years old. Of the case group 65 were male patients and 35 were female patients. The control group included 50 age and sex matched hospitalized non-catheterized patients; half of them were from the department of Urology, and the other half from the ICU. Urine sample were collected from both the case and control groups and examined for bacteriuria and pyuria. Then examined bacteriologically [cultural characteristics and biochemical reactions] for isolation of P. aeruginosa. The isolates were typed by pyocine typing. Catheter-associated urinary tract infection [CAUTI] represents a great proportion of nosocomial UTI. The incidence in the department of urology was significantly higher than that in the ICU. Old age, female sex, diabetes, catheterization for more than 6 days, all favors the occurrence of CAUTI. The pre-use of second, third generation cephalosporins or quinolones decreased the incidence of CAUTI while the pre-use of ampicillin and gentamicin elevated that incidence. Most of the diagnosed CAUTI cases were caused by gram negative bacilli, which were mostly single infection. Incidence of P. aeruginosa UTI was significantly higher in cases than in controls. That incidence was equal in the two studied departments. There is a high incidence of CAUTI in Assiut University Hospital. And a high level of P. aeruginosa infection. So we recommend the use of the different preventive measures