ABSTRACT
Radiofrequency ablation has become a common trend in management of cases of AF refractory to medical treatment. Recurrence of AF is a common observation both acutely and late during follow up. To determine the clinical predictors of acute reconnection of pulmonary vein potentials during PVI and late recurrence of AF on follow-up, respectively. A cohort of 14 patients referred to the EP labs of the NHI and Ain Shams University for PVI between January 2007 and February 2008 were studied. PVI of arrhythmogenic PVs was performed segmentally. PVI was defined as entry and exit block using a multipolar Lasso catheter. All veins were resampled to confirm isolation after 20-60niinutes. There were 14 patients who underwent isolation of 56 pulmonary veins during the study period. Acute reconnection of at least one vein occurred in 7 patients [50%] and 10 of the 56 pulmonary veins targeted [18%]. The left superior PV was most likely to acutely recover conduction compared with the other veins. Predictors of acute reconnection could not be accounted for given possible technical difficulties and the small sample size. During the three month follow up period, recurrence of AF occurred in 3 patients representing 21.4% of the cohort. It was found to be higher in female gender, left atrial size>or equal 4.Scms, age older than 50 years, non-paroxysmal type of AF and an EF of less than 50%. Many clinical criteria can affect acute reconnection of PVPs during PVI for patients with AF. According to previous studies large left atrium, older age, hypertension, non-paroxysmal type of AF are the most likely acute predictors. As regards short term follow-up, factors that could be considered include gender, age, left atrial size, EF and type of AF. The importance of detection of acute recurrence of PVPs and re-isolation has also become evident through this study