ABSTRACT
Cardiac hydatid cyst [CHC] is a rare disease that was endemic in some regions especially in sheep-raising areas. The most commonly accepted theory for the routes of heart involvement in hydatid cyst was infestation by the hexacanthus embryo through coronary arteries.Here, we describe a case with the primitive cardiac hydatid cyst located around the pulmonary valve [PV] and main pulmonary artery [mPA] extended to right and left pulmonary arteries and metastasized to both lungs. Could it be possible for the embryo to adhere PV and mPA directly
Subject(s)
Humans , Male , Echinococcosis/complications , Echinococcosis/therapy , Pulmonary Artery/parasitology , Pulmonary Valve , Enzyme-Linked Immunosorbent AssayABSTRACT
Juvenile worms of Angiostrongylus cantonensis recovered from subarachnoid spaces and pulmonary arteries of rats, respectively, at 28 days post-infection have been compared with respect to their surface composition, antigenicity of surface proteins and morphological appearance. Quantitative and qualitative differences were shown between surface proteins of these two stages of worms. One major and 6 minor proteins appeared on brain stage worm's surface as assessed by surface-labelling and SDS-PAGE techniques. The same, but more predominant banding pattern, with one additional major protein of Mr 80,000 kDa presented on the lung stage worm's surface. Surface components from both stages were antigenic in permissive rat hosts but refractory in nonpermissive human hosts. The surface antigens are common to both stages within the rat. Observed by scanning electron microscopy, the surface appearance of brain stage worms is thickened, rough and irregular. Besides, particle clusters adhere randomly, without cluster adherence but transverse and longitudinal clefts were shown on the surface, before the outer layer was shed. The possible mechanisms of evasion from the host's immune attack with the surface-shedding phenomenon remain to be elucidated.
Subject(s)
Angiostrongylus/growth & development , Animals , Antigens, Helminth/immunology , Membrane Proteins/immunology , Meningoencephalitis/parasitology , Microscopy, Electron, Scanning , Pulmonary Artery/parasitology , Rats , Rats, Inbred Strains , Subarachnoid Space/parasitologyABSTRACT
Foi identificado Angiostrongylus vasorum (Baillet, 1866) colhido da artéria pulmonar de dois cäes (Canis familiaris) procedentes do município de Caratinga, Estado de Minas Gerais, Brasil. É apresentada a descriçäo morfológicas do parasita. Esta é a primeira referência desse parasita no Estado de Minas Gerais